Derm 1 - Westra Acne

Front 1

Pathophysiology of Acne:
Excessive _____ production
_______ plugging
Colonization of sebaceous follicle with _________ acnes
Immune response with ________

Back 1

sebum
follicular
Propionibacterium
Inflammation

Front 2

Open comedo =
Closed comedo =

Back 2

blackhead
whitehead

Front 3

Stress increases the output of ______ steroids - affecting the sebaceous gland

Back 3

adrenal

Front 4

Anabolic steroids, corticosteroids, Isonizid, Lithium, and Phenytoin are all known to do what?
Also Imuran, cyclosporine, disulferam, phenobarbital, quinidine, Vitamin B12

Back 4

Trigger acne
steroids, seizure/anti-psychotic drugs

Front 5

Classification:
Presence of few to several papules and pustules, no nodules

Back 5

Mild Acne

Front 6

Classification:
Several to many papules and pustules, along with a few to several nodules

Back 6

Moderate acne

Front 7

Classification:
Numerous or extensive papules and pustules, plus many nodules

Back 7

Severe acne

Front 8

Comedonal acne - open and closed comedones with few inflammatory lesions. Treat with topical ______ agents
Inflammatory acne: comedonal lesions plus inflammatory lesions - erythmeatous papules and pustules. Treat with ____ agents and systemic ______
Nodulocystic acne: Extensive comedonal lesions, inflammatory papules/pustules, nodules/cysts or abscesses
tx?

Back 8

keratolytic
topical
antibiotics
Topical not effective, 8 wks oral antibiotics. if that doesn't work, minocycline or isotretinoin

Front 9

Superficial non-inflammatory, open and closed comedones, flesh colored papules, no inflammation/pustules/nodules/scars

Back 9

Grade I acne

Front 10

Superficial inflammatory, open and closed comedones, inflammation, papules/pustules - few to several, no nodules/scars

Back 10

Grade II acne

Front 11

Deep inflammatory, moderate to severe, open and closed comedones, papules/pustules, few nodules, little to no scar present

Back 11

Grade III

Front 12

Severe nodulcystic, deep inflammatory, open and closed comedones, papules/pustules, extensive nodules, variable degree of scarring

Back 12

Grade IV

Front 13

Testing serum DHEAS can show if there is congenital _____ hyperplasia or a tumor of the _____ gland

Back 13

adrenal
adrenal

Front 14

middle aged and fair-skinned person –lesions are never
comedonalbut rather papulopustular and clustered over the cheeks, nose,
forehead and chin

Back 14

Acne Rosacea

Front 15

rare can occur after long-term
treatment with oral antibiotics. May have increased carrier rate of gram-
negative bacteria in the anterior nares and may develop sudden onset
of superficial pustules around the nose, chin and cheeks

Back 15

Gram negative folliculitis

Front 16

primarily in young women and adolescents
erythema, scaling and papulopustular lesions around the nasolabial folds
mouth and chin --cause is unknown - treat with antibiotics.

Back 16

Perioral dermatitis

Front 17

topical or oral corticosteroid therapy causes
lesions develop within 2 – 5 weeks of therapy - uniform in size
flesh colored pink or red.

Back 17

steroid-induced acne

Front 18

Grade I/II Tx (Superficial, noninflammatory/inflammatory):
Topical ______
Topical _____ ____ products
Physicial extraction

Back 18

retinoid
benzyl peroxide

Front 19

Grade III Tx:
First line:
topical _____
oral ______
second line:
Women: ?
Benzoyl peroxide
Intralesional corticosteroid injections

Back 19

retinoid
antibiotics
hormone therapy

Front 20

Grade IV Tx:
First line:
Oral _______
Women: ?
Second line:
Intralesional _____ injections
incision and drainage

Back 20

Isotretinoin
Oral contraceptives
corticosteroid

Front 21

Use _____ for dry skin type
____ for oily skin type
_____ for any skin type
______ work best with oily skin

Back 21

creams
gels
lotions
solutions

Front 22

Salicylic acid, retinoids, and chemical irritants are all considered what?

Back 22

Keratolytics

Front 23

This alters keratinization and decreases stickiness in the cells

Back 23

retinoids

Front 24

Azelaic acid ,benzoyl peroxide, and topical antibiotics all do what?

Back 24

Inhibit the growth of P. acnes

Front 25

Azelaic acid, Adapalene, and Tazarotene all do what?

Back 25

SUPPRESS INFLAMMATION

Front 26

_______ is the only med to suppress acne over long term, works on all four factors, category X drug
Must test CBC, ___ function tests, ______ for baseline

Back 26

Isotretinoin
liver
triglycerides

Front 27

Rhynophyma and Ocular complications are symptoms of what?

Back 27

Acne Rosacea

Front 28

Clinical features of Acne Rosacea:
Papules and pustules on broad base of erythema and _______
Central third of face sapring lateral aspects of forehead and cheeks

Back 28

telangiectasia

Front 29

Atopic Dermatitis:
Chronic, pruritic eczematous condition of the skin that is associated with a personal or family history of ____ disease (such as what?)
Etiology unknown

Back 29

atopic
asthma, allergic rhinitis

Front 30

______ areas more common for recurrent atopic dermatitis in kids/adults
Papular atopic dermatitis of the ____ more common in adul;ts

Back 30

flexural
butt

Front 31

Anything that increases ___ levels (allergens) will not cause, but aggrevate AD

Back 31

IgE

Front 32

Tx for AD
Cutaneous _____
Topical _______
Identify and eliminate flare factors
Protopic (Tacrolimus) - inhibits _____ activation by preventing early cytokines (cream)
Elidel (pimecrolimus) - calcineurin _____

Back 32

hydration
glucocorticoid
T-cell
inhibitor

Front 33

Tx of Pruritis associated with AD?

Back 33

Antihistamines
Tar preparations

Front 34

Complications of AD:
______ scarring, cataracts
Infections (esp _____)
hand dermatitis aggrevated by _____
Exfoliative dermatitis - generalized redness, scaling, weeping, crusting, lymphadenopathy and fever (rare)

Back 34

corneal
herpes simplex
soaps

Front 35

Spontaneous resolution after age 5, most outgrow by adolescence.
Poor prognosis:
Wides spread in ______, associated allergic _____ or asthma, early age of onset and which gender?, family hx

Back 35

childhood
rhinitis
female

Front 36

Contact dermatitis can be what 2 types?

Back 36

Irritant (direct toxic effect)
Allergic (immunologic reaction - type IV)

Front 37

Acute dermatitis is associated with _____ streaks of ____
Chronic dermatitis is associated with _______ of the skin, eczematous reaction

Back 37

linear
vesicles
lichenification

Front 38

Chronic, superficial inflammatory process affecting the hairy regions of the body. Infants and adults. One of the most common skin manifestations in pts with HIV

Back 38

Seborrhiec Dermatitis

Front 39

Which dermatitis is associated with Parkinson's disease? Also oily looking skin, but not a disease of the sebaceous gland

Back 39

Seborrheic Dermatitis

Front 40

Infantile Seborrheic Dermatitis is the _____ cap, trunk, Leiner's disease (______ 5 dysfunction)
Adults - scalp, face, trunk, ______ plaques, generalized

Back 40

cradle
complement
eczematous

Front 41

When dermatitis affects solely the diaper area and the axilla it is usually what dermatitis?

Back 41

Seborrheic

Front 42

What do these drugs have in common?
Arsenic, gold, methyldopa, cimetidine, neuroleptics

Back 42

Cause seborrheic dermatitis-like lesions

Front 43

Seborrheic dermatitis associated with ______ abnormalities like Parkinson, facial paralysis, poliomyelitis, quadriplegia, epilepsy

Back 43

neurologic

Front 44

Tx - loosening and removal of ____ and ____
inhibition of yeast colonization
control of secondary _____
reduction of erythema and itching
CONTROL rather than CURE

Back 44

scales
crusts (use salicylic acid in olive oil)
infection

Front 45

Infant tx of SD
Drying lotions
Candidiasis - _____ cream
Gentian _____ if oozing

Back 45

nystatin
violet

Front 46

Tx of Chronic Adult SD:
Anti-inflammatory
Anti-_____
Kerolytics
Low potency _______
Metrogel
avoid greasy ointments, strong soaps, hair tinctures
______ are the strongest, _____ weakest

Back 46

fungal
glucocorticoids
ointments strongest, lotions weakest