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24 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Depression |
- need 5 of 9 sx for diagnosis - tx trial 6-8 or 8-12 weeks - physical inc before mental, so inc risk of suicide - St. John's or SAMe "likely effective" (Natural Medicines Database) |
tx strategy: 1- inc dose 2- try combination (careful of Serotonin Syndrome) 3- augment with buspirone (BuSpar) or atypicals 4- augment with lithium, thyroid hormone, ECT 5- 2012 trial supports ketamine for further study |
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Prozac |
fluoxetine SSRI |
qAM 5 wk washout (longest t1/2) |
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Paxil |
paroxetine SSRI |
2 wk washout -- requires the longest tapering |
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Brisdelle |
paroxetine new formulation SSRI |
preg category X |
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Zoloft |
sertraline SSRI |
1ST CHOICE in cardiac pt 2 wk washout |
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Celexa |
citalopram SSRI |
AVOID in cardiac pt 2 wk washout |
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Lexapro |
escitalopram SSRI |
2 wk washout |
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Effexor |
venlafaxine SNRI |
inc BP risk esp. |
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Cymbalta |
duloxetine SNRI |
inc BP risk |
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Pristiq |
desvenlafaxine SNRI |
inc BP risk |
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Elavil |
amitriptyline TCA: NE & 5HT reuptake inh, block ACh & H receptors |
ACh blocker: constipation, dry eyes, difficulty urinating, dry mouth |
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Pamelor |
nortriptyline TCA: NE & 5HT reuptake inh, block ACh & H receptors |
ACh blocker: constipation, dry eyes, difficulty urinating, dry mouth |
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Silenor |
doxepin TCA: NE & 5HT reuptake inh, block ACh & H receptors |
ACh blocker: constipation, dry eyes, difficulty urinating, dry mouth |
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Marplan |
isocarboxazid MAOi: prevent breakdown of 5HT, NE, EPI, DA |
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Nardil |
phenylzine MAOi: prevent breakdown of 5HT, NE, EPI, DA |
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Parnate |
tranylcypromine MAOi: prevent breakdown of 5HT, NE, EPI, DA |
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Wellbutrin |
bupropion DA & NE reuptake inh |
do not use in seizure hx fewest sex SE |
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Zyban |
bupropion DA & NE reuptake inh smoking cess |
do not use in seizure hx fewest sex SE |
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Remeron |
mirtazapine DA & NE reuptake inh + TCA, blocker of alpha2, H, M |
usually used to inc appetite |
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Oleptro |
trazodone DA & NE reuptake inh |
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Abilify |
aripiprazole atypicals for therapy resistant depression only |
augment with low dose |
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Symbyax |
olanzapine / fluoxetine atypicals for therapy resistant depression only |
augment with low dose |
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Seroquel |
quetiapine atypicals for therapy resistant depression only |
augment with low dose |
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BuSpar |
buspirone 5HT partial agonist for GAD |
augment in depression |
