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29 Cards in this Set
- Front
- Back
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Depression symptoms |
physical: headache, aches |
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depression effects are |
Negative |
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check ?(major) |
mPET is low |
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major(clinic) has no |
up and down, instead just down second tenth of life |
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minor check? |
no pet... they are just sad not sick
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bipolar disorder |
mania and they dont even know |
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mania is for |
1 to 2 weeks |
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after mania comes |
depression |
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depression is assiociated with 3 paths |
serotinin,noradrenaline,dopamine |
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depression is located in the |
meso limbic! |
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genetic? |
yes but complex (schizophrenia+bipolar) |
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brain? anatomically? |
hypocampus is smaller frontal lobes |
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aminergic theory |
we need more amines...in the synapse still cocaine and aphitamines dont help us |
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depression drugs |
mao inhibitors+TCA>SSRI (BUT more side effects)
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MAO a side effect |
HBP because of tyramine. |
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MAOa words on |
NE and serotonin thats why its important |
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first generation |
not selective to mao(a) unlike second |
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Maob |
inhibts dopamine break which is good but not as good as mao a |
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Moclobemide |
compete with tyramine ( second generation) |
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TCA |
pramines (not selective) |
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what blocks NA |
2ndary amines maprotiline desipramine protriptyline |
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what blocks serotnin |
tertiary aminse citalopram |
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SSRI |
Prozac(suicide tho) |
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Mania During attack drug |
antipsychotic(haloperidol/reserpine/olanzepine) |
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to prevent future mania attack |
lithium carbonate
mania+depression |
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lithium side effects |
thirsty all the time more TSH arthmia it binds to sodium channel(ttx block them) |
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lithium in the membrane |
blocks pip2 recycle pkc plc less mioenozitol less
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lithium pharmacokinetcs(memorize) |
diuretics(reabsorption of lithium) less Na+ absorption
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anti epilpesy drugs for mania |
carbazepine gabapentin just like lithium |
