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14 Cards in this Set
- Front
- Back
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Levodopa
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most effective, 1-3% gets to brain. Nausea, orthostatic hypotension
-MAOIs bad – hypertensive crisis (phenylzine and tranylcypromine) -MAO-B ok to use (selegiline) |
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Carbidopa
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increases effectiveness of levodopa (10% to brain). (25/100 mgs carb/levo)
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Bromocriptine
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dopamine receptor agonist (agonist at D1, partial antag at D2)
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Pergolide
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dopamine receptor agonist (agonist at D1 and D2)
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Ropinirole
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dopamine receptor agonist (D2)
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Pramipexole
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dopamine receptor agonist (D2 receptors)
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Apomorphine
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administered SC. Emetogenic. Give oral trimethobenzamide before administering
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Tolcapone
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COMT inhibitor. Nausea, orthostatic hypotension, hepatotoxicity
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Entacapone
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COMT inhibitor. Nausea, ortho-hypo
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Selegline
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MAO-B inhibitor (most of oxidative metabolism of dopamine in brain), OK to take with levodopa
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Trihexyphenidyl
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muscarinic receptor antagonist
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Benzotrine mesylate
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muscarinic receptor antagonist
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Diphenhydramine HCl
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muscarinic receptor antagonist
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Amantadine
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antiviral agent used for prophylaxis
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