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10 Cards in this Set
- Front
- Back
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Give the trade name, common uses, mechanism of action, and mode of administration of ipratropium.
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Atrovent. It is used for bronchial asthma and taken by inhalation. It works by blocking muscarinic receptors (like atropine) but doesn't enter circulation. This directly decreases bronchial muscle tone.
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Give the trade name, common uses, mechanism of action, and mode of administration of hyoscyamine.
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Anaspaz. It is the pure active isomer of atropine. It is used in dentistry to decrease salivation. It is the prototype antimuscarinic.
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Give the trade name, common uses, mechanism of action, and mode of administration of Scopolamine.
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Scopace or Transderm-Scop. It is used to treat motion sickness in patch form. It is also used to treat Meniere's disease by stopping inappropriate information from the inner ear. It is an antimuscarinic.
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Give the trade name, common uses, mechanism of action, and mode of administration of Glycopyrrolate.
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Robinul. It is used to decrease secretions. Antimuscarinic, but does not cross BBB because it's a quaternary ammonium compound. Given by IV or intramuscular.
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Give the trade name, common uses, mechanism of action, and mode of administration of Propantheline.
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Pro-Banthine. Blocks secretions. Anti-muscarinic. In pill form to treat ulcers. Anti-muscarinic, so it has all the effects of other anti-muscarinic quaternary ammonium compounds.
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Give the trade name, common uses, mechanism of action, and mode of administration of Benztropine. Also give site of action.
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Cogentin. Intramuscular or IV antimuscarinic. Used against Parkinson's disease because it acts centrally and not peripherally.
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Give the trade name, common uses, mechanism of action, and mode of administration of tolterodine.
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Detrol. Used to prevent accidental urination. Anti-muscarinic, so prevent contraction of detrusor muscle of bladder. Taken orally.
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What are the contraindications of anti-muscarinics?
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Angle-closure glaucoma, obstructive GI or GU disease, Myasthenia gravis, prostatic hypertrophy (because urination can be very difficult)
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What are the common side effects of anti-muscarinics?
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Xerostomia, hyperthermia in children (because it prevents sweating), tachycardia (with atropine), sedation and confusion (scopolamine), mydriasis, cycloplegia (paralysis of ciliary muscle of eye).
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Give the trade name, common uses, mechanism of action, and mode of administration of physostigmine.
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Eserine. It is used to treat atropine overdose. It may also be used to treat glaucoma. It is given by IV or intramuscular.
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