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104 Cards in this Set

  • Front
  • Back

Embryology

the study of prenatal development (from fertilization of an egg to birth)

Meiosis

process of reproductive cell production that ensures the correct # of chromosomes


Mitosis

individual cells divide resulting in 2 daughter cells that are identical to parent cells


Blastocysts

aggregate of mitotically produced cells

Growth

increase in size and weight, growth requires an increase in the number of cells, the size of cells and the products of the cells

Development

increase in complexity and organization towards ta final form

Teratogens

"monster producing"


Primordium

the earliest indication of a part of organ

Zygote

fertilized egg


Preimplantation period

takes place during the first week after conception

implantation

embedded in the prepare endometrium, the innermost lining of the uterus on the back wall

ectopic pregnancy

implantation occurs outside the uterus, most commonly in the fallopian tube

Fertilization

union of ovum and sperm to form zygote


Ovum and sperm individually contain 23 chromosomes-- haploid

Meiosis

occurs in the gonads resulting in a haploid # of chromosomes

Mitosis

Individual cells of the zygote go through cell division --of thier 46 chromosomes

Blstocyst Formation

5th day.


Trophoblas


Embyoblast

Trophoblast:

layer of peripheral cells (will become supportive tissues)

Embryoblast

inner mass of cells that develops into the embryo


6-7th day

implantation of the blastocyst into the endometrial lining

Embyonic Period

2nd week - end of 8th week

proliferation

follows induction control levels of cellular growth present during most of prenatal develplement

interstitial growth

occurs from deep within tissue type or organ.

appositional growth

tissue enlarges by the addition of layers on the outside of a structure

differentation

a change occurs in the embryonic cell, which are identical genetically but later become quite distinct structurally and functionally. (cells that perform specialized functions are formed by differentation during embryonic period

Second Week

Embryonic stage


the implanted blastocyst grows by increased proliferation of the embryonic cells, with differentation also occuring reulting in changes in cell morphology. creating embryonic cell layer

Third Week

Primitive streak fomrs within the bilaminar disc. this causes the disc to have bilateral symmetry (half the embryo mirrors the other half).


-Mesoderm


-Ectoderm


-Endoderm developes


Nural tube, grooves, head and "tail" form


Fourth Week


The disc undergoes embryonic folding


foregut, midgut, hindgut form. Primitive face starts to develop

Primitive streaks

the bilaminar disk is divided by this streak formed by the proiferation of cells at the midline

Mesemchymal cells

embryoic connective tissue forms CT forming cells: fibroblasts, chondroblasts, osteoblasts, etc.

Epiblast

ectoderm (epidermis, nervous system)


Mesenchyme

Mesoderm (CT, muscles, vessels, etc)

Hypoblast

endoderm (epithelial lining of the GI and respiratory system

Formation of the Cephalic

Head--


at teh cephalic end there is an oropharyngeal membrane that only contains endo and ectoderm. this will be the future mouth and GI tract

Formation of the Caudal end

at the caudal end ther is a cloacal membrane. this membrane lacks mesoderm as well (like the cephalic end)

Neuroectoderm cells differentiate from:

ectoderm

neuroectoderm cells make up the:

Neural plate

Neural plate begins to navigate and form the

Neural groove

Neural Fold

further invagination of the nueral plate produces these at crest of neural plate

neural crest cells

formed from the neuroectoderm these cells break off from the neural folds and are disperesed in the mesenchyme

Neural crest cells form:

parts of the face and neck structures and oral tissues. --many embryologists consider this the 4th embryonic layer

Neural Tube forms:

neural folds fuse, to make the future spinal cord

Embryonic folding

results in a tubular embryo, now the endoderm lies inside the ectoderm

Foregut

Anterior part of the tube, which forms the primitive pharynx

Midgut and Hindgut

Posterior parts of the tube form the rest of the mature pharynx and remainder of the digestive tract

Palatal Development occurs in the:

occurs in the 5 week


The intermaxiallary segment/premaxillary segment forms:

Fusion of the two medial nasal processes.


this segment gives rise to the primary palate.


what forms the anterior 1/3 of the hard palate?

anterior to the incisile foramen


maxillary incisors

When does Secondary palate formation take place?

6th week

the maxillary processes give rise to 2 palatal shelves "lateral palatine processes"

-they grow inferior and deep in a vertical direction


-processes "flip" and move horizontal and grow medially towards each other.


-Forms post 2/3 of hard palate, soft palate, and uvula

When does the completion of palate formation occur?

12th week

what happens during the 12th week?

-Fusion of all 3 processes


-Seperation of oral and nasal cavities is complete


-mesenchyme from the 1st and 2nd branhial arches migrates to te soft palate and forms te palatal muscles


-cleft palate may occur.

When does tongue development happen?

4-8 weeks

how is the tongue formed?

-formed from the 1st branchial arch


-tuberculum impar: triangular median swelling, located on the floor of the promitive pharynx


-lateral lingual swellings develop just lateral to the tuberculum impar

Anterior portion of the endodermal tube forms the...

primitive pharynx

the caudal portion forms the...

esophagus

what forms below the oropharynx and to the ventral surface, what forms.?

laryngopharynx, larynx, trachea, the superior portion of the lungs, and the thyroid gland form.


1st branchial pouches form the...

Auditory tubes

2nd branchial pouches form the...

palatine tonsils

3rd and 4th branchial pouches form the...

thymus and parathyroid glands

5 major processes of the face....

1. Stomodeum /oral cavity


2.Mandibular processes


3. Maillary processes


4. Frontonasal/upper face


5. Development of the neck

Types of Fusion

1. Facial Fusion -same surface


2. Palatal Fusion -different surfaces fuse


when does the formation of the stomodeum form?

3rd week

the ectoderm invagginates at the ventral side fo the embryo until it comes into contact with...

the foregut

the union of the ectoderm and the endoderm form the...

buccopharyngeal/oropharyngeal membrane (temporary membrane)


Process of formation of the stomodeum:

1. The ectoderm invaginates at the ventral side of the embryo until it comes into contact with the foregut


2. The union of the ectoderm and endoderm form the buccopharyngeal/oropharyngeal membrane


3. At the 4th week the membrane ruptures allowing direct contact, making an open GI track.


4. At the rear of the stomodeum Raphe's pouch will extend into the cephalic area and separate from the stomodeum, forming the anterior lobe of the pituitary gland

mandibular arch and lower face formation occurs at what week?

4th

which branchial arch is the mandibular arch considered?

1st

the madibular arch gives rise to:

1. Lower face (lower lip)


2. Mandible


3. Ligaments of the jaw and middle ear


4. Muscles of mastication


5. tongue


6. maxillary processes

Meckel's cartilage:

cartilage formed within each side of the mandibular arch.


-part goes to middle ear bones,


- part becomes ligaments of the jaw and middle ear.


when does the mesoderm of mandibular arch forms future muscles of mastication?

week 5-10

the maxillary process and midface are formed from...

swelling from the mandibular arch

where does the maxillary process grow in relation to the stomodeum?

superiourly and anteriorly on each side of the stomodeum.

The maxillary process gives rise to the midface which include...

Sides of the upper lip, cheeks, secondary palate, posterior portion of the maxilla, maxillary canines and posterior teeth, zygomatic bones and portions of the temporal bones.

what forms labial commissures?

maxillary process partially fuses with the mandibular arch to form the labial commissures

Macrostomia

cleft at the commissures, (incomplete fusion) makes mouth huge

What week does the formation of the frontonasal process and upper face begin?

4th week

a bulge of tissue at the most cephalic end will give rise to...

Upper face


-forehead, bridge of nose, primary palate, nasal septum.


Philtrum


-anterior part of hard plate


-medial nasal processes

Placode:

rounded areas of ectoderm tissue, location of special sense organs.

Lens placodes:

on each side of the frontonasal process, later they will migrate medially and form the future eyes and related tissues.

Otic placodes

even more lateral and posterior, pits that will form the future internal ear.

Nasal placodes:

form just superior to the stomodeum, later develop into olfactory cells

oronasal membrane

separates the nasal sac from the stomodeum, once this disintegrates the oral and nasal membranes are in communication

medial nasal processes

crescent shaped swelling around the placodes, this will fuse and form the middle portion of the nose, the philtrum and tubercle


-internally these processes fuse to form the intermaxillary segment

Intermaxillary segment/ premaxilla

forms from the medial nasal processes


--Maxillary incisors & associated tissues, primary palate, and nasal septum

Lateral nasal process

later form the alae.


--fusion of the lateral nasal processes, medial nasal processes, and maxillary process form the nares

Explain upper lip formation

Formed by the joining of the maxillary process and the 2 medial nasal processes


-starts in 4th week and is completed during the 6th week

Explain Lacrimal tissue formation

-Nasolacrimal groove extends from the medial corner of the eye to the nasal cavity


-Nasolacrimal cord: ectodermal thickening in the floor of the nasolacrimal groove. this forms the lacrimal sac of the eye and becomes the nasolacrimal duct.

cleft lip is more common in...

Boys

cleft palate is more common in...

girls

what forms the primitive pharynx?

Anterior portion of the enodermal tube (foregut) forms the primitive pharynx

what forms the esophagus?

Caudal (posterior) portion

Where does the Larynx, laryngopharynx, trachea, superior portions of the lungs and thyroid gland form?

below the oropharynx and to the ventral surface

1st Branchial arch:

Mandibular arch, forms the lower and middle portions of the face.

2nd Branchial arch:

-Hyoid arch


-Reichert's cartilage (forms middle ear bone, temporal and part of hyoid bone)


-innervated by the 7th cranial nerve (facial)


-muscles of facvial expression are derived from the mesoderm of this arch


-involved with tongue formation


3rd Branchial arch:

-Forms portions of hyoid bone


-pharyngeal muscles are formed from the mesoderm


-innervated by the 9th cranial nerve (glossopharyngeal)


-helps with formation of tongue


4th and 6th Branchial arch:

-Forms Laryngeal cartilage


-mesoderm forms the muscles of the laynx and pharynx


-innervated by 9th and 10th nerves (vagus)


-helps in formation of tongue


Branchial grooves located:

between the developing branchial arches

1 branchial groove forms:

the external auditory meatus

What happens to all the inferior Branchial grooves?

the obliteration of all the other grooves gives the neck a smooth contour

Pharyngeal (branchial) pouches

develop between the branchial arches (internally)

1st pharygeal pouch forms the:

auditory tubes

2nd pharyngeal pouch forms:

palatine tonsils

3rd and 4th pharyngeal pouch form:

thymus and parathyroid glands

what cartilage is developed in the first brancial arch?


Second branchial arch?

first: Meckel's cartilage


second: Reichert's cartilage