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104 Cards in this Set
- Front
- Back
Embryology |
the study of prenatal development (from fertilization of an egg to birth) |
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Meiosis |
process of reproductive cell production that ensures the correct # of chromosomes
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Mitosis |
individual cells divide resulting in 2 daughter cells that are identical to parent cells
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Blastocysts |
aggregate of mitotically produced cells |
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Growth |
increase in size and weight, growth requires an increase in the number of cells, the size of cells and the products of the cells |
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Development |
increase in complexity and organization towards ta final form |
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Teratogens |
"monster producing"
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Primordium |
the earliest indication of a part of organ |
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Zygote |
fertilized egg
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Preimplantation period |
takes place during the first week after conception |
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implantation |
embedded in the prepare endometrium, the innermost lining of the uterus on the back wall |
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ectopic pregnancy |
implantation occurs outside the uterus, most commonly in the fallopian tube |
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Fertilization |
union of ovum and sperm to form zygote Ovum and sperm individually contain 23 chromosomes-- haploid |
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Meiosis |
occurs in the gonads resulting in a haploid # of chromosomes |
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Mitosis |
Individual cells of the zygote go through cell division --of thier 46 chromosomes |
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Blstocyst Formation |
5th day. Trophoblas Embyoblast |
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Trophoblast: |
layer of peripheral cells (will become supportive tissues) |
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Embryoblast |
inner mass of cells that develops into the embryo
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6-7th day |
implantation of the blastocyst into the endometrial lining |
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Embyonic Period |
2nd week - end of 8th week |
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proliferation |
follows induction control levels of cellular growth present during most of prenatal develplement |
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interstitial growth |
occurs from deep within tissue type or organ. |
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appositional growth |
tissue enlarges by the addition of layers on the outside of a structure |
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differentation |
a change occurs in the embryonic cell, which are identical genetically but later become quite distinct structurally and functionally. (cells that perform specialized functions are formed by differentation during embryonic period |
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Second Week |
Embryonic stage the implanted blastocyst grows by increased proliferation of the embryonic cells, with differentation also occuring reulting in changes in cell morphology. creating embryonic cell layer |
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Third Week |
Primitive streak fomrs within the bilaminar disc. this causes the disc to have bilateral symmetry (half the embryo mirrors the other half). -Mesoderm -Ectoderm -Endoderm developes Nural tube, grooves, head and "tail" form
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Fourth Week |
The disc undergoes embryonic folding foregut, midgut, hindgut form. Primitive face starts to develop |
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Primitive streaks |
the bilaminar disk is divided by this streak formed by the proiferation of cells at the midline |
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Mesemchymal cells |
embryoic connective tissue forms CT forming cells: fibroblasts, chondroblasts, osteoblasts, etc. |
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Epiblast |
ectoderm (epidermis, nervous system)
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Mesenchyme |
Mesoderm (CT, muscles, vessels, etc) |
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Hypoblast |
endoderm (epithelial lining of the GI and respiratory system |
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Formation of the Cephalic |
Head-- at teh cephalic end there is an oropharyngeal membrane that only contains endo and ectoderm. this will be the future mouth and GI tract |
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Formation of the Caudal end |
at the caudal end ther is a cloacal membrane. this membrane lacks mesoderm as well (like the cephalic end) |
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Neuroectoderm cells differentiate from: |
ectoderm |
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neuroectoderm cells make up the: |
Neural plate |
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Neural plate begins to navigate and form the |
Neural groove |
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Neural Fold |
further invagination of the nueral plate produces these at crest of neural plate |
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neural crest cells |
formed from the neuroectoderm these cells break off from the neural folds and are disperesed in the mesenchyme |
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Neural crest cells form: |
parts of the face and neck structures and oral tissues. --many embryologists consider this the 4th embryonic layer |
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Neural Tube forms: |
neural folds fuse, to make the future spinal cord |
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Embryonic folding |
results in a tubular embryo, now the endoderm lies inside the ectoderm |
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Foregut |
Anterior part of the tube, which forms the primitive pharynx |
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Midgut and Hindgut |
Posterior parts of the tube form the rest of the mature pharynx and remainder of the digestive tract |
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Palatal Development occurs in the: |
occurs in the 5 week
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The intermaxiallary segment/premaxillary segment forms: |
Fusion of the two medial nasal processes. this segment gives rise to the primary palate.
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what forms the anterior 1/3 of the hard palate? |
anterior to the incisile foramen maxillary incisors |
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When does Secondary palate formation take place? |
6th week |
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the maxillary processes give rise to 2 palatal shelves "lateral palatine processes" |
-they grow inferior and deep in a vertical direction -processes "flip" and move horizontal and grow medially towards each other. -Forms post 2/3 of hard palate, soft palate, and uvula |
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When does the completion of palate formation occur? |
12th week |
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what happens during the 12th week? |
-Fusion of all 3 processes -Seperation of oral and nasal cavities is complete -mesenchyme from the 1st and 2nd branhial arches migrates to te soft palate and forms te palatal muscles -cleft palate may occur. |
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When does tongue development happen? |
4-8 weeks |
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how is the tongue formed? |
-formed from the 1st branchial arch -tuberculum impar: triangular median swelling, located on the floor of the promitive pharynx -lateral lingual swellings develop just lateral to the tuberculum impar |
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Anterior portion of the endodermal tube forms the... |
primitive pharynx |
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the caudal portion forms the... |
esophagus |
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what forms below the oropharynx and to the ventral surface, what forms.? |
laryngopharynx, larynx, trachea, the superior portion of the lungs, and the thyroid gland form.
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1st branchial pouches form the... |
Auditory tubes |
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2nd branchial pouches form the... |
palatine tonsils |
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3rd and 4th branchial pouches form the... |
thymus and parathyroid glands |
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5 major processes of the face.... |
1. Stomodeum /oral cavity 2.Mandibular processes 3. Maillary processes 4. Frontonasal/upper face 5. Development of the neck |
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Types of Fusion |
1. Facial Fusion -same surface 2. Palatal Fusion -different surfaces fuse
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when does the formation of the stomodeum form? |
3rd week |
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the ectoderm invagginates at the ventral side fo the embryo until it comes into contact with... |
the foregut |
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the union of the ectoderm and the endoderm form the... |
buccopharyngeal/oropharyngeal membrane (temporary membrane)
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Process of formation of the stomodeum: |
1. The ectoderm invaginates at the ventral side of the embryo until it comes into contact with the foregut 2. The union of the ectoderm and endoderm form the buccopharyngeal/oropharyngeal membrane 3. At the 4th week the membrane ruptures allowing direct contact, making an open GI track. 4. At the rear of the stomodeum Raphe's pouch will extend into the cephalic area and separate from the stomodeum, forming the anterior lobe of the pituitary gland |
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mandibular arch and lower face formation occurs at what week? |
4th |
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which branchial arch is the mandibular arch considered? |
1st |
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the madibular arch gives rise to: |
1. Lower face (lower lip) 2. Mandible 3. Ligaments of the jaw and middle ear 4. Muscles of mastication 5. tongue 6. maxillary processes |
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Meckel's cartilage: |
cartilage formed within each side of the mandibular arch. -part goes to middle ear bones, - part becomes ligaments of the jaw and middle ear.
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when does the mesoderm of mandibular arch forms future muscles of mastication? |
week 5-10 |
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the maxillary process and midface are formed from... |
swelling from the mandibular arch |
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where does the maxillary process grow in relation to the stomodeum? |
superiourly and anteriorly on each side of the stomodeum. |
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The maxillary process gives rise to the midface which include... |
Sides of the upper lip, cheeks, secondary palate, posterior portion of the maxilla, maxillary canines and posterior teeth, zygomatic bones and portions of the temporal bones. |
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what forms labial commissures? |
maxillary process partially fuses with the mandibular arch to form the labial commissures |
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Macrostomia |
cleft at the commissures, (incomplete fusion) makes mouth huge |
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What week does the formation of the frontonasal process and upper face begin? |
4th week |
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a bulge of tissue at the most cephalic end will give rise to... |
Upper face -forehead, bridge of nose, primary palate, nasal septum. Philtrum -anterior part of hard plate -medial nasal processes |
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Placode: |
rounded areas of ectoderm tissue, location of special sense organs. |
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Lens placodes: |
on each side of the frontonasal process, later they will migrate medially and form the future eyes and related tissues. |
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Otic placodes |
even more lateral and posterior, pits that will form the future internal ear. |
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Nasal placodes: |
form just superior to the stomodeum, later develop into olfactory cells |
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oronasal membrane |
separates the nasal sac from the stomodeum, once this disintegrates the oral and nasal membranes are in communication |
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medial nasal processes |
crescent shaped swelling around the placodes, this will fuse and form the middle portion of the nose, the philtrum and tubercle -internally these processes fuse to form the intermaxillary segment |
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Intermaxillary segment/ premaxilla |
forms from the medial nasal processes --Maxillary incisors & associated tissues, primary palate, and nasal septum |
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Lateral nasal process |
later form the alae. --fusion of the lateral nasal processes, medial nasal processes, and maxillary process form the nares |
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Explain upper lip formation |
Formed by the joining of the maxillary process and the 2 medial nasal processes -starts in 4th week and is completed during the 6th week |
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Explain Lacrimal tissue formation |
-Nasolacrimal groove extends from the medial corner of the eye to the nasal cavity -Nasolacrimal cord: ectodermal thickening in the floor of the nasolacrimal groove. this forms the lacrimal sac of the eye and becomes the nasolacrimal duct. |
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cleft lip is more common in... |
Boys |
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cleft palate is more common in... |
girls |
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what forms the primitive pharynx? |
Anterior portion of the enodermal tube (foregut) forms the primitive pharynx |
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what forms the esophagus? |
Caudal (posterior) portion |
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Where does the Larynx, laryngopharynx, trachea, superior portions of the lungs and thyroid gland form? |
below the oropharynx and to the ventral surface |
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1st Branchial arch: |
Mandibular arch, forms the lower and middle portions of the face. |
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2nd Branchial arch: |
-Hyoid arch -Reichert's cartilage (forms middle ear bone, temporal and part of hyoid bone) -innervated by the 7th cranial nerve (facial) -muscles of facvial expression are derived from the mesoderm of this arch -involved with tongue formation
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3rd Branchial arch: |
-Forms portions of hyoid bone -pharyngeal muscles are formed from the mesoderm -innervated by the 9th cranial nerve (glossopharyngeal) -helps with formation of tongue
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4th and 6th Branchial arch: |
-Forms Laryngeal cartilage -mesoderm forms the muscles of the laynx and pharynx -innervated by 9th and 10th nerves (vagus) -helps in formation of tongue
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Branchial grooves located: |
between the developing branchial arches |
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1 branchial groove forms: |
the external auditory meatus |
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What happens to all the inferior Branchial grooves? |
the obliteration of all the other grooves gives the neck a smooth contour |
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Pharyngeal (branchial) pouches |
develop between the branchial arches (internally) |
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1st pharygeal pouch forms the: |
auditory tubes |
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2nd pharyngeal pouch forms: |
palatine tonsils |
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3rd and 4th pharyngeal pouch form: |
thymus and parathyroid glands |
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what cartilage is developed in the first brancial arch? Second branchial arch? |
first: Meckel's cartilage second: Reichert's cartilage |