Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
14 Cards in this Set
- Front
- Back
|
all isomerases have
|
a cis-enediol intermediate
|
|
|
all dehydrogenase indicate
|
NAD+ or NADP is involved
|
|
|
Aldolase requires _______ residue
|
Lysine ~~~> Schiff Base
|
|
|
Phosphoglycerate mutase requires
|
histidine
- gets phosphorylated |
|
|
Cofactors are needed by
|
enzymes for proper function
|
|
|
What are the cofactors are in glycolysis?
|
Mg 2+
|
|
|
Fermination
Pyruvate ~~~~~> Ethanol via.... Cofactor? |
pyruvate decarboxylase
Cofactor: TTP |
|
|
Gluconeogenesis is?
Cofactor? |
regenerate/reverse from pyruvate to glucose
- Cofactor: Biotin |
|
|
Biotin does what?
|
it's a cofactor for glucogenesis
Biotin takes carbons and swing them down to make closer to chemical structure |
|
|
What is of Galactosemia?
|
Defects of any of the three enzymes in the galacose pathway results in galactosemia in human
|
|
|
3 Effects of Galactosemia?
|
- Galactose kinase defect
- UTD defect - epimerase deficiency |
|
|
What is the effect of Galactose kinase defect & treatment
|
- HIgh gal. concentrations in blood and urine
- Cataracts are developed because the galactose in converted to galacitol which is deposited in the lens - treatment Limit galactose in diet |
|
|
What is the effect of UTD defect
|
- more seroius then Gala. kinase defect.
- poor growth in children, speech abnormality, mental deficiency, and liver damage. -removing gal in diet may not help |
|
|
What is the effect of epimerase deficiency
|
- similar to UTD but less severe
|
