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19 Cards in this Set
- Front
- Back
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Glycogen Breakdown:
Phosphorylase is |
Removal of a terminal glucose residue from the nonreducingend of a glycogen chain by glycogen phosphorylase.
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Glycogen Breakdown:
The Phosphorylase process is |
repetitive
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Glycogen Breakdown:
In the Phosphorylase process the enzyme removes? |
removes successive glucose residues until the fourth glucose unit from the branch point.
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Glycogen Breakdown:
The product of Phosphorylase is? • |
-glucose-1-P.
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Glycogen Breakdown:
What is an essential cofactor for phosphorylase activity. • |
Pyridoxal-P
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Glycogen Breakdown:
In Pyridoxal-P, the phosphate group is? |
an acid catalyst promoting attack by Pi on the glycosidic bond.
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Glycogen Breakdown:
Pyridoxal-P is bound via a ________ to __________. |
- Schiff Base
- Lys residue 679 |
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Glycogen Breakdown:
Further degradation of glycogen occurs after ? |
debranching
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Glycogen Breakdown:
A debranching enzyme known as ............ degrades the remaining four glucose chain by transferring ............ and the glucose unit in alpha 1,6 linkage is hydrolyzed. Then phosphorylase can continue its action. |
- oligo 1,6--> 1,4 glucantransferase
- a maltotriosyl unit to a non reducing end of another glucose branch |
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Glycogen Breakdown:
A debranching enzyme known as oligo 1,6--> 1,4 glucantransferase degrades the remaining four glucose chain by transferring a maltotriosyl unit to a non reducing end of another glucose branch and the glucose unit in alpha 1,6 linkage is ...... |
hydrolyzed. Then phosphorylase can continue its action.
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Glycogen Breakdown:
Mechanism of the bifunct. debranching enzyme. Debranching is a __ __ process. |
two step
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Glycogen Breakdown:
Mechanism of the bifunct. debranching enzyme. First transferase activity on the .... |
maltotriosyl group and then alpha 1,6 glucosidase activity.
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Glycogen Breakdown:
Mechanism of the bifunct. debranching enzyme. What is the product of phosphorylase activity? |
Glucose1-P
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Glycogen Breakdown:
Mechanism of the bifunct. debranching enzyme. Glucose1-P, the product of phosphorylase activity is converted to ........ via phosphoglucomutase activity. |
glucose 6-P
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Glycogen Breakdown:
Mechanism of the bifunct. debranching enzyme. Glucose1-P, the product of phosphorylase activity is converted to glucose 6-P via ? |
phosphoglucomutase activity
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Glycogen Breakdown:
Mechanism of the bifunct. debranching enzyme. After phosphoglucomutase activity, glucose-6-P can then be metabolized either by..... or ......? |
glycolysis or the pentose-P pathway.
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Glycogen Breakdown:
Mechanism of P-glucomutase. The reaction begins with ...? |
the enzyme phosphorylated at a Ser residue.
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Glycogen Breakdown:
Mechanism of P-glucomutase. During enzyme phosphorylated at a Ser residue, The enzyme donates the phosphoryl residue to .... to form ........ |
glucose-1-P to form glucose-1,6-bisP
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Glycogen Breakdown:
Mechanism of P-glucomutase. After enzyme phosphorylated at a Ser residue and glucose-1,6-bisP is formed ,The P residue at C-1 is then transferred .... |
back to the enzyme reforming the phosphoenzyme and glucose 6-P.
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