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55 Cards in this Set
- Front
- Back
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Pyrogenic cytokines
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IL-1, IL-6, TNF-alpha
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chemotactic cytokine for neutrophils
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IL-8
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Stimulates CD4 and CD8 T cells
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IL-2
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"Snot producing" cytokine - enhances class switching to IgA, differentiation of B cells
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IL-5
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Activates endothelium to express adhesion molecules, recruites leukocytes
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IL-1
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Differentiation of T cells into Th1 cells
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IL-12
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Differentiation of T cells into Th2 cells, class switching to IgE and IgG
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IL-4
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Differentiation of bone marrow stem cells
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IL-3
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Activates macrophages and Th1 cells; suppresses Th2 cells
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IFN-gamma
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Interferons interfere with…
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viruses
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TCR, along with ___________ on T cells, allows for binding to __________ on APC's
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CD28, B7
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Helper T cells have CD4 and ___________, allowing for binding to B cells
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CD40L
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B cell receptor for EBV
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CD21
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B cell surface proteins
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CD19, CD20, CD21
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Marker unique for NK cells
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CD56
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Marker unique for Macrophages
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CD14
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Binds Fc of IgG, is found on macrophages and NK cells
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CD16
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When T cells don't have a costimulatory molecule, and are therefore nonreactive, they are said to be
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anergic
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Passive immunity given after exposure to…
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Tetanus toxin, Botulinum toxin, HBV, or Rabies virus (To Be Healed Rapidly)
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Type I hypersensitivity mechanism and test?
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anaphalyactic, scratch test
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Type II hypersensitivity mechanism and test?
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antibody mediated, direct and indirect Coombs
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Type III hypersensitivity - mechansim and test?
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Antibody-antigen-complement, immunofluorescent staining
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Type IV hypersensitivity - mechansim and test?
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T cell mediated, patch test
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Arthus reaction - what is happening and example?
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Type III reaction - swelling, inflammation following tetanus vaccine
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Bee sting
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Type I
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eczema
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Type I
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asthma
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Type I
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Hemolytic anemia
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Type II
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pernicious anemia
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Type II
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idiopathic thrombocytopenic purpura
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Type II
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erythroblastosis fetalis
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Type II
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acute hemolytic transfusion reactions
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Type II
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rheumatic fever
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Type II
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goodpasture's syndrome
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Type II
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bullous pemphigoid
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Type II
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pemphigus vulgaris
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Type II
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graves disease
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Type II
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myasthenia gravis
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Type II
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SLE
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Type III
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Rheumatoid arthritis
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Type III
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polyarteritis nodosum
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Type III
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poststreptococcal glomerulonephritis
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Type III
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serum sickness
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Type III
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hypersensitivity pneumonitis
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Type III
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Type I DM
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Type IV
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Multiple Sclerosis
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Type IV
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Guillain-Barre syndrome
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Type IV
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Hashimoto's thyroiditis
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Type IV
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Graft-versus-host disease
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Type IV
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PPD
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Type IV
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Poison ivy
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Type IV
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Nickel allergy
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Type IV
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Transplant recipient rejects transplant minutes after surgery - type and mechanism
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Type II Hypersensitivity - hyperacute rejection
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Transplant rejection weeks after transplant - type and mechanism
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Type IV hypersensitivity - acute rejection
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Mechanism of Graft-vs-Host disease?
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Graft T cells attack host cells
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