Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
28 Cards in this Set
- Front
- Back
|
Penicillin mechanism of action
|
Inhibits cell wall synthesis
Usually bactericidal |
|
|
Penicillin indication for use
|
More effective on gram+
Strep infections Strep pharangitis Rheumatic fever |
|
|
Penicillin general side effects
|
ALLERGY
GI distress Superinfections Anaphylaxis |
|
|
Penicillin education
|
Call for allergic reaction
Complete entire doses MAY DECREASE ORAL CONTRACEPTIVE MEDICATION POTENCY Do not take with acidic fluid |
|
|
Cephalosporins mechanism of action
|
Interferes with bacterial cell wall synthesis
|
|
|
Cephalosporins indications of use
|
Gram + and -
Used for skin, bone, joint, CNS, GU and respiratory tract infection |
|
|
Cephalosporins general side effects
|
GI distress
N/V Nephrotoxicity C-diff infection |
|
|
Cephalosporins education
|
Take with food
Don't take with alcohol |
|
|
Macrolides mechanism of action
|
Bacteriostatic at moderate dose
Bacetriocidal at large dose Inhibits protein synthesis |
|
|
Macrolides indications for use
|
Broad spectrum antibiotic
Okay for PCN allergy Mycoplasmal pneumonia Lagionnarie's disease whooping cough Chlamydia |
|
|
Macrolides general side effects
|
Abdominal cramps
N/V/D Hepatotoxcitiy |
|
|
Macrolides education
|
Take with food
DO NOT take with fruit juices |
|
|
Tetracycline mechanism of action
|
inhibits bacterial protein synthesis
excreted primarily in the kidneys |
|
|
Tetracycline indications for use
|
broad spectrum
gram + and - treats rocky mtn spotted fever lyme disease acne h. pylori chlamydia many gram - have developed resistance |
|
|
Tetracycline general side effects
|
N/V/D
Photosensitvity Nephrotoxicity Superinfection No pregnancy No children under 8 |
|
|
Tetracycline education
|
Don't take with milk, iron or antacids
Stay out of sun May decrease the effectiveness of oral contraception |
|
|
Aminoglycosides mechanisms of action
|
inhibits bacterial protein synthesis
injected drugs are not metabolized, excreted unchanged in urine Oral drugs are excreted in feces |
|
|
Aminoglycosides indications for use
|
Aerobic gram - (psedomonas, proteus, e-coli, klebsiella, serratia)
Urinary, GI, Respiratory Serious systemic infections |
|
|
Aminoglycosides general side effects
|
Ototoxicity
Nephrotoxicity Superinfections |
|
|
Aminoglycosides contraindications
|
Severe renal disease
Elderly Neonates |
|
|
Flouroquinolones mechanism of action
|
interferes with two bacterial enzymes which are needed for the synthesis of bacterial DNA
Metabolized in liver, excreted in kidney and feces |
|
|
Flouroquinolones indications for use
|
gram + and -
Respiratory, GI, GU, skin and soft tissue ORAL ADMINISTRATION |
|
|
Flouroquinolones general side effects
|
N/V/D
Headache Dizziness Photphobia Prolong QT interval Hepatotoxicity |
|
|
Flouroquinolones contraindications
|
renal disease
seizure disorder Affects cartilage in children No one younger than 18 |
|
|
Sulfonamides mechanism of action
|
inhibits bacterial synthesis of folic acid
Metabolized in liver and excreted in kidneys |
|
|
Sulfonamides indications for use
|
Gram - and +
UTI, OM, pneumocystitis carnii Bacteriostatic |
|
|
Sulfonamides general side effects
|
Steven-Johnson syndrome
Blood dyscrasias Nephrotoxicity Photosensitivity Kernicterus |
|
|
Sulfonamides education
|
drink 2-3 liters of water a day
NOT for children under 2 months-causes jaundice Not for pts with renal failure |
