Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
17 Cards in this Set
- Front
- Back
|
Iris nevus can be
|
circumscribed or diffuse.
|
|
|
The iris nevus color can be
|
grey, brown, tan, yellow, or white (BED).
|
|
|
Two secondary effects include
|
ectropion uveae and sectorial cataract.
|
|
|
A predisposing condition is
|
neurofibromatosis type 1.
|
|
|
The differential diagnosis includes
|
iris melanoma, ciliary body melanoma spreading to anterior chamber and freckle.
|
|
|
Assessment includes
|
slit-lamp examination, gonioscopy, color photography, high-frequency ultrasonography and, in some cases, OCT.
|
|
|
Growth of an iris nevus
|
commonly occurs in teenage years (BED).
|
|
|
Features suggestive of iris melanoma include
|
ectropion iridis, prominent vasculature, sectorial cataract, secondary glaucoma, seeding, extraocular spread, large size and documented growth.
|
|
|
The iris melanoma shape can be
|
circumscribed or diffuse (or tapioca).
|
|
|
The color of iris melanoma can be
|
white, yellow, tan, brown, grey, black, or pink.
|
|
|
Iris melanomas tend to be located
|
inferiorly.
|
|
|
Assessment includes
|
slit-lamp examination, gonioscopy, color photography, angle photographs, high-frequency ultrasonography, surveillance, biopsy.
|
|
|
Treatment methods include
|
iridectomy, iridocyclectomy, brachytherapy, proton beam radiotherapy and enucleation.
|
|
|
Metastasis predictors include
|
diffuse growth pattern, angle involvement, glaucoma.
|
|
|
The overall metastatic mortality is
|
5% at 10 years and 10% at 20 years.
|
|
|
Histological appearances of iris nevus are
|
branching dendritic or spindle cells with melanin granules in cytoplasm and no atypia.
|
|
|
Histo features of iris melanoma are
|
spindle cells with plump nuclei and/or epithelioid cells with large round nucleus, both types showing nucleoli.
|
