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56 Cards in this Set
- Front
- Back
After transplantation, Cyclosporine causes this sort of organ damage 25-38% of the time
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nephrotoxicity
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Which is safer at equipotent doses: prilocaine or lidocaine
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prilocaine
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TEG. MA value decreased. Indicates what? Treatment?
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Measures strength of fully formed clot. Platelets.
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TEG. R value decreased. Indicates what? Treatment?
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R value = Reaction time. Prolonged = coag factor abnormalities, factor deficiencies, or heparin. give FFP.
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TEG. Alpha angle decreased. Indicates what? Treatment?
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rate of clot formation |
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TEG. K value decreased. Indicates what? Treatment?
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K = Koagulation time. Decreased = speed of clot formation and strengthening. Prolonged: give Kryo.
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TEG. Teardrop formation. Indicates what? Treatment?
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Early fibrinolysis. Give antifibrinolytic (eg TXA).
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Order of TEG values
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R, K, alpha angle, MA.
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toxic dose of bupivacaine?
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2.5 mg/kg or 3 m/kg with epi
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toxic dose of ropivacaine?
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3 mg/kg
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axillary nerve block targets which three nerves? What does it miss?
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median (medial forearm sensation), radial (dorsal hand sensation), ulnar (palmar hand). Misses musculocutaneous (lateral forearm
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lumbar plexus block spares what nerve?
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It gets the femoral (hip flexion, extension of the lower leg at the knee), lateral femoral cutaneous, and obturator (adduction), sciatic (L4-S3 - LPB gets L1-L4 and part of T12), so foot and ankle movements are preserved.
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Incidence of ptx with supraclav block?
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up to 6.1%
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Incidence of ptx with infraclav block?
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0.2-0.7%
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Pain Dermatomes and Pain regions for labor stage one?
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T10-L1. Paracervical, Hypogastric plexus
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Pain Dermatomes and Pain regions for labor stage two?
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S2-S4. Pudendal nerve.
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ST segment depression is an indicator of what sort of myocardial ischemia?
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subendocardial
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ST segment elevation is an indicator of what sort of myocardial ischemia?
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Transmural
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Treatments for autonomic dysreflexia during surgery?
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Stop the surgical stimulus is possible. Pharm therapy: avoid beta blockade. Start with vasodilators such as nitroglycerine and nitroprusside. Other potential options: iv ganglion blockers, hydralazine, alpha adrenergic receptor blockers, calcium channel blockers, magnesium.
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Side effects of Prostaglandin E1?
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apnea, hypotension, fever
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Rule of nines for BSA burn calculations
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9 percent: each arm, head. 18 percent: leg, torso front, torso back.
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Progression of EKG signs for hyperkalemia
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peaked T waves, then lengethed PR interval (6.5-7.5), THEN prolonged QRS, THEN bradycardia, sine wave, vtach, progressing to asystole
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What EKG features to hyperkalemia and hypermagnesemia have in common?
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Prolonged PR interval, widened QRS complex
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Calcium abnormalites and ST intervals: relationship?
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Inverse relationship: HypOcalcemia causes prolonged ST interval, hypERcauses shortened ST interval (interval between ventric depol and repol).
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Describe blood supply to the liver
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75 percent portal vein, 25 percent hepatic artery
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metformin mechanism?
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inhibits gluconeogenesis by liver
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What regions of the heart does the PDA (posterior descending artery) supply?
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Posterior one-third of interventricular septum. Inferior wall and posterior base of LV. Posterior wall of RV. 70 percent have a PDA off the RCA, sometimes it's off the CX. Also known as posterior interventricular arter (PIV).
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Which coag factor is reduced in chronic liver disease that is NOT reduced in DIC?
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VIII
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Formula for Strong Ion Difference. How do changes in SID correlate to changes in pH?
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Strong cations (Na, K, Ca, Mg) minus Strong anions (Cl, lactate). Increased SID correlates with increased pH. Decreased SID, decreased pH.
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Which evoked potential is minimally affected by volatile anesthetic?
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Auditory Evoked Potentials
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Electrocautery is responsible for what percentage of OR fires?
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90
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TEF: most likely associated anomoly?
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congenital heart (15 to 35 percent)
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prolactinoma: why on carbergoline or bromocriptine?
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dopamine agonists, negative feedback neurotransmitter for prolactin
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p02 umbilical artery and vein?
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20 and 30
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Normal urine Na?
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20
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Normal serum osm?
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285-295
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Winter's Formula for expected amount of respiratory compensation
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PCO2 = 1.5 * bicarb +8 plus or minus 2
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chemotherapeutic agents that cause cardiotoxicity
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doxirubicin
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chemotherapeutic agents that cause pulmonary toxicity
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bleomycin
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chemotherapeutic agents that cause nephrotoxicity
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cisplatin, carboplatin, tacrolimus, cyclosporine
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chemotherapeutic agents that cause peripheral neuropathy
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vincristine
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sodium nitroprusside toxicity triad?
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elevated mixed venous oxygen, SNP tachyphlaxis, and metabolic acidosis
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wide complex QRS is defined as greater than how many seconds?
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0.09
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effects of sodium bicarb on calcium and potassium
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hypOcalcemia (temporarily binds Ca2+), hypOkalemia (alkalosis drives potassium into cells)
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lead most sensitive for detection of MI?
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V (75 percent, 90 if you add V4 and V5, 80 if you add II which is tood for rhythm detection)
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hypoalbuminemia, like with burn patients: give less of this common drug
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midazolam. Hypoalb increases the free fraction of benzos, which are highly albumin bound. Fentanyl to a lesser extent.
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complete bilateral recurrent laryngeal nerve injury: effect?
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aphonia, aspiration risk. Cords in paramedian position (both abduction and adduction affected).
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refractory (to phenyl, ephed) hypOtn on induction caused by ACE-I: drug of choice?
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Norepi over vaso
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Which nerve runs alongside the brachial artery in the upper arm and AC fossa?
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MEDIAN!
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Minimum pressure differences for UE and LE tourniquets?
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50 above BP for upper, 100 above BP for lower
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acetazolamide: what does it do to sodium, bicarb, chloride, and potassium?
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Acetazolamide is a carbonic anhydrase inhibitor that will increase minute ventilation. it wastes sodium and bicarb in the proximal tubule, which leads to a hyperchloremic metabolic acidosis. Hypokalemia ensues thanks to sodium potassium exchange. It also wastes phosphate!
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which one crosses the placenta: atropine or glyco?
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Atropine (tertiary) - glyco is quaternary
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Tamponade CVP tracing
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exaggerated X-descent (atrial relaXation), attenuated y descent
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Constrictive pericarditis CVP tracing
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exaggerated x and y descent (change in compliance)
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Hydroxyethyl starch affects coagulation by which mechanism?
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Decreased Factor VII
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Normal urine specific gravity?
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1.000 to 1.030
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