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8 Cards in this Set
- Front
- Back
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The coca leaf
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regions of bolivia, ecuador, peru
shrub called the coca bush or coca tree grows there. Drug is from ancient use Incas - had important religious use |
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Pharmacokinetics of Stimulants
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cocaine, amphetamines, and other like stimulants are readily absorbed after oral administration
Administered intranasally |
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Cocaine vs. amphetamines
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cocaine is metabolized rapidly
most effects gone 20-80 min. after administration. cocaine detectible in urine 2-3 days after administration |
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acute effects at low doses
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cocaine & amphetamines = mood elevation, increased talkativeness & sociability
Increase in alertness & arousal |
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acute effects at high doses
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characteristic psychotic state emerges.
paranoid delusions are most common. also compulsive stereotyped behavior like rocking, hair pulling, chain smoking, or "fiddling with things" |
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Overdoses
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cocaine has had reports at as little as 20mg.
high dose of amphetamines = convulsions or seizures, resulting in respiratory collapse, heart attack, and stroke |
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effects of chronic use
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users develop a tolerance for the drug.
Acute tolerance develops for cocaine first, which means the effects from the 1st administration of the drug are not produced by a 2nd administration shortly afterward, unless high dose is used |
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Certain fact about children with ADHD and stimulant use
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they DO improve performance in children with ADHD
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