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29 Cards in this Set
- Front
- Back
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general rules for cellular maturation (giemsa)
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Size, Nucleus, N/C ratio, Nucleoli, cytoplasmic colour
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according to cellular maturation, the larger the cell is ...
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more immature, except for megacaryocytes
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according to cellular maturation .. the young cells nucleus look ..
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delicate, fine, open chromatin
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according to cellular maturation..the mature cells nucleus look ..
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condensation of chromatin, more coarse
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according to cellular maturation..the Nucleoli
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more likely in the immature cell
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according to cellular maturation .. the cytoplasmic colour of young cells are
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more blue or basophilic (more protein) ...exception plasma cells >> always blue
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plasma cells are always very blue or basophilic why?
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because of protein synthesis >> high RNA content
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RBCs count in men and women
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men = 4.5 -5.9 * 10^12/L
women = 4.1 -5.1*10^12/L |
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WBCs count
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4-11*10^9
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Differential count for WBCs
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segmented neutrophils 50-60%
lymphocytes 30-40% monocytes 6-12% bands 1-3% eosinophils 1-3% basophils 0-1% |
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platelets are stained by :
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Wright-giemsa stain
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RBCS morphology
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7 micron in diameter, disc shaped. appears round on a smear, rim of hemoglobin and a clean central area. central pallor, less than 1/2 the diameter
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segmented neutrophil morphology
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round cells. 10-14 micron in diameter, lobuled nucleus, 2 to 5 lobes connected with thin chromatin
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what is special about female neutrophil ?
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presence of drum stick
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what is found in neutrophil cytoplamsm ?
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primary granules (peroxidase, acid phosphatase)
secondary granules(collagenase, lactoferin, lysozyme) |
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what is the difference btwn neutrophil and band ?
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band is young segmented neutrophil and its nuclues is U-shaped
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what is the characterstic of eosinophil cytoplasm ?
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red-orange granules
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describe eosinophil
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slightly larger than neutrophils - only 2 lobes connected by thin chromatin
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describe the Basophil
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similar to neutrophils - deeply basophilic dark cytoplasmic granules which some times obscure the nucleus
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describe the lymphocyte
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small in size, 10 micron in diameter, small amount of cytoplasm
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describe the Monocyte
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the largest cell in blood,15-22 micron in diameter, kidney shaped nuclues, blue-gray cytoplasm
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classify WBCS according to size from the largest one to the smallest
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monocyte-
esoinophil- basophil = neutrophil lymphocyte |
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what are the precursors of platelet
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Megakaryoblast
Megakaryocyte |
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what is the difference btwn megakaryocyte and megakaryoblast morphologicly ?
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megakaryoblast -megakaryocyte
smaller larger round intercon. lobes dark blue bluish purple |
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pletelet come from ..
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cytoplasmic granules of megakarycyte
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what are the cell found in bone marrow
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lymphocyte-lymphoblast
monocyte - monoblast plasma cell osteoblast - osteoclast macrophage |
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what are the differences btwn plasma cell and osteoblast ?
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plasma oval shape
osteoblast olengated shape perinuclear golgi - central gologi |
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wht the difference btwn megakaryocyte and osteoclast?
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megakaryocyte is multilobed connected nucleus
osteoclast multiple not interconnected nucleus |
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RBCs appearance on thin and thick area
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thin area - no pallor
thick area - pilling of RBCs |
