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11 Cards in this Set
- Front
- Back
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IL-1
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Secreted by monocytes, macrophages, others
Stimulates T cell proliferation and IL-2 production |
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IL-2
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from macrophages, T cells and NK cells
Stimulates proliferation of T cells, B cells and NK cells; activates monocytes |
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IL-3
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from T cells
acts as growth factor for tissue mast cells and hematopoietic stem cells |
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IL-4
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From T cells
Promotes growth of B and T cells; enhances expression of HLA class II antigens |
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IL-5
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From T cells
Promotes maturation of B cells into plasma cells |
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IL-6
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From T cells, monocytes, and other cells
Promotes maturation of B and T cells and inhibits growth of fibroblasts |
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IFN-alpha
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From B cells and macrophages
Has antiviral activity |
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IFN-beta
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From fibroblasts
has antiviral activity |
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IFN-gamma
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T cells and NK cells
has antiviral activity; activates macrophages; enhances expression of HLA class II antigens |
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TNF-alpha (cachectin)
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From macrophages, T cels, and NK cells
Stimulate T cell proliferation and IL-2 production; cytotoxic to some tumor cells |
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TNF-beta
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from T cells
stimulates T cell proliferation and IL-2 production; cytotoxic to some tumor cells |
