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11 Cards in this Set

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IL-1
Secreted by monocytes, macrophages, others

Stimulates T cell proliferation and IL-2 production
IL-2
from macrophages, T cells and NK cells

Stimulates proliferation of T cells, B cells and NK cells; activates monocytes
IL-3
from T cells

acts as growth factor for tissue mast cells and hematopoietic stem cells
IL-4
From T cells

Promotes growth of B and T cells; enhances expression of HLA class II antigens
IL-5
From T cells

Promotes maturation of B cells into plasma cells
IL-6
From T cells, monocytes, and other cells

Promotes maturation of B and T cells and inhibits growth of fibroblasts
IFN-alpha
From B cells and macrophages

Has antiviral activity
IFN-beta
From fibroblasts

has antiviral activity
IFN-gamma
T cells and NK cells

has antiviral activity; activates macrophages; enhances expression of HLA class II antigens
TNF-alpha (cachectin)
From macrophages, T cels, and NK cells

Stimulate T cell proliferation and IL-2 production; cytotoxic to some tumor cells
TNF-beta
from T cells

stimulates T cell proliferation and IL-2 production; cytotoxic to some tumor cells