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16 Cards in this Set
- Front
- Back
- 3rd side (hint)
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GM-CSF
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T cells, macrophages
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stimulates growth and differentiation of cells of monocytic lineage
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IFN-α
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leukocytes and dendritic cells
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antiviral, increased MHC I expression
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IFN-β
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fibroblasts
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antiviral, increased MHC I expression
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IFN-γ
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T cells, NK cells
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Macrophage activation, increased expression of MHC molecules and antigen processing components, Ig class switching, suppresses TH2
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IL-1
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macrophages, epithelial cells
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Fever, T cell activation, macrophage activation
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IL-2
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T cells
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T cell proliferation
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IL-3
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mast cells
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Stimulates eosinophils, monocytes, dendritic cells and other cells of the myeloid lineage
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IL-4
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T cells, mast cells
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B-cell activation, IgE switch, induces differentiation into TH2 cells
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IL-5
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T cells, mast cells
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Eosinophil growth, differentiation
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IL-6
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T cells, macrophages, endothelial cells
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T and B cell growth and differentiation. Acute phase protein, fever
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IL-7
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Non-T cells
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Growth of pre-B and pre-T cells
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IL-10
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Monocytes, T cells
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suppression of macrophage functions, differentiation of B cells
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IL-12
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macrophages, dendritic cells
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activates NK cells, induces TH1 cells
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IL-13
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T cells, mast cells
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B cell growth and differentiation, inhibits macrophage inflammatory cytokine production and TH1 cells, induces allergy
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TNF-α
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macrophages, NK cells, T cells, mast cells
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promotes inflammation, endothelial activation
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CD40 ligand
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T cells, mast cells
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B cell activation, class switching
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