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11 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Chemokine |
Structurally homologous cytokines that stimulate leukocyte movement |
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ELR CXC chemokines |
Neutrophil migration, angiogenic |
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CX3CL1 |
T cell, NK cell, and monocyte recruitment |
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CCL19 |
T cell and dendritic cell migration into parafollicular zones of lymph nodes |
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XCL1 |
T cell and NK cell recruitment |
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CXCR4 |
CXCL12, B cell migration into lymph nodes, plasma cell migration into bone marrow. Whim's disease |
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Homologous desensitization |
GPCR selectively phosphorylates chemokine occupied receptors, leading to endocytic uptake |
Receptor decreases it's response to an agonist |
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Chemokines produced by |
Leukocytes |
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Chemokine receptors are members of |
GPCR |
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CCR7 |
T cell and dendritic cell migration into parafollicular zones of lymph nodes |
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CD49e |
Involved in cell to cell/matrix interactions. Adhesive interactions between lymphocytes and APCs |
Integrin |
