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5 Cards in this Set
- Front
- Back
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What percentage of CF patients carry the deltaF508 mutation? |
70% |
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What is the most common lethal AR disorder in Caucasians? |
CF |
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What are the clinical manifestations of CF? |
Chronic respiratory lung infections, inflammation, obstruction leading to lung disease Exocrine pancreatic insufficiency intestinal obstruction/meconium illeus CBAVD DM Progressive obstructive liver disease |
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What are the class I, II, and III mutation? |
absent CFTR more severe pheno with pancreatic insufficiency |
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What are Class IV and V mutations? |
retain partial CFTR, more mild pheno, pancreatic sufficiency |
