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19 Cards in this Set
- Front
- Back
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What are the three factors that increase membrane Fluidity?
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1.) shorter FA chains
2.) increased number of unsaturated FA chains 3.) decreased cholesterol content in the membrane |
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What are the three types of lipids in the plasma membrane, and which is most abundant?
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1.) Phospholipids (most abundant)
2.) Glycolipids 3.) Cholesterol |
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What are the two catagories of phospholipids?
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Glycerol based
Sphingocene based |
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What are the 5 important glycerol-based phospholipids, and which is found most abundantly?
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1.) Phosphatidylcholine (Lecithin)***
2.) Phosphatidylethanolamine 3.) Phospatidylserine 4.)Phosphatidylinositol 5.) Cardiolipin |
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Give an example of a 16C saturated FA
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Palmitic
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Give four examples of 18C FA's; one saturated and three unsaturated. Denote essential FA's.
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Saturated: Stearic
Unsaturated: Oleic (18:1) Linoleic (18:2) Linolinic (18:3) |
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Give one example of a 20C unsaturated FA
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Arachidonic (20:4)
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What is the structure of Phosphotidate?
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3C, two FA's attached to O groups, one phosphate group attached to last O group.
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What does hydrolysis of Lecitin yield?
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Lecitin=Phosphotitocholine=
one phosphate two fatty acids one choline one glycerol |
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What is the basic structure of sphingosine?
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Serine + FA
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What is the basic structure of ceramide?
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Sphingosine + FA
(Serine + FA) |
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What is the basic structure of sphingomyelin?
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Ceramide + phosphorylcholine
(Serine + FA + FA) and (phosphate + choline) |
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What is the major function of glycolipids?
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cell-to-cell recognition, form linkages to ECM, and absorption
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What are the two major diseases associated with glycolipids?
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Tay Sachs and Gaucher's
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What are the three types of glycolipids, and what are the major components for each?
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Cerebrosides: Ceramide + simple sugar
Sufatides: Cerebroside + sulfate Gangliosides: ceramide + oligosaccharide |
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Draw the structure for Cholesterol:
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Three 6-carbon rings
One 5 carbon ring One hydroxyl group Two methyl projections One beta-bond 1,5-methyl hexane from 5C ring |
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What is a glycoprotein?
Give an example |
Protein associated with an oligosaccharide.
Integrin: transmembranous bond to fibronectin, allowing association to ECM and cytoskeleton. |
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What are the two types of membranous proteins?
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Receptors and Transporters
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What four things must be present in order for signaling to occur?
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1.) Chemical signal
2.) Membrane-bound receptor 3.) Effector (c-AMP, Ca2+ channel) 4.) GTP-binding protein |
