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19 Cards in this Set

  • Front
  • Back
DDx for dyspnea on exertion:
HAAAM CO
Hypothyroid
Anemia
Angina
Anxiety and Hyperventilation
Metabolic Acidosis
Congestive Heart Failure
Obstructive Airway Disease
Obstructive Airway Disease
Orthopnea - dyspnea when _____
supine - as in CHF, asthma, COPD
Paroxysmal noctural dyspnea - waking at night short of breath as in what two conditions that start with acronym C
Chronic Heart Failure
COPD
Trepopnea - dyspnea when doing what. What condition?
laying on side
CHF
What is a syndrome of dyspnea on exertion, edema of the lungs or extremities and fluid retention resulting from cardiac dysfunction
Congestive Heart Failure
What are the three determinents of stroke volume?
Preload
Contractility
Afterload
Why is adrenergic stimulation controversial in heart failure?
It helps contractility, but it also increases afterload (vascular resistance) and may cuase arrhythmias
Neurohormone secreted from the cardiac ventricles in response to volume expansion and pressure overload.
B-type natriuretic peptide (BNP)
If someone has dyspnea and BNP levels come back high - what can you diagnose?
Chronic Heart Failure
NY Heart Association Functional Classification - what's the difference between Class I and Class IV
Class I - no limitation on physical activity
Class IV - symptoms at rest, can't carry on any physical activity without symptoms
Which test is the gold standard to distinguish cardiac heart failure
Cardiac echo - indicates Left Ventricular Failure and decreased ejection fraction
What two drug classes work on Preload?
Do they improve survival?
Diuretics
Vasodilators (venoselective)

NO - not by themselves
Which two drug classes work on increasing myocardial contractility?
Do they improve survival?
Digoxin
Dobutamine

Digoxin reduces morbidity when also on diuretics and ACE inhibitors
What three drug classes work on afterload treatment?
Do they improve survival?
Arterial vasodilators
ACE inhibitors
Angioreceptor II receptor blockers
YES! ACE inhibitors do big time... also ARBs
What are two Neurohumeral Treatments?
Do they improve survival?
Spironolactone - aldosterone antagonist
Carvedilol - selective beta blocker
Both - yes!
How is BNP used - what is the drug name?
What is the major side effect?
Nesiritide
Needs to be infused
Very expensive
used for stage IV heart failure

Hypotension
What drugs are contraindicated for diastolic dysfunction?
What is the best drug to use for diastolic dysfunction?
Preload drugs... Diuretics and vasodilators (pts don't tolerate lowered plasma volume or BP)

Beta blockers
Hepatomegaly can be a sign of what?
Right ventricular heart failure
What aspect of SV does Enalapril work on?
An afterload reducer - ACE inhibitor's direct effect is vasodilation of the arteries and veins