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22 Cards in this Set
- Front
- Back
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Describe how Class IB drugs affect sinus rate, PR interval, QRS duration, and QT duration at therapeutic and toxic levels
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Sinus Rate:
Ther: - Toxic: - PR interval Ther: - Toxic: - QRS duration: Ther: - Toxic: ^^^, (I_Na block) QT duration: Ther: - Toxic: - (no I_K block) |
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Describe how Class IC drugs affect sinus rate, PR interval, QRS duration, and QT duration at therapeutic and toxic levels
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Sinus Rate:
Ther: - Toxic: vvv PR interval Ther: - Toxic: ^^^ QRS duration: Ther: ^ Toxic: ^^^, (I_Na block) QT duration: Ther: - Toxic: - |
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Describe how verapamil drug affects sinus rate, PR interval, QRS duration, and QT duration at therapeutic and toxic levels
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Sinus Rate:
Ther: v Toxic: vvv (I_Ca block) PR interval Ther: ^ Toxic: ^^^ (I_Ca block) QRS duration: Ther: - Toxic: - (No I_Na block) QT duration: Ther: - Toxic: - (No I_K block) |
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Describe how digitalis drug affects sinus rate, PR interval, QRS duration, and QT duration at therapeutic and toxic levels
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Sinus Rate:
Ther: v Toxic: vvv (parasympathetic) PR interval Ther: ^ Toxic: ^^^ (parasympathetic) QRS duration: Ther: - Toxic: - (No I_Na block) QT duration: Ther: - Toxic: - (No I_K block) |
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What type of pacemaker is used for tachycardia caused by reentry?
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A pacemaker that delivers short bursts of rapid stimulation that will often abolish the tachycardia. When the pacemaker is turned off, the heart will once again be in sinus rhythm.
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Where is the pacemaker positioned for sinus bradycardia?
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R atrium
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Where is the pacemaker positioned for AV block?
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R ventricle
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What is ablation used to treat?
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-Atrial flutter
-AV nodal reentrant tachycardia -Not used for atrial fibrillation (may be associated with multiple reentrant circuits) or ventricular tachycardia (reentrant circuits are difficult to isolate) |
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Describe how Sotalol affects sinus rate, PR interval, QRS duration, and QT duration at therapeutic and toxic levels
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Sinus Rate:
Ther: v Toxic: vvv (beta block) PR interval Ther: ^ Toxic: ^^^ (beta block) QRS duration: Ther: - Toxic: -, no I_Na block QT duration Ther: ^ Toxic: ^^^ (I_K block) |
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Describe how Dofetilide affects sinus rate, PR interval, QRS duration, and QT duration at therapeutic and toxic levels
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Sinus Rate:
Ther: - Toxic: - (no beta block) PR interval Ther: - Toxic: - (no beta block) QRS duration: Ther: - Toxic: -, no I_Na block QT duration Ther: ^ Toxic: ^^^ (I_K block) |
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Describe how Amiodarone affects sinus rate, PR interval, QRS duration, and QT duration at therapeutic and toxic levels
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Sinus Rate:
Ther: v Toxic: vvv (symp or I_Ca block) PR interval Ther: ^ Toxic: ^^^ (symp of I_Ca block) QRS duration: Ther: ^ Toxic: ^ (I_Na block) QT duration Ther: ^ Toxic: ^^^ (I_K block) |
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Describe how Ibutelide affects sinus rate, PR interval, QRS duration, and QT duration at therapeutic and toxic levels
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Sinus Rate:
Ther: - Toxic: - (no beta block) PR interval Ther: - Toxic: - (no beta block) QRS duration: Ther: - Toxic: -, no I_Na block QT duration Ther: ^ Toxic: ^^^ (I_K block) |
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Describe how propanolol affects sinus rate, PR interval, QRS duration, and QT duration at therapeutic and toxic levels
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Sinus Rate:
Ther: v Toxic: vvv (beta block) PR interval Ther: ^ Toxic: ^^^ (beta block) QRS duration: Ther: - Toxic: -, no I_Na block QT duration Ther: - Toxic: - (no I_K block) |
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Describe how Disopyramide affects sinus rate, PR interval, QRS duration, and QT duration at therapeutic and toxic levels
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Sinus Rate:
Ther: ^ (vagolytic) Toxic: vvv PR interval Ther: v (vagolytic) Toxic: ^^^ QRS duration: Ther: ^ Toxic: ^^^, (I_Na block) QT duration Ther: ^ Toxic: ^^^ (I_K block) |
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What is chronic oral therapy for the treatment of atrial fibrillation/flutter by rhythm control?
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-Class III (sotalol, amiodarone, dofetilide)
-Class IA (disopyramide) (not if there is concomitant ventricular disease) -Class IC (flecainide, propafenone) (not if there is concomitant ventricular disease) -Class II (propranolol, etc.) (if sympathetics are implicated) |
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What is acute IV therepy for the treatment of atrial fibrillation/flutter by rhythm control?
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Ibutilide (atrial fibrillation)
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What is ablation used for?
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-For atrial fibrillation arising in pulmonary veins
-For typical reentrant atrial flutter |
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What is used for treatment of atrial fibrillation by rate control?
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-Class IV (verapamil, diltiazem)
-Class II (beta receptor blockers) -Digitalis |
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What is used for the treatment of paroxysmal Supraventricular Tachycardia caused by AV nodal reentry?
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-Class IV (IV or oral verapamil, diltiazem)
-Class II (IV or oral beta blockers) -Adenosine (IV for rapid termination) -Ablation of reentrant circuit |
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What is acute IV thereapy (in ICU or coronary care unit) for treatment of ventricular tachycardia/ventricular fibrillation?
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-Class III; amiodarone (also out of hospital resuscitation after rhythm has been reestablished with defibrillation shock to prevent fibrillation)
-Class IB: lidocaine -Class IA; Procainamide **Drugs will not convert ventricular fibrillation back to sinus rhythm ***Drugs MAY decrease mortality in the acute setting |
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What is the chronic oral therapy for treatment of ventricular tachycardia/ventricular fibrillation?
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-Class III sotalol, amiodarone (relieves symptoms by decreasing occurrence of VT, decreases number of ICD shocks, no data show that they increase survival when used as monotherapy)
-Class II beta blockers (decrease mortality) **Drugs will not convert ventricular fibrillation back to sinus rhythm |
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Describe implantable cardiac defibrillation (ICD)
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-Decreases mortality when used appropriately
-Converts ventricular fibrillation to sinus rhythm |
