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46 Cards in this Set
- Front
- Back
GH and prolactin are secreted by the _____ pituitary and are (acidophilic/basophilic)
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anterior; acidophilic
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ACTH, FSH, LH and TSH are secreted by the _____ pituitary and are (acidophilic/basophilic)
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basophilic
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ACTH is a ________troph, TSH is a ______troph, and FSH and LH are ____trophs
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act corticotroph, tsh thyrotroph, fsh and lh gonadotroph
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ADH and oxytosin are released from and produced in the
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posterior pituitary; hypothalamus
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hyperpituitarism are usually caused by an ______ of the ______ lobe of the pituitary
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adenoma; anterior lobe
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adenomas of the pituitary produce an excess of multiple hormones secreted by that part of the pituitary
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false (amost true), usully produces excess of one type of hormone
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pituitary adenomas are present in ___% of autopsied people
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25%
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GH adenoma before poohberty causes ______; after pooberty ______
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before gigantism; after acromegaly
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cushings disease is an increased production of _____
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glucocorticoids (as happens in hyperproduction of ACTH
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empty sella syndrome is a (hyper/hypo)function of the _______
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hypo pituitiary
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Anterior pitutitary hypofuncion due to postpartum ischemic necrosis
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Sheehan's Syndrome
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most frequesnt cause of hypopituitarism
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non-secretory pituitary adenoma
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abrupt enlargement of a pituitary adenoma due to acuet hemorrhage within the tumor is calld a
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pituitary apoplexy
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ADH oversecretion is most often due to
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ADH producing tumor sucha as a smoall oat cel carcinoma of the lung
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Syndrome that results in renal retention of water with an inablilty to diulte urine
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Syndrome of inappropriate ADH (SIADH)
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ADH undersecretion causes
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you to pee a lot
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Graves disease is (hyper/hypo)secretion of what hormone and is most common in which gender
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hyperthyroidism, female 7:1
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warm skin, sweating, heat intolerance, hyper0motility of GI tract, increased apetite, osteoporisis, iritabitly, fine oily hair
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hyperthyroidism
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what should you do in a thyroid storm (sudden attack of hyperthyroidism)
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stop dental proceedure, give O2, take vitals, give nitroglycerin and call 911
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hashimotos is
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cells are ineffiecient in converting iodine to thyroid hormone so gland compensates by enlarging. Thyroid tissue is replaced by lymphocytescauses primary hypothyroidism
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wide set eyes, coarse facial features, protruding tongue and umbilicus and severe mental retardation (think eric)
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cretinism
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kind of an adult version of cretinsm (lethartgy, cold intolerance, broad face, tongue enlargement, coarse dry hair)
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myxedema
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most common cause of primary (endogenous) hyperthyroidism
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graves disease
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pretibial myxedema (thickening of the skin over legs and dorsal foot), bulging eyes (exopthamos), and thyrotoxicosis
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graves disease
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HLA-DRS is to _____ as HLA DR3 is to _____
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non-specific lyphoid thyroiditis ; graves disease
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most common cause of hypthyroidism in usa
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hashimotos thyroditis
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autoimmune disease in which there is an increased risk of b-cell lymphoma and auitoantibodies anti-thyroglobulin, anti-thyroid, anti-TSH receptor, anti-iodine receptor are present
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hashimotos thyroditis
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orphan annie nuclei
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papillary carcinoma
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prognoisi for papillary carcinoma of the thyroid is ______, anaplastic (undifferentiated) carcinoma of thyroid is _____-
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good bad
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medulary carcinoma can be associated with
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MEN syndrome Iia and IIb (III)
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"cold" nodule on a scan
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follicular carcinoma of the thyroid
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elevated PTH causes
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stones (kidney), moans, (pain_, bones (excessive bone resorption), groans (gi problems, like constipation)
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Stones groans moans and bones refers to what disorder
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primary hyperparathyroidism
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most common cause of secondary hyperparathyroidism
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renal failure
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chvostek's sign
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unilateral spasm in face by tapping on facial nerve
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adrennal cortex secretes __________, _________, and ________
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glucocorticoids (cortisol), Mineralcorticoids (aldosterone), androgens
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cushings disease is an increased production of _____, that cuases adrenal (atrophy/hypertrophy)
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glucocorticoids, (either, depending on whether it is caused by exogenous corticosteroids being administered (atrophy), or ectopic tumor producing ACTH (hyperplasia)
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cushing's syndrome can be caused by adrenal tumor producing cortisol. This causes nodular hyperplasia.
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true; true
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Conn's syndrome is ________ _________ and is due to _______ serum renin
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primary hyperaldosteronism, decreased
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secondary aldosteronism is due to renal ischemia, ediema or nephroticsyndrome and exhibits _______ serum renin
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which two diseases are asssociated with adrenal hypofuncion
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addisions' and waterhous-friderichsen disease
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the rule of tens applies to ___________ which is overproduction of epinephrine, norepinephrine and VMA that causes hypertension
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pheochromocytoma
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Wermer syndrome is commonly called _____ and linked to chromosome ___
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MEN I, 11
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More than one of the following are involved: pituitary, parathyroid, pancreatic islets, adrenal cortex
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MEN I (wermer syndrome)
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Sipple syndrome is calso called ____, and linked to chromosome ___
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MEN II, 10
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MEN Iib (MEN III) is simliar to MEN ___, except it involves skin, and tongue
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IIa
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