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14 Cards in this Set
- Front
- Back
Superficial Squamous Cells Features When are they seen? |
outermost layer of the non-keratinizing epithelium. eosinophillic polygonal shaped cell centrally placed pyknotic nucleus Superficial squamous cells are seen in abundance during the late proliferative and ovulatory phases of the menstrual cycle. At these points, estrogen is at its peak. |
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Intermediate Squamous Cells |
The intermediate cell’s cytoplasm is thin, transparent, and typically stains basophilic. The nucleus is vesicular with fine evenly dispersed granular chromatin. |
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Squamous Metaplastic Cells Why do abnormalities occur here? |
round to polygonal in shape with dense biphasic staining cytoplasm and round centrally located nuclei. arise from the basal layer of glandular epithelium as a protective response to stimuli, creating the transformation zone. metabolically active cells are often the site where abnormalities occur. |
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Normalectocervix |
non-keratinisedstratified squamous. Basal layer, parabasal layer, intermediate cell layer,exfoliating cells |
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Endocervix |
one layer of simple columnar and tall mucin secretingepithelia |
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Stainingresults
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very transparent cells, blue-black nuclei. Superficial cellsare orange to pink, and parabasal are green to blue. Metaplastic cells oftenstain both green and pink at once. |
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Colour |
More pink than blue – younger.
More blue – ageing, atrophyas cells cannot divide |
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H&E staining |
Haematoxylin – basic dye, binds acidic structures, stainsblue/purple. Eosin – acidic dye, stains pink |
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Uterus endometrium cell type |
Mucosa of uterus Consists of simple columnar epithelium and connective tissue (stroma) |
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Uterus myometrium cell type
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Outer wall Interconnecting bundles of smooth muscle Prominent blood vessels Hormone sensitive. Undergoes hyperplasia and hypertrophy. |
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Outer layer of uterus |
Serosa |
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Change in myometrial cells during menopause |
Hormonal cessation Atrophy and uterus shrinks |
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Cell type in ectocervix |
Hard, squamous cells |
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Cell type in endocervix |
Soft, columnar glandular cells |