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14 Cards in this Set

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Superficial Squamous Cells


Features




When are they seen?

outermost layer of the non-keratinizing epithelium.


eosinophillic polygonal shaped cell




centrally placed pyknotic nucleus




Superficial squamous cells are seen in abundance during the late proliferative and ovulatory phases of the menstrual cycle.


At these points, estrogen is at its peak.

Intermediate Squamous Cells

The intermediate cell’s cytoplasm is thin, transparent, and typically stains basophilic.




The nucleus is vesicular with fine evenly dispersed granular chromatin.

Squamous Metaplastic Cells




Why do abnormalities occur here?

round to polygonal in shape with dense biphasic staining cytoplasm and round centrally located nuclei.




arise from the basal layer of glandular epithelium as a protective response to stimuli, creating the transformation zone.




metabolically active cells are often the site where abnormalities occur.

Normalectocervix

non-keratinisedstratified squamous. Basal layer, parabasal layer, intermediate cell layer,exfoliating cells

Endocervix

one layer of simple columnar and tall mucin secretingepithelia

Stainingresults

very transparent cells, blue-black nuclei. Superficial cellsare orange to pink, and parabasal are green to blue. Metaplastic cells oftenstain both green and pink at once.

Colour

More pink than blue – younger.
More blue – ageing, atrophyas cells cannot divide

H&E staining

Haematoxylin – basic dye, binds acidic structures, stainsblue/purple.


Eosin – acidic dye, stains pink

Uterus endometrium cell type

Mucosa of uterus




Consists of simple columnar epithelium and connective tissue (stroma)

Uterus myometrium cell type

Outer wall


Interconnecting bundles of smooth muscle


Prominent blood vessels


Hormone sensitive. Undergoes hyperplasia and hypertrophy.

Outer layer of uterus

Serosa

Change in myometrial cells during menopause

Hormonal cessation


Atrophy and uterus shrinks

Cell type in ectocervix

Hard, squamous cells

Cell type in endocervix

Soft, columnar glandular cells