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56 Cards in this Set
- Front
- Back
what is the term used to describe the large vessels of the body? The small vessels?
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macrovasculature; microvasculature
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is the velocity of flow faster or slower at the capillaries and post-capillary venules?
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slower
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where in the circulatory system is the cross-sectional area the greatest?
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capillaries
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are the lymphatics part of the macro- or microvasulature?
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microvasculature
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what are the 3 layers outward of the blood vessel lumen?
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tunica intima, tunica media, tunica adventitia
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which layer of the blood vessel is in touch with the lumen?
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tunica intima
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what is the composition of the tunica intima?
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simple squamous epithelium (endothelium)
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what defines the outer limit of the tunica intima?
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internal elastic lamina
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what is the name for the layer of the vessels which lies between the internal and external elastic lamina?
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tunica media
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what is the composition of the tunica media?
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circularly arranged smooth muscle cells and fibroelastic connective tissue
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what is the name for the outermost layer of the blood vessels?
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tunica adventitia
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what is the composition of the tunica adventitia?
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mostly connective tissue and some smooth muscles in larger vessels
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which represent the blood and nerve supply to the vessels themselves? In which layer of the vessel do these lie?
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vaso vasorum and nervi vascularis; tunica adventitia
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which vessels have better developed layers, arteries or veins?
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arteries
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what is the dominant layer of the arteries? The veins?
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tunica media; tunica adventitia
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what are the name for the arteries closest to the heart? Why are they called this?
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elastic arteries; they have a significant component of elastic fibers in their media interspersed with the smooth muscle.
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what is the role of the elastic fibers in the elastic arteries?
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to allow the vessels to expand during systole and contract during diastole
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what is the name for the arteries downstream of the elastic arteries?
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muscular arteries
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what characterizes the muscular arteries? How many layers of smooth muscle exist?
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layers of circularly arranged smooth muscle cells, often with a prominent internal elastic lamina; 4-40 layers
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what is the role of the muscular arteries?
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they regulate blood flow to the organs
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what is the first member of the microcirculation which follows downstream of the muscular arteries?
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arterioles
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how many layer of smooth muscle are present in arterioles?
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1-3 layers
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which arterial segment is the main component of the TPR?
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arterioles
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what is the name for the arteries downstream of arterioles?
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metarterioles
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which types of arteries can feed the capillary bed?
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arterioles and metarterioles
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what are the names of connections between arteries and veins that bypass capillaries? Which types of arteries feed these connections? What controls this process?
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arteriovenous anastomoses; arterioles and metarterioles; precapillary sphincter mechanisms
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what is the average diameter of a capillary?
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9-12 microns
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what is the composition of the capillaries?
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attenuated endothelial cells
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what is the name for the cells which are located along the external surface of the endothelium of capillaries in a sporadic fashion? What is their function?
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pericytes; contractile and regenerative
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what are the 3 types of capillaries that have been identified?
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continuous, fenestrated, and discontinuous
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which of the 3 types of capillaries is the most common? How is exchange achieved across their walls?
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continuous; diffusion and pinocytosis
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which is the 3 types of capillaries have small pores in their walls?
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fenestrated
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by which structure are pores in fenestrated capillaries normally closed?
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pore diaphragm
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in which tissues are fenestrated capillaries normally found?
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kidney, small intestine, endocrine gland
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which type of capillaries have the largest pores? Which particles can pass through these pores?
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discontinuous capillaries; macromolecules and plasma proteins
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what characterizes the basement membrane of discontinuous capillaries?
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it is normally reduced or absent
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discontinuous capillaries are normally found in which tissues?
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liver, spleen, bone marrow
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into which vessels do capillaries drain?
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post-capillary venules
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what is thought to be the location where the majority of the blood-tissue gaseous and nutrient exchange takes place?
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post-capillary venules
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in which type of blood vessel do most of the white blood cells leave the circulation to enter the tissues
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post-capillary venules
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are the endothelial cells quiescent or metabolically active
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metabolically active
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what are 4 roles of the endothelial cells in blood vessels?
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synthesis and maintenance of the basement membrane, fine-tuning of blood coagulation mechanism, and local control of blood vessel constriction/dilation and vessel wall permeability
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in which process do the endothelial cells play a significant role?
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inflammatory process
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the larger veins have what composition?
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considerable elastic fibers and some smooth muscle arranged longitudinally
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which type of valves exist in the veins which permit unidirectional movement of blood to the heart?
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bicuspid
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what are the 3 layers of the heart?
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endocardium, myocardium, epicardium
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do lymphatics possess valves? What chacterizes their basement membrane?
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yes; incomplete
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what kind of collagen is found in the connective tissue of the tunica adventitia?
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type I
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how many layers of smooth muscle are most often present in metarterioles?
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1 layer
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which capillaries are most permeable to molecular transport?
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discontinuous
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in fenestrated capillaries, are pores within endothelial cells or between these cells?
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within
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the tone of smooth muscle cells encircling which vessels detemines how much blood enters capillaries?
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metarterioles
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which vessel looks like a large capillary under the microscope?
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post-capillary venules
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what function of the veins does the longitudinal smooth muscle allow?
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blood storage
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what kind of cells are Purkinje fibers?
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modified cardiac muscle cells
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are lymphatics strong or weak vessels?
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very weak
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