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24 Cards in this Set

  • Front
  • Back
How to see gross anatomy of a bone
radiographs are best.
Certain areas of the bone...
predispose to certain kinds of tumors
if tumor is slow growing....
normal bone has time to respond physiologically and will increase volume around the lesion so it appears white on plain xray.
if tumor is fast...
permeated pattern on xray because normal bone can't respond fast enough.
Malignancies like leukemia...
may not show any change on xray. but malignancies can present very variably.
acute inflammation (osteomyelitis)...
can resemble malignancy but clinical picture will suggest infection and not malignancy
If lesion mineralizes...
it came from cartilage or bone.

and cartilage lesions are only where there normally is cartilage (i.e. won't see it in certain parts of the face that have intramembranous ossification)
Osteosarcoma makes...
MALIGNANCY MINERALIZED BONE (doesn't necc go along with stress lines - the bone is oriented in a lacy way)
Cartilage lesions
often show rings and arcs bc that is how cartilage grows and then it is calcified around edges (endochondral ossification)
ground glass/stippled...
suggests fibrous dysplasia
Ivory/solid pattern of calicifcaiton
suggests malignant tumor causing more density of minrealized bone in the medulla.
2 kinds of periosteal reactions
codman's angle - looks like the periosteum has been lifted off. due to a lesion that grows btwn mineralizing periosteum and preexisting cortex. very typical of some malignancies or infections.

spiculated - bone growing perpendicular to long axis bc tumor is growing so fast the normal bone thinks that is the direction of force. very fast growth here.
slow growing-
benign

geographic margins (clear where the lesion is) and solid periosteal rxn
intermediate growing -
benign or malig

ill-defined or moth-eaten internal margins.

shells is the periosteal reaction.
fast growing -
malig

permeative internal margins and lamellar periosteal reactions
fastest growing -
malig

invisible internal margins and spiculated/invisible periosteal rxn.
first pge of notes
imp to know i think - table 1
issue with trauma and bone lesions
that is just what the pt remembers. often times, there is something (e.g. malignancy) that predisposed their trauma to actually result in a fracture
enchondroma
lytic lesion. geographical margin.
osteosarcoma
whole length will be abnormal. not geographic.

doesn't follow wolf's law.

quick death.
staphylococcus osteomyelitis
entire humerus in this case.
sign of dead bone
can't see osteocytes.
coccidioidomycosis osteomyelitis
granulomatous.

permeative destruction
metastatic carcinoma of bone
can induce bone formation via cytokine response