• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

Card Range To Study

through

image

Play button

image

Play button

image

Progress

1/160

Click to flip

Use LEFT and RIGHT arrow keys to navigate between flashcards;

Use UP and DOWN arrow keys to flip the card;

H to show hint;

A reads text to speech;

160 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)
Headache

-Throbbing pain
-lasts 2-3 hours
-sees flashes of light
-unilateral
-weakness & numbness
-family history of migraines
Migraine*

Tension Headache
Cluster headache
Psuedotumor Cerebri
trigeminal neuralgia
Partial Seizure
Intracranial Neoplasm
CBC
ESR
CT-Head
MRI-Brain
LP
Headache

- ipsilateral rhinorrhea
-eye tearing & redness
- last 45 mins
Cluster Headache*

Migraine
Tension headache
Sinusitis
trigeminal neuralgia
Partial Seizure
Intracranial Neoplasm
CBC
ESR
CT-Head
MRI-Brain
LP
Headache

-severe, intermittent right temporal headache
- blurred vision in one eye
- pain in jaw when chewing
Temporal arteritis*

Migraine
Cluster headache
Tension headache
Meningitis
Carotid Dissection
Pseudotumor Cerebri
Trigeminal Neuralgia
Intracranial Neoplasm
CBC
ESR
Temporal Artery Biopsy
Doppler U/S Carotid
MRI - brain
Frontal Headache

-fever
-nasal discharge
-pain with palpation of frontal & maxillary sinuses
-Hx of sinusiits
Sinusitis*

Migraine
Tension headache
Meningitis
Depression
Caffeine Withdrawal
Hypertension
Cluster headache
Pseudotumor Cerebri
Intracranial Neoplasm
CBC
Electrolytes
ESR
CT- head
LP
Headache

-sudden, severe
-vomiting
-confusion
-left hemiplegia
-nuchal rigidity
Subarachnoid Hemorrhage*

Migraine
Meningitis/Encephalitis
Intracranial Hemorrhage
Vertebral Artery Dissection
Intracranial Venous Thrombus
Acute Hypertension
Intracranial Neoplasm
CT - without contrast - head
LP
CBC
PT/PTT
MRI/MRA - brain
Headache

-high fever
-severe headache
-confusion
- photophobia
- Nuchal rigidity
Positive Kernig
Positive Brudzinski
Meningitis *

Migraine
Subarachoid Hemorrhage
Sinusitis/Encephalitis
Intracranial or Epidrual Abscess
CBC
CT - head
MRI- brain
LP - CSF analysis - cell count, protein, glucose, Gram stain, PCR for antigens
18 yo obese F presents with a pulsatile
headache, vomiting, and blurred vision
for the past 2–3 weeks. She is taking
OCPs.
Pseudotumor cerebri*

Tension headache
Migraine
Cluster headache
Meningitis
Intracranial venous thrombosis
Intracranial neoplasm
Urine hCG
CBC
CT—head
LP—opening pressure and CSF analysis
57 yo M c/o daily pain in the right cheek
over the past month. The pain is electric
and stabbing in character and occurs
while he is shaving. Each episode lasts
2–4 minutes.
Trigeminal neuralgia*

Tension headache
Migraine
Cluster headache
TMJ dysfunction
Intracranial neoplasm
CBC
ESR
MRI—brain
85 y/o M
Confusion
-Progressive confusion over years
-Forgetfulness
-clumsiness

Hx: HTN, DM, 2 strokes with hemiparesis
Mental status declined with each stroke
Vascular (“multi-infarct”)
dementia
Alzheimer’s disease
Normal pressure hydrocephalus
Chronic subdural hematoma
Intracranial tumor
Depression
B12 defi ciency
Neurosyphilis
Hypothyroidism
CBC
VDRL/RPR
Serum B12
TSH
MRI—brain
CT—head
LP—CSF analysis (rare)
84 y/o F

Forgetfulness
-forgets to do daily activities
-difficulty performing some daily tasks
Problem progressed over years
Alzheimer’s disease*

Vascular dementia
Depression
Hypothyroidism
Chronic subdural hematoma
Normal pressure hydrocephalus
Intracranial neoplasm
B12 defi ciency
Neurosyphilis
CBC
VDRL/RPR
Serum B12
TSH
MRI—brain (preferred)
CT—head
LP—CSF analysis (rare)
72 y/o M
- Memory Loss
- Gait disturbance
- Urinary Incontinence
Normal pressure hydrocephalus*
- wet, wacky, wobbly

Alzheimer’s disease
Vascular dementia
Chronic subdural hematoma
Intracranial neoplasm
Depression
B12 defi ciency
Neurosyphilis
Hypothyroidism
CT—head
LP—opening pressure and CSF
analysis
Serum B12
VDRL/RPR
TSH
55 y/o M
Rapidly Progressive change in mental status
- inability to concentrate
- memory impairment for 2 months
- myoclonus
- ataxia
Creutzfeldt-Jakob disease*

Vascular dementia
Lewy body dementia
Wernicke’s encephalopathy
Normal pressure hydrocephalus
Chronic subdural hematoma
Intracranial neoplasm
Depression
Delirium
B12 defi ciency
Neurosyphilis
CBC, electrolytes, calcium
Serum B12
VDRL/RPR
MRI—brain (preferred)
CT—head
EEG
LP—CSF analysis
Brain biopsy
70 y/o Diabetic Male

Confusion
Dizziness
Palpitations
Diaphoresis
Weakness
Hypoglycemia*

Transient ischemic attack
Arrhythmia
Delirium
Angina
Glucose
CBC, electrolytes
Echocardiography
ECG
MRI—brain
Doppler U/S—carotid
55 y/o F
Gradual Altered mental status
- Headache
Hx: 2 weeks ago, tripped and hit head
Subdural hematoma*

SIADH (causing hyponatremia)
Creutzfeldt-Jakob disease
Intracranial neoplasm
Electrolytes
CT—head
MRI—brain
LP
68 y/o M
2 month hx of:
crying spells, excessive sleep, poor hygiene, 7kg weight loss, after wife's death

- cannot enjoy time with grandkids
- thinks he sees his wife at supermarket or in kitchen
Normal bereavement*

Adjustment disorder with
depressed mood
Major depressive disorder with
psychotic features
Schizoaffective disorder
Depressive disorder not
otherwise specifi ed (NOS)
Physical exam
Mental status exam
TSH
CBC
Urine toxicology
42 y/o F
4 week history of:
excessive fatigue, insomnia, anhedonia
- constantly thinks about death
- 5 similar episodes in the past - first episode in 20s
- 2 suicide attempts
-increased alcohol use in last month
Major depressive disorder*

Substance-induced mood
disorder
Dysthymic disorder
Physical exam
Mental status exam
Blood alcohol level
TSH
CBC
Urine toxicology
26 y/o F

- 3 kg weight loss in last month
- early morning awakening
- excessive guilt
- psychomotor retardation
- no trigger for depressive episodes

- several weeks of increased energy, sexual promiscuity, irresponsible spending, racing thoughts
Bipolar I disorder*

Bipolar II disorder
Cyclothymic disorder
Major depressive disorder
Schizoaffective disorder
Physical exam
Mental status exam
Urine toxicology
19 y/o M
receiving msgs from television set
- not many friends in high school
- suspects roommate is bugging phone
- stopped going to class because believes professors are saying horrible things about him & nobody noticed
- hearing voices from TV telling him to guard against the evil empire
Schizophrenia*

Schizoid or schizotypal personality
Schizophreniform disorder
Substance-induced psychosis
Depression with psychotic features
Psychotic disorder d/t medical condition
Mental status exam
Urine toxicology
TSH
CBC
Electrolytes
28 y/o F
Bugs crawling on her bed
- Hearing loud voices when she's alone in her room
- never experienced this before
- recently ingested unknown substance
Substance-induced psychosis*

Brief psychotic disorder
Schizophreniform disorder
Schizophrenia
Psychotic disorder due to a
general medical condition
Urine toxicology
Mental status exam
TSH
CBC
Electrolytes, BUN/Cr, AST/ALT
48 y/o F
1 week hx of auditory hallucinations:
stating "I am worthless & "I should kill myself"

- 2 week history of weight loss
- decreased motivation
- feelings of guilt
Schizoaffective disorder
Mood disorder with psychotic
features
Schizophrenia
Schizophreniform disorder
Psychotic disorder due to a
general medical condition
Mental status exam
Beck Depression Inventory
TSH
CBC
Electrolytes
35 yo F presents with intermittent
episodes of vertigo, tinnitus, nausea, and
hearing loss over the past week.
Ménière’s disease*

Vestibular neuronitis
Labyrinthitis
Benign positional vertigo
Acoustic neuroma
CBC
VDRL/RPR (syphilis is a cause
of Ménière’s disease)
MRI—brain
55 yo F c/o dizziness for the past day.
- feels faint
- severe diarrhea for 2 days
- takes furosemide for her hypertension.
Orthostatic hypotension due
to dehydration (diarrhea,
diuretic use)*

Vestibular neuronitis
Labyrinthitis
Benign positional vertigo
Vertebrobasilar insuffi ciency
Orthostatic vital signs
CBC
Electrolytes
Stool exam (occult blood, fecal
leukocytes)
65 yo M
Postural dizziness & unsteadiness
- has hypertension
- started on hydrochlorothiazide 2 days ago
Drug-induced orthostatic
hypotension*

Vestibular neuronitis
Labyrinthitis
Benign positional vertigo
Brain stem or cerebellar tumor
Acute renal failure
Orthostatic vital signs
CBC
Electrolytes
BUN/Cr
MRI—brain
44 yo F c/o dizziness on moving her
head to the left.
- feels that the room spinning around her head.
- Tilt test results in nystagmus & nausea .
Benign positional vertigo*

Vestibular neuronitis
Labyrinthitis
Ménière’s disease
MRI—brain
Audiogram
55 yo F c/o
Dizziness - started today
- nausea & vomiting for 1 day
- URI - 2 days ago
- no hearing loss
Vestibular neuronitis*

Labyrinthitis
Ménière’s disease
Benign positional vertigo
Vertigo associated with cervical
spine disease/injury
Vertebrobasilar insuffi ciency
CBC
Electrolytes
Electronystagmography
MRI/MRA—brain
55 yo F c/o
dizziness - started this morning and of “not hearing well.”
- Nausea & vomiting 1 day
- URI 2 days ago
Labyrinthitis*

Vestibular neuronitis
Ménière’s disease
Acoustic neuroma
Vertebrobasilar insuffi ciency
Audiogram
Electronystagmography
MRI/MRA—brain
26 y/o M
Falling & LOC
- rhythmic movements of the limbs
- bit his tongue,
- voided bladder & bowels
- subsequently confused (as witnessed by his colleagues).
Seizure, grand mal (complex tonic-clonic seizure)*

Convulsive syncope
Substance abuse/overdose
Malingering
Hypoglycemia
CBC, electrolytes, glucose
Urine toxicology
EEG
MRI—brain
CT—head
LP—CSF analysis
ECG
55 yo M c/o falling after feeling dizzy
and unsteady.
- transient LOC
- Hx of HTN
- on multiple HTN drugs
Drug-induced orthostatic hypotension (causingsyncope)*

Cardiac arrhythmia
Syncope (vasovagal)
Stroke
MI
Pulmonary embolism
Orthostatic vital signs
CBC
Electrolytes
CT—head
ECG
V/Q scan
CT—chest with IV contrast
65 yo M
Falling and LOC for a few seconds.
- no warning prior to passing out
- had palpitations
- PMH: Coronary artery bypass grafting
(CABG)
Cardiac arrhythmia (causing syncope)*

Severe aortic stenosis
Syncope (other causes)
Seizure
Pulmonary embolism
ECG
Holter monitoring
CBC, electrolytes
Glucose
Echocardiography
CT—head
68 yo M
20 min episode of:
- slurred speech
- right facial
- drooping and numbness
- right hand weakness.

Sx resolved by time reached ER
Hx: HTN, DM, Heaving smoking
Transient ischemic attack (TIA)*

Hypoglycemia
Seizure
Stroke
Facial nerve palsy
CBC
Glucose
Electrolytes
ECG
CT—head
MRI—brain
Doppler U/S—carotid
Echocardiography
EEG
68 yo M
- slurred speech,
- right facial drooping and numbness,
- right hand weakness.

Babinski’s sign is present on the right. Hx: HTN, DM, Heaving smoking
Stroke*

TIA
Seizure
Intracranial neoplasm
Subdural or epidural hematoma
CBC, electrolytes
PT/PTT
CT—head
MRI—brain (preferred)
Doppler U/S—carotid
Echocardiography
33 yo F
- Ascending loss of strength in her lower legs over the past two weeks.
- had a recent URI.
Guillain-Barré syndrome*

Multiple sclerosis
Polymyositis
Myasthenia gravis
Peripheral neuropathy
Tumor in the vertebral canal
CBC, electrolytes
CPK
LP—CSF analysis
MRI—spine
EMG/nerve conduction study
Tensilon test
Serum B12
30 yo F
1 day hx of:
- weakness
- loss of sensation,
- tingling in her left leg

- right eye pain, decreased vision, & double vision.
- feeling “electric shocks” down her spine upon flexing her head.
Multiple sclerosis*

Stroke
Conversion disorder
Malingering
CNS tumor
Neurosyphilis
Syringomyelia
CNS vasculitis
CBC, ESR
VDRL/RPR
MRI—brain
LP—CSF analysis
Retinal evoked potentials
55 yo M
2 month hx of:
- tingling and numbness in the hands and feet (glove and-stocking distribution)
- decreased soft touch, vibratory,
and position sense in the feet.

Hx: DM, HTN, alcoholism
Diabetic peripheral neuropathy*

Alcoholic peripheral neuropathy
B12 defi ciency
Hypocalcemia
Hyperventilation
Paraproteinemia/myeloma
HbA1c
ESR
Calcium
Serum B12
Serum and urine protein electrophoresis
40 yo F
- occasional double vision
- droopy eyelids at night with
normalization by morning.
Myasthenia gravis*

Horner’s syndrome
Multiple sclerosis
Intracranial tumor compressing
CN III, IV, or VI
Amyotrophic lateral sclerosis
Tensilon test
ACh receptor antibodies (in serum)
CXR
CT—chest
MRI—brain
EMG
25 yo M
hemiparesis (after a tonic-clonic seizure) that resolves over a few hours.
Todd’s paralysis*

TIA
Stroke
Complicated migraine
Malingering
CBC, electrolytes
EEG
MRI—brain
Doppler U/S—carotid
40 yo F
Feeling tired, hopeless, and worthless and of having suicidalthoughts.
- recently found out her husband is gay
Depression*

Adjustment disorder
Hypothyroidism
Anemia
CBC
TSH
HIV/STD testing (given husband’s possible risk factors)
44 yo M
Fatigue, insomnia,and nightmares about a murder that he witnessed 1 year ago.

- avoids the mall & going out at night
Post-traumatic stress disorder
(PTSD)*

Depression
Generalized anxiety disorder
Psychotic or delusional disorder
Hypothyroidism
CBC
TSH
Calcium
Urine toxicology
55 yo M
Fatigue, weight loss, and constipation.

- family history of colon cancer.
Colon cancer*

Hypothyroidism
Renal failure
Hypercalcemia
Depression
Rectal exam, stool for occult blood
CBC, electrolytes, calcium,
BUN/Cr, AST/ALT, TSH
Colonoscopy
Barium enema
40 yo F
Fatigue, weight gain, sleepiness, cold intolerance, constipation, and dry skin.
Hypothyroidism*

Depression
Diabetes
Anemia
TSH, FT3, FT4
CBC
Glucose, HbA1c
50 yo obese F
Fatigue and daytime sleepiness.
- Snores heavily
- Naps 3–4 times per day but never feels refreshed
- Hx: HTN
Obstructive sleep apnea*

Hypothyroidism
Chronic fatigue syndrome
Narcolepsy
CBC
TSH
Nocturnal pulse oximetry
Polysomnography
ECG
20 yo M presents with fatigue, thirst,
increased appetite, and polyuria.
Diabetes mellitus*

Atypical depression
Primary polydipsia
Diabetes insipidus
Glucose tolerance test, HbA1c
UA
CBC, electrolytes, glucose
BUN/Cr
30 yo M presents with night sweats,
cough, and swollen glands of one
month’s duration.
Tuberculosis*

Acute HIV infection
Lymphoma
Leukemia
Hyperthyroidism
PPD
CBC
CXR
Sputum Gram stain, acid-fast
stain, and culture
HIV antibody
TSH, FT4
25 yo F
3-week history:
- difficulty falling asleep.
- sleeps 7 hrs w/o nightmares or snoring
- began college recently
- having trouble with boyfriend
- drinks 3-4 cups of coffee/day
Stress-induced insomnia*

Caffeine-induced insomnia
Insomnia with circadian rhythm
sleep disorder
Insomnia related to major
depressive disorder
Polysomnography
Mental status exam
Urine toxicology
CBC
TSH
55 yo obese M
Severalmonths of poor sleep and daytime
fatigue. His wife reports that he snores
loudly.
Obstructive sleep apnea*

Daytime fatigue in primary
hypersomnia
Insomnia with circadian rhythm
sleep disorder
Insomnia related to major
depressive disorder
CBC
TSH
Polysomnography
ECG
33 yo F
3 weeks of fatigue & trouble sleeping.
- falls asleep easily but wakes up at 3 am and cannot return to sleep
- unintentional weight loss: 3.5kg
- lost of interest
cannot return to sleep. She also reports
an unintentional weight loss of 3.5 kg
along with an inability to enjoy the
things she once liked to do.
Insomnia related to major
depressive disorder*

Primary hypersomnia
Insomnia with circadian rhythm
sleep disorder
Mental status exam
TSH
CBC
Polysomnography
26 yo F
Sore throat, fever, severe fatigue, and loss of appetite for 1 week

- Epigastric and LUQ discomfort
- Cervical lymphadenopathy & rash.
- boyfriend has similar symptoms
Infectious mononucleosis*

Hepatitis
Viral or bacterial
pharyngitis
Acute HIV infection
Secondary syphilis
CBC, peripheral smear
Monospot test
Throat culture
AST/ALT/bilirubin/alkaline
phosphatase
HIV antibody and viral load
Anti-EBV antibodies
VDRL/RPR
26 yo M
Sore throat, fever, rash, and weight loss.
- IV drug abuse and sharing needles.
HIV*

Infectious mononucleosis
Hepatitis
Viral pharyngitis
Streptococcal tonsillitis/
scarlet fever
Secondary syphilis
CBC
Peripheral smear
HIV antibody and viral load
CD4 count
Monospot test
Throat culture
VDRL/RPR
AST/ALT/bilirubin/alkaline
phosphatase
46 yo F presents with fever and sore
throat.
Pharyngitis (bacterial or viral)
Mycoplasma pneumonia
Acute HIV infection
Infectious mononucleosis
Throat swab for culture and rapid
streptococcal antigen
Monospot test
CBC
HIV antibody and viral load
30 yo M
shortness of breath, cough, and wheezing - worsen in cold air.
- several episodes over 4 months
Asthma
GERD
Bronchitis
Pneumonitis
Foreign body
CBC
CXR
Peak fl ow measurement
PFTs
Methacholine challenge test
56 yo F
Shortness of breath
Productive cough for 3 months each year for last 2 years
- heavy smoker
COPD—chronic bronchitis*

Bronchiectasis
Lung cancer
Tuberculosis
CBC
Sputum Gram stain and culture
CXR
PFTs
CT—chest
PPD
58 yo M
Pleuritic chest pain
- Fever & chills
- Cough with purulent yellow sputum
- heavy smoker with COPD.
Pneumonia*

Bronchitis
Lung abscess
Lung cancer
Tuberculosis
Pericarditis
CBC
Sputum Gram stain and culture
CXR
CT—chest
ECG
PPD
25 yo F
Non-productive cough - 2 weeks
Sore throat & runny nose - 3 weeks
Atypical pneumonia*

Reactive airway disease
URI-associated (“postinfectious”)
Postnasal drip
GERD
CBC
Sputum Gram stain and culture
CXR
IgM detection for Mycoplasma
pneumoniae
Urine Legionella antigen
65 yo M
Worsening cough - 6 months
- Hemoptysis
- Dyspnea
- Weakness
- Weight loss
- Heavy smoker.
Lung cancer*

Tuberculosis
Lung abscess
COPD
Vasculitis (i.e., Wegener’s)
Interstitial lung disease
CHF
CBC
Sputum Gram stain, culture, cytology
CXR
CT—chest
PPD
Bronchoscopy
55 yo M
Increased dyspnea & Sputum - 3 days
- COPD
- stopped using inhaler last week
- stopped smoking two days ago.
COPD exacerbation (bronchitis)
Lung cancer
Pneumonia
URI
CHF
CBC
CXR
PFTs
Sputum Gram stain and culture
CT—chest
34 yo F nurse
Worsening cough - 6 weeks of six
- Weight loss
- fatigue
- night sweats,
- fever
- Hx of TB contact at work
Tuberculosis*

Pneumonia
Lung abscess
Vasculitis
Lymphoma
Metastatic cancer
HIV/AIDS
Sarcoidosis
CBC
PPD
Sputum Gram stain, acid-fast
stain, and culture
CXR
CT—chest
Bronchoscopy
HIV antibody
35 yo M
Shortness of breath and cough
- Unprotected sex with multiple partners
- exposed to person with active TB
Tuberculosis Pneumonia (including
Pneumocystis jiroveci)*

Bronchitis
CHF (cardiomyopathy)
Asthma
Acute HIV infection
CBC
PPD
Sputum Gram stain, acid-fast
stain, silver stain, and culture
CXR
HIV antibody
50 yo M
Cough
- exacerbated by lying down at night
- improved by propping up on 3 pillows
- exertional dyspnea.
CHF*

Cardiac valvular disease
GERD
Pulmonary fibrosis
COPD
Postnasal drip
CBC
CXR
ECG
Echocardiography
PFTs
BNP
60 yo M
Sudden onset of substernal chest pain
- lasted for 30 minutes
- radiates to the left arm.

The pain is accompanied
- dyspnea, diaphoresis, and nausea.

Hx: HTN, hyperlipidemia, and smoking.
Myocardial infarction (MI)
GERD
Angina
Costochondritis
Aortic dissection
Pericarditis
Pulmonary embolism
Pneumothorax
ECG
CPK-MB, troponin
CXR
CBC, electrolytes
Echocardiography
Cardiac catheterization
20 yo African-American F
Acute onset of severe chest pain

Hx: Sickle cell disease
Multiple hospitalizations for
pain and anemia management.
Sickle cell disease—pulmonary
infarction*

Pneumonia
Pulmonary embolism
MI
Pneumothorax
Aortic dissection
CBC, reticulocyte count, LDH,
peripheral smear
ABG
CXR
CPK-MB, troponin
ECG
CT—chest with IV contrast
45 yo F
Retrosternal burning sensation
- starts after heavy meals & lying down
- relieved by antacids.
GERD
Esophagitis
Peptic ulcer disease
Esophageal spasm
MI
Angina
ECG
Barium swallow
Upper endoscopy
Esophageal pH monitoring
55 yo M
Retrosternal squeezing pain
- lasts for two minutes
- Occurs with exercise.
- relieved by rest
- Not related to food intake.
Angina
Esophageal spasm
Esophagitis
ECG
CPK-MB, troponin
CXR
CBC, electrolytes
Exercise stress test
Upper endoscopy/pH monitor
Cardiac catheterization
34 yo F
Retrosternal stabbing chest pain
- Improves when leans forward
- Worsens with deep inspiration
- Had a URI one week ago.
Pericarditis*

Aortic dissection
MI
Costochondritis
GERD
Esophageal rupture
ECG
CPK-MB, troponin
CXR
Echocardiography
CBC
Upper endoscopy
34 yo F
Retrosternal stabbing chest pain
- Relieved with aspirin
- Worsens with deep inspiration
- Had a URI one week ago.
- Chest wall tenderness is noted.
Costochondritis

Pneumonia
MI
Pulmonary embolism
Pericarditis
Muscle strain
ECG
CPK-MB, troponin
CXR
CBC
70 yo F
Acute onset of shortness of breath
- occurs at rest
- pleuritic chest pain.
- tachycardia, hypotension, tachypnea,
and mild fever.
- Recovering from hip replacement surgery.
Pulmonary embolism*

Pneumonia
Costochondritis
MI
CHF
Aortic dissection
ECG
CXR
ABG
CPK-MB, troponin
CBC, electrolytes
CT—chest with IV contrast
Doppler U/S—legs
D-dimer
55 yo M
sudden onset of severe chest pain
- Radiates to the back.
- Hx: uncontrolled hypertension.
Aortic dissection
MI
Pericarditis
Esophageal rupture
Esophageal spasm
GERD
Pancreatitis
Fat embolism
ECG, CPK-MB, troponin
CXR
CBC, amylase, lipase
Transesophageal
echocardiography (TEE),
MRI/MRA—aorta
Aortic angiography
Upper endoscopy
70 yo diabetic M
Episodes of palpitations and diaphoresis. He is on insulin.
Hypoglycemia*

Cardiac arrhythmias
Angina
Hyperthyroidism
Hyperventilation
episodes
Panic attacks
Pheochromocytoma
Carcinoid
Glucose
CBC, electrolytes
TSH
BUN/Cr
ECG
Holter monitor
42 yo F
7-kg weight loss - over 2 months
- a fine tremor, and her pulse is 112.
Hyperthyroidism*

Cancer
HIV infection
Dieting/diet drugs
Anorexia nervosa
Malabsorption
TSH, FT4
CBC, electrolytes
HIV antibody
Urine toxicology
44 yo F
Weight gain of > 11 kg over the past two months.
- Quit smoking 3 months ago
- Taking Amitriptyline for depression.
- Cold intolerance
- Constipation.
Smoking cessation*

Drug side effect
Hypothyroidism
Cushing’s syndrome
Polycystic ovary syndrome
Diabetes mellitus
Atypical depression
CBC, electrolytes, glucose
TSH
24-hour urine free cortisol
Dexamethasone suppression test
75 yo M
Dysphagia
- Started with solids and progressed to
liquids.
- Alcoholic
- Heavy smoker.
- Unintentional weight loss of 7 kg - 4 mo
Esophageal cancer*

Achalasia
Esophagitis
Systemic sclerosis
Esophageal stricture
Amyotrophic lateral sclerosis
CBC
CXR
Endoscopy with biopsy
Barium swallow
CT—chest
45 yo F
Dysphagia - 2 weeks
- Fatigue
- Craving for ice & clay
Plummer-Vinson syndrome*

Esophageal cancer
Esophagitis
Achalasia
Systemic sclerosis
Mitral valve stenosis
CBC
Serum iron, ferritin, TIBC
Barium swallow
Endoscopy
48 yo F
Dysphagia for both solid and liquid
- progressed over 1 year
- regurgitation of undigested food (Esp at night)
Achalasia*

Plummer-Vinson syndrome
Esophageal cancer
Esophagitis
Systemic sclerosis
Mitral valve stenosis
Esophageal stricture
Zenker’s diverticulum
CXR
Endoscopy
Barium swallow
Esophageal manometry
38 yo M p
Dysphagia and pain on swallowing solids more than liquids.
Exam reveals oral thrush.
Esophagitis (CMV, HSV, pill-induced)

Systemic sclerosis
GERD
Esophageal stricture
Zenker’s diverticulum
CBC
Endoscopy
Barium swallow
HIV antibody
CD4 count
20 yo F
Nausea, vomiting (esp in the morning), - Fatigue,
- Polyuria
- LMP - 6 weeks ago
- Breasts - full & tender
- Sexually active w/ BF. Uses condoms
Pregnancy
Gastritis
Hypercalcemia
Diabetes mellitus
UTI
Depression
Urine hCG
Pelvic exam
U/S—pelvis
CBC, electrolytes, calcium,
glucose
UA, urine culture
Baseline Pap smear, cervical
cultures, rubella antibody,
HIV antibody, hepatitis B
surface antigen, and VDRL/
RPR
45 yo M
Colicky right-sided flank pain
- Sudden onset
- Radiates to the testicles

Accompanied by
nausea, vomiting, hematuria, and CVA
tenderness.
Nephrolithiasis*

Renal cell carcinoma
Pyelonephritis
GI etiology (e.g., appendicitis)
Rectal exam
UA
Urine culture and sensitivity
BUN/Cr
CT—abdomen
U/S—renal
IVP
60 yo M
Dull epigastric pain
- Radiates to the back
- Weight loss
- Dark urine
- Clay-colored stool
- Heavy drinker and smoker.
Pancreatic cancer*

Acute viral hepatitis
Chronic pancreatitis
Cholecystitis/choledocholithiasis
Abdominal aortic aneurysm
Peptic ulcer disease
Rectal exam
CBC, electrolytes
Amylase and lipase
AST/ALT/bilirubin/alkaline
phosphatase
U/S—abdomen
CT—abdomen
56 yo M
Severe mid-epigastric abdominal pain
- radiates to the back
- improves when leans forward
- anorexia, nausea, and vomiting.
- Alcoholic - 3 days binge drinking
Acute pancreatitis*

Peptic ulcer disease
Cholecystitis/choledocholithiasis
Gastritis
Abdominal aortic aneurysm
Mesenteric ischemia
Alcoholic hepatitis
Mallory-Weiss tear
Rectal exam
CBC, electrolytes, BUN/Cr,
amylase, lipase, AST/ALT/
bilirubin/alkaline phosphatase
U/S—abdomen
CT—abdomen
Upper endoscopy
ECG
41 yo obese F
RUQ abdominal pain
- Radiates to the right scapula
- Nausea, vomiting,
- Fever of 101.5°F
- Pain starts with fatty food
- had similar episodes but less intense that lasted a few hours
- positive Murphy’s sign.
Acute cholecystitis*

Hepatitis
Choledocholithiasis
Ascending cholangitis
Peptic ulcer disease
Fitz-Hugh–Curtis syndrome
Rectal exam
CBC
AST/ALT/bilirubin/alkaline
phosphatase
U/S—abdomen
HIDA scan
43 yo obese F
RUQ abdominal pain
- Fever
- Jaundice
- Diagnosed with asymptomatic
gallstones one year ago.
Ascending cholangitis*

Acute cholecystitis
Hepatitis
Choledocholithiasis
Sclerosing cholangitis
Fitz-Hugh–Curtis syndrome
Rectal exam
CBC
AST/ALT/bilirubin/alkaline
phosphatase
Viral hepatitis serologies
U/S—abdomen
MRCP
ERCP
25 yo M
RUQ pain
- fever,
- anorexia
- nausea & vomiting.
- dark urine and clay-colored stool.
Acute hepatitis

Acute cholecystitis
Ascending cholangitis
Choledocholithiasis
Pancreatitis
Acute glomerulonephritis
Rectal exam
CBC, amylase, lipase
AST/ALT/bilirubin/alkaline
phosphatase
UA
Viral hepatitis serologies
U/S—abdomen
35 yo M
Burning epigastric pain
- starts 2–3 hours after meals.
- relieved by food and antacids.
Peptic ulcer disease*

Gastritis
GERD
Cholecystitis
Chronic pancreatitis
Mesenteric ischemia
Rectal exam
Amylase, lipase, lactate
AST/ALT/bilirubin/alkaline
phosphatase
Endoscopy (including H. pylori
testing)
Upper GI series
37 yo M
Severe epigastric pain
- nausea, vomiting,
- mild fever.
- appears toxic
- Hx: intermittent epigastric pain that is
relieved by food and antacids.
- Smokes heavily
- Takes aspirin on a regular basis.
Peptic ulcer perforation*

Acute pancreatitis
Hepatitis
Cholecystitis
Choledocholithiasis
Mesenteric ischemia
Rectal exam
CBC, electrolytes, amylase,
lipase, lactate
AST/ALT/bilirubin/alkaline
phosphatase
AXR
Upright CXR
Endoscopy (including H. pylori
testing)
18 yo M boxer
Severe LUQ abdominal pain
- radiates to the left scapula.
- He had infectious mononucleosis 3 wks ago
Splenic rupture*

Kidney stone
Rib fracture
Pneumonia
Perforated peptic ulcer
Splenic infarct
Rectal exam
CBC, electrolytes
CXR
CT—abdomen
U/S—abdomen
40 yo M
Crampy abdominal pain,
- vomiting
- abdominal distention
- inability to pass flatus or stool.
Hx: multiple abdominal surgeries.
Intestinal obstruction*

Small bowel or colon cancer
Volvulus of the bowel
Gastroenteritis
Food poisoning
Ileus
Hernia
Rectal exam
CBC, electrolytes
AXR
CT—abdomen/pelvis
CXR
70 yo F
Acute onset of severe, crampy abdominal pain.
- Vomited
- Massive dark bowel movmeent
Hx: CHF and atrial fibrillation
Meds: Digoxin
Pain is out of proportion to exam
Mesenteric ischemia/infarction*

Diverticulitis
Peptic ulcer disease
Gastroenteritis
Acute pancreatitis
Cholecystitis/choledocholithiasis
MI
Rectal exam
CBC, amylase, lipase, lactate
ECG, CPK-MB, troponin
AXR
CT—abdomen
Mesenteric angiography
Barium enema
21 yo F
Acute onset of severe RLQ pain
- nausea & vomiting.
- no fever, urinary symptoms, or
vaginal bleeding
- never taken OCP
- LMP - regular
- No hx of STD H
Ovarian torsion*

Appendicitis
Nephrolithiasis
Ectopic pregnancy
Ruptured ovarian cyst
PID
Bowel infarction or perforation
Pelvic exam
Rectal exam
Urine hCG
UA
CBC
Doppler U/S—pelvis
CT—abdomen
Laparoscopy
68 yo M
LLQ abdominal pain
- Fever & chills - 3 days
- Alternating diarrhea and constipation.
- Low fiber, high fat diet
Diverticulitis
Crohn’s disease
Ulcerative colitis
Gastroenteritis
Abscess
Rectal exam
CBC, electrolytes
CXR
AXR
CT—abdomen
20 yo M
Severe RLQ abdominal pain
- nausea, and vomiting.
- vague pain around the umbilicus - started yesterday
- As the pain worsened, it became sharp and migrated to the RLQ.
- McBurney & Psoas sign Positive
Acute appendicitis*

Gastroenteritis
Diverticulitis
Crohn’s disease
Nephrolithiasis
Volvulus or other intestinal
obstruction/perforation
Rectal exam
CBC, electrolytes
AXR
CT—abdomen
U/S—abdomen
30 yo F
Periumbilical pain - 6 months
- never awakens from sleep.
- Relieved by defecation
- Worsens when upset.
- Alternating constipation/Diarrhea
- No nausea, vomiting, weight loss, or anorexia.
Irritable bowel syndrome*

Crohn’s disease
Celiac disease
Chronic pancreatitis
GI parasitic infection
(amebiasis, giardiasis)
Endometriosis
Rectal exam, stool for occult
blood
Pelvic exam
Urine hCG
CBC
Electrolytes
CT—abdomen/pelvis
Stool for ova and parasitology,
Entamoeba histolytica
antigen
24 yo F
Bilateral lower abdominal pain
- Started with 1st day of menstrual period
- Pain w/ fever, thick, greenish-yellow vaginal discharge.
- Unprotected sex with multiple people
PID*

Endometriosis
Dysmenorrhea
Vaginitis
Cystitis
Spontaneous abortion
Pyelonephritis
Pelvic exam
Rectal exam
Urine hCG
Cervical cultures
CBC/ESR
UA, urine culture
U/S—pelvis
67 yo M
Alternating diarrhea/constipation
- decreased stool caliber
- blood in the stool - 8 months
- unintentional weight loss
- low- fiber diet
- family history of colon cancer.
Colorectal cancer*

Irritable bowel syndrome
Diverticulosis
GI parasitic infection (ascariasis,
giardiasis)
Infl ammatory bowel disease
Angiodysplasia
Rectal exam
CBC
AST/ALT/bilirubin/alkaline
phosphatase
Colonoscopy
Barium enema
CT—abdomen/pelvis
28 yo M
Constipation (veryhard stool) for the last three weeks.
- Mom died 2 months ago - ate only junk food since then
Low-fiber diet*

Irritable bowel syndrome
Substance abuse (e.g., heroin)
Depression
Hypothyroidism
Rectal exam
TSH
Electrolytes
Urine toxicology
30 yo F
Alternating constipation/diarrhea
- abdominal pain- relieved by defecation
- no nausea/vomiting, weight loss or blood in stool
Irritable bowel syndrome*

Infl ammatory bowel disease
Celiac disease
Chronic pancreatitis
GI parasitic infection (ascariasis,
giardiasis)
Lactose intolerance
Rectal exam, stool for occult
blood
CBC
Electrolytes
Stool for ova and parasitology
AXR
CT—abdomen/pelvis
33 yo M
Watery diarrhea, vomiting, diffuse abdominal pain
- 1 day history
- feels hot
- co-workers also sick
Infectious diarrhea*
(gastroenteritis)—bacterial,
viral, parasitic, protozoal

Food poisoning
Infl ammatory bowel disease
Rectal exam, stool for occult
blood
Stool leukocytes and culture
CBC
Electrolytes
CT—abdomen/pelvis
40 yo F
Watery diarrhea and abdominal cramps.
- was on antibiotics last week for UTI
Pseudomembranous colitis*
(Clostridium difficile)

Gastroenteritis
Cryptosporidiosis
Food poisoning
Infl ammatory bowel disease
Rectal exam
Stool leukocytes, culture, occult
blood
C. diffi cile toxin in stool
Electrolytes
25 yo M
Watery diarrhea and abdominal cramps. He was recently in Mexico.
Traveler’s diarrhea*

Giardiasis
Amebiasis
Food poisoning
Hepatitis A
Rectal exam
Stool leukocytes, culture,
Giardia antigen, Entamoeba
histolytica antigen
Electrolytes
AST/ALT/bilirubin/alkaline
phosphatase
Viral hepatitis serology
30 yo F
Watery diarrhea and abdominal cramping and bloating.
- aggravated by milk ingestion
- relieved by fasting.
Lactose intolerance*

Gastroenteritis
Infl ammatory bowel disease
Irritable bowel syndrome
Hyperthyroidism
Rectal exam
Stool exam
Hydrogen breath test
TSH
33 yo M
Watery diarrhea, diffuse abdominal pain, and weight loss
- 3 weeks
- has not responded to antibiotics.
Crohn’s disease*

Gastroenteritis
Ulcerative colitis
Celiac disease
Pseudomembranous colitis
Hyperthyroidism
Small bowel lymphoma
Carcinoid
Rectal exam
Stool exam and culture
CBC, electrolytes
TSH
CT—abdomen
Colonoscopy
Small bowel series
Urinary 5-HIAA
45 yo F
Coffee-ground emesis - 3 days
- Stool is dark and tarry.
- Intermittent epigastric pain that is relieved by food and antacids.
Bleeding peptic ulcer
Gastritis
Gastric cancer
Esophageal varices
Rectal exam
CBC, electrolytes
AST/ALT/bilirubin/alkaline
phosphatase
Endoscopy (including H. pylori
testing if ulcer is confi rmed)
40 yo F
Epigastric pain and coffee-ground emesis. Hx: rheumatoid arthritis - taking aspirin
- Heavy Alcoholic
Gastritis*

Bleeding peptic ulcer
Gastric cancer
Esophageal varices
Mallory-Weiss tear
Rectal exam
CBC, electrolytes
AST/ALT/bilirubin/alkaline
phosphatase
Barium swallow
Endoscopy
67 yo M
Blood in his stool
- weight loss
- constipation
- family history of colon cancer.
Colorectal cancer*

Anal fissure
Hemorrhoids
Diverticulosis
Ischemic bowel disease
Angiodysplasia
Upper GI bleeding
Inflammatory bowel disease
Rectal exam
CBC, PT/PTT
AST/ALT/bilirubin/alkaline
phosphatase
CEA
Colonoscopy
CT—abdomen/pelvis
Barium enema
33 yo F
Rectal bleeding and Diarrhea - 1 week
- Lower abdominal pain and tenesmus for
several months.
Ulcerative colitis*

Crohn’s disease
Proctitis
Anal fi ssure
Hemorrhoids
Diverticulosis
Dysentery
Rectal exam
CBC, PT/PTT
AXR
Colonoscopy
CT—abdomen/pelvis
Barium enema
58 yo M
Bright red blood per rectum
Chronic constipation.
Consumes a low-fiber diet.
Diverticulosis*

Anal fi ssure
Hemorrhoids
Angiodysplasia
Colorectal cancer
Rectal exam
CBC, PT/PTT
Electrolytes
Colonoscopy
CT—abdomen/pelvis
65 yo M
Painless hematuria.
- heavy smoker
- works as a painter.
Bladder cancer*

Renal cell carcinoma
Nephrolithiasis
Acute glomerulonephritis
Prostate cancer
Coagulation disorder (i.e., factor
VIII antibodies)
Polycystic kidney disease
Genitourinary exam
UA, urine cytology
BUN/Cr, PSA, CBC, PT/PTT
Cystoscopy
U/S—renal/bladder
CT—abdomen/pelvis
IVP
35 yo M
Painless hematuria.
- family history of kidney problems.
Polycystic kidney disease*

Nephrolithiasis
Acute glomerulonephritis (e.g.,
IgA nephropathy)
UTI
Coagulation disorder
Bladder cancer
Genitourinary exam
UA
BUN/Cr, PSA, CBC, PT/PTT
U/S—renal
CT—abdomen/pelvis
IVP
55 yo M
Flank pain and blood in his urine
- without dysuria
- weight loss and fever - 2 months
Renal cell carcinoma*

Bladder cancer
Nephrolithiasis
Acute glomerulonephritis
Pyelonephritis
Prostate cancer
Genitourinary, rectal exam
UA, urine cytology, BUN/Cr,
PSA, CBC, PT/PTT
U/S—renal
CT—abdomen/pelvis
IVP
60 yo M
Nocturia, urgency, weak stream, and terminal dribbling.
- Denies any weight loss, fatigue, or bone pain.
- 2 Episodes of urinary retention that required catheterization.
Benign prostatic hyperplasia (BPH)*

Prostate cancer
UTI
Bladder stones
Rectal exam
UA
CBC, BUN/Cr, PSA
U/S—prostate (transrectal)
71 yo M
Nocturia, urgency,
weak stream, terminal dribbling,
- hematuria & lower back pain - 4 mo
- weight loss and fatigue.
Prostate cancer*

BPH
Renal cell carcinoma
UTI
Bladder stones
Rectal exam
UA
CBC, BUN/Cr, PSA
U/S—prostate (transrectal)
CT—pelvis
IVP
18 yo M
Burning sensation during urination and urethral discharge.
- Unprotected sex with new partner
Urethritis*

Cystitis
Prostatitis
Genital ± rectal exam
UA
Urine culture
Gram stain and culture of
urethral discharge
Chlamydia and gonorrhea PCR
45 yo diabetic F
Dysuria, urinary frequency, fever, chills, and nausea over the past three days.
-left CVA tenderness
Acute pyelonephritis*

Nephrolithiasis
Renal cell carcinoma
Lower UTI (cystitis, urethritis)
UA
Urine culture and sensitivity
CBC, BUN/Cr
U/S—renal
CT—abdomen
47 yo M
Impotence - 3 months ago
- HTN - started on atenolol
- DM - on insulin
Drug-related ED*

ED caused by hypertension
ED caused by diabetes mellitus
Psychogenic ED
Peyronie’s disease
Genital exam
Rectal exam
Glucose
CBC
40 yo F

Amenorrhea,
- morning nausea and vomiting
- fatigue,
- polyuria
- LMP - 6 weeks ago
- Breasts are full and tender
- Contraception: Rhythm method
Pregnancy*

Anovulatory cycle
Hyperprolactinemia
UTI
Thyroid disease
Pelvic exam
Urine hCG
U/S—pelvis
CBC, electrolytes
UA, urine culture
Prolactin, TSH
Baseline Pap smear, cervical
cultures, rubella antibody,
HIV antibody, hepatitis B
surface antigen, and VDRL/
RPR
23 yo obese F
Amenorrhea - 6 months
- facial hair, and infertility - 3 years
Polycystic ovary syndrome*

Thyroid disease
Hyperprolactinemia
Pregnancy
Ovarian or adrenal malignancy
Premature ovarian failure
Pelvic exam
Urine hCG
U/S—pelvis
LH/FSH, TSH, prolactin
Testosterone, DHEAS
35 yo F
Amenorrhea - 6 months
- galactorrhea,
- visual field defects
- Headaches
Amenorrhea secondary to prolactinoma

Pregnancy
Thyroid disease
Premature ovarian failure
Pituitary tumor
Pelvic and breast exam
Urine hCG
Prolactin
LH/FSH, TSH
MRI—brain
48 yo F
Amenorrhea - 6 months
- hot flashes, night sweats, emotional lability, and dyspareunia.
Menopause*

Pregnancy
Pituitary tumor
Thyroid disease
Pelvic exam
Urine hCG
LH/FSH, TSH, prolactin,
testosterone, DHEAS
CBC
MRI—brain
35 yo F
Amenorrhea
- cold intolerance
- coarse hair
- weight loss
- fatigue
Hx: abruptio placentae followed by hypovolemic shock
and failure of lactation two years ago.
Sheehan’s syndrome*

Premature ovarian failure
Pituitary tumor
Thyroid disease
Asherman’s syndrome
Pelvic exam
Urine hCG
CBC
LH/FSH, prolactin
TSH, FT4
ACTH
MRI—brain
Hysteroscopy
18 yo F
Amenorrhea - 4 months
- lost 95 pounds
- history of vigorous exercise and
cold intolerance.
Anorexia nervosa
CBC
TSH
FT4
ACTH
FSH
LH
29 yo F
Amenorrhea - 6 months
- occasional palpitations and dizziness. - lost her fiancé in a car accident.
Anxiety-induced amenorrhea
CBC
TSH
FT4
ACTH
Urine cortisol level
Progesterone challenge test
FSH/LH/estradiol levels
17 yo F
prolonged, excessive menstrual bleeding occurring irregularly over the past six months.
Dysfunctional uterine bleeding*

Coagulation disorders (e.g., von
Willebrand’s disease,
hemophilia)
Cervical cancer
Molar pregnancy
Hypothyroidism
Diabetes mellitus
Pelvic exam
Urine hCG
Cervical cultures, Pap smear
CBC, ESR, glucose
PT/PTT
Prolactin, LH/FSH
TSH
U/S—pelvis
61 yo obese F
Profuse vaginal bleeding - 1 month
- LMP - 10 years
- Hx: HTN, DM
- Nulliparous
Endometrial cancer*

Cervical cancer
Atrophic endometrium
Endometrial hyperplasia
Endometrial polyps
Atrophic vaginitis
Pelvic exam
Pap smear
Endometrial biopsy
U/S—pelvis
Endometrial curettage
Colposcopy
Hysteroscopy
45 yo G5P5 F
Postcoital bleeding.
- cigarette smoker
- takes OCPs.
Cervical cancer
Cervical polyp
Cervicitis
Trauma (e.g., cervical laceration)
Pelvic exam
Pap smear
Colposcopy and biopsy
28 yo F - 8 weeks pregnant
Lower abdominal pain and vaginal bleeding.
Spontaneous abortion*

Ectopic pregnancy
Molar pregnancy
Pelvic exam
Urine hCG
U/S—pelvis
CBC, PT/PTT
Quantitative serum hCG
32 yo F
Left lower abdominal pain
- Sudden onset
- Radiates to the scapula and back
- vaginal bleeding.
- LMP: 5 weeks ago
- Hx: PID
- Does not use protection
Ectopic pregnancy*

Ruptured ovarian cyst
Ovarian torsion
PID
Pelvic exam
Urine hCG
Cervical cultures
U/S—pelvis
Quantitative serum hCG
28 yo F
thin, grayish-white, foul-smelling vaginal discharge.
Bacterial vaginosis*

Vaginitis—candidal
Vaginitis—trichomonal
Cervicitis (chlamydia, gonorrhea)
Pelvic exam
Wet mount
Cervical cultures
KOH prep (“whiff test”)
pH of vaginal fl uid
30 yo F
Thick, white, cottage cheese–like, odorless vaginal discharge and vaginal itching.
Vaginitis—candidal*

Bacterial vaginosis
Vaginitis—trichomonal
Pelvic exam
KOH prep (“whiff test”)
Wet mount
Cervical cultures
pH of vaginal fl uid
35 yo F
malodorous, profuse, frothy, greenish vaginal discharge
- intense vaginal itching and discomfort.
Vaginitis—trichomonal*

Vaginitis—candidal
Bacterial vaginosis
Cervicitis (chlamydia,
gonorrhea)
Pelvic exam
Wet mount
Cervical cultures
pH of the vaginal fl uid
KOH prep (“whiff test”)
54 yo F
Painful intercourse
- LMP: 9 months ago
- Hot flashes
Atrophic vaginitis*

Endometriosis
Cervicitis
Depression
Domestic abuse
Pelvic exam
Wet mount, KOH prep, cervical
cultures
U/S—pelvis
37 yo F
Dyspareunia, inability to conceive, and dysmenorrhea.
Endometriosis*

Cervicitis
Vaginismus
Vulvodynia
PID
Depression
Domestic violence
Pelvic exam
Wet mount, KOH prep, cervical
cultures
U/S—pelvis
Laparoscopy
28 yo F
multiple facial and bodily injuries.
- claims she fell down the stairs
- hospitalized for physical injuries seven months ago.
- Presents with husband
Domestic violence*

Osteogenesis imperfecta
Substance abuse
Consensual violent sexual
behavior
XR—skeletal survey
CT—maxillofacial
Urine toxicology
CBC
30 yo F
Multiple facial and physical injuries.
- Was attacked and raped by two men.
Rape
Pelvic exam
Urine hCG
Wet mount, KOH prep, cervical
cultures
XR—skeletal survey
CBC
HIV antibody
Viral hepatitis serologies
30 yo F
Wrist pain and a black eye after tripping, falling, and hitting her head on the edge of a table.

- looks anxious and gives an
inconsistent story.
Domestic violence
Factitious disorder
Substance abuse
XR—wrist
CT—head
Urine toxicology
30 yo F secretary
Wrist pain
- sensation of numbness and burning
in her palm and the first, second, and
third fingers of her right hand.
- pain worsens at night
- relieved by loose shaking of the hand. - Sensory loss in the same fingers.
- Positive Tinel’s sign.
Carpal tunnel syndrome*

Median nerve compression in
forearm or arm
Radiculopathy of nerve roots C6
and C7 in cervical spine
Nerve conduction study
EMG
28 yo F
Pain in the interphalangeal joints of hands
- hair loss
- butterfly rash on her face.
Systemic lupus erythematosus (SLE)*

Rheumatoid arthritis
Psoriatic arthritis
Parvovirus B19 infection
ANA, anti-dsDNA, ESR, C3,
C4, rheumatoid factor (RF),
CBC
XR—hands
UA
28 yo F
metacarpophalangeal joint pain in both hands.
- Left knee - painful and red
- Morning joint stiffness - last 1 hour
- FHx: mother had rheumatoid arthritis.
Rheumatoid arthritis*

SLE
Disseminated gonorrhea
Arthritis associated with inflammatory bowel disease
Osteoarthritis
ANA, anti-dsDNA, ESR, RF,
CBC
XR—hands, left knee
Cervical culture
Arthrocentesis and synovial
fluid analysis
18 yo M
Interphalangeal joint pain of both hands
- scaly, salmon-pink lesions on
extensor surface of his elbows and knees.
Psoriatic arthritis*

Rheumatoid arthritis
SLE
RF, ANA, ESR
CBC
XR—hands
XR—pelvis/sacroiliac joints
Uric acid
65 yo F
Unable to use Left leg or bear weight on it
- Tripped on carpet
- Menopause 20 years ago
- No HRT or Calcium supplements
- Left leg is externally rotated, shortened, and adducted, and there is tenderness in her left groin.
Hip fracture*

Hip dislocation
Pelvic fracture
XR—hip/pelvis
CT or MRI—hip
CBC
Serum calcium and vitamin D
Bone density scan (DEXA)
40 yo M
Right groin pain
- after a motor vehicle accident
- Right leg is flexed at the hip, adducted,
and internally rotated.
Hip dislocation—traumatic*

Hip fracture
XR—hip
CT or MRI—hip
CBC
PT/PTT
Blood type and cross-match
Urine toxicology and blood
alcohol level
56 yo obese F
Right knee stiffness
- Pain that increases with movement.
- Worsened over 10 years.
- Swelling and deformity of joint
- Difficulty walking.
Osteoarthritis*

Pseudogout
Gout
Meniscal or ligament damage
XR—knee
CBC
ESR
Knee arthrocentesis and
synovial fl uid analysis (cell
count, Gram stain, culture,
crystals)
MRI—knee
45 yo M
Right knee pain with swelling and redness.
Septic arthritis*

Gout
Pseudogout
Lyme arthritis
Trauma
Reiter’s arthritis
CBC
Knee arthrocentesis and
synovial fl uid analysis (see
above)
Blood, urethral cultures
XR—knee
Uric acid
Lyme antibody
65 yo M
Right foot pain.
- been training for a marathon.
Stress fracture*

Plantar fasciitis
Foot sprain or strain
XR—foot
Bone scan—foot
MRI—foot
65 yo M
Heel pain on right foot
- worse w/ 1st few steps
- improved with continued walking
- no known trauma
Plantar fasciitis*

Heel fracture
Splinter/foreign body
XR—heel
Bone scan
55 yo M
Elbow Pain - when plays tennis
- grip impaired b/c of pain
- Tenderness over lateral epicondyl
- Pain on resisted wrist dorsiflexion
(Cozen’s test) with the elbow in
extension.
Tennis elbow (lateral epicondylitis)*

Stress fracture
XR—arm
Bone scan
MRI—elbow
27 yo F
Painful wrists and elbows
- Swollen & hot knee joint- painful on flexion
- Rash on her limbs
- Vaginal discharge
- Sexually active w/ multiple partners
- occasionally uses condoms.
Disseminated gonorrhea*

Rheumatoid arthritis
SLE
Psoriatic arthritis
Reiter’s arthritis
Knee arthrocentesis and
synovial fl uid analysis (cell
count, Gram stain, culture)
ANA, anti-dsDNA, ESR, RF,
CBC
Blood, cervical cultures
XR—knee
60 yo F
Bilateral leg pain
- Induced by walking
- Relieved by rest
- Hx: cardiac bypass surgery - 6 mo
- Heavy Smoker
Peripheral vascular disease*
(intermittent claudication)

Leriche’s syndrome (aortoiliac
occlusive disease)
Lumbar spinal stenosis
(pseudoclaudication)
Osteoarthritis
Ankle-brachial index
Doppler U/S—lower extremity
Angiography
MRI—lumbar spine
45 yo F
Right calf pain
- Calf is tender, warm, red, and swollen
compared to the left side.
- Started OCP for dysfunctional uterine bleeding - 2 months ago
DVT*

Baker’s cyst rupture
Myositis
Cellulitis
Superfi cial venous thrombosis
Doppler U/S—right leg
CBC
CPK
D-dimer
PT, aPTT, fi brinogen
XR—right leg
60 yo F
Left arm pain
- started when swimming
- relieved by rest.
Angina/MI*

Tendonitis
Osteoarthritis
Shoulder dislocation
CPK-MB, troponin, ECG
CBC
ESR
XR—shoulder
CXR
Echocardiography
Stress test
50 yo M
Right shoulder pain
- FOOSH when skiing
- Deformity of his shoulder
- Has to hold his right arm
Shoulder dislocation*

Fracture of the humerus
Rotator cuff injury
XR—shoulder
XR—arm
MRI—shoulder
55 yo M
Crampy bilateral thigh and calf pain,
- fatigue
- dark urine
- simvastatin and clofibrate
for hyperlipidemia.
Rhabdomyolysis due tosimvastatin or clofibrate*

Polymyositis
Inclusion body myositis
Thyroid disease
CBC
CPK
Aldolase
UA
Urine myoglobin
TSH
45 yo F
Low back pain
- radiates to lateral aspect of left foot.
- Straight leg raising is positive.
- Patient is unable to tiptoe.
Disk herniation*

Lumbar muscle strain
Tumor in the vertebral canal
XR—L-spine
MRI—L-spine
45 yo F
Low back pain
- started after she cleaned her house.
- pain does not radiate
- no sensory deficit or weakness in legs.
- Paraspinal muscle tenderness and spasm
Lumbar muscle strain*

Disk herniation
Abdominal aortic aneurysm
Vertebral compression fracture
XR—L-spine
45 yo M
Pain in the lower back and legs during prolonged standing and walking.
- Relieved by sitting and leaning forward
Lumbar spinal stenosis*

Lumbar muscle strain
Tumor in the vertebral canal
Peripheral vascular disease
XR—L-spine
MRI—L-spine
(preferred)
CT—L-spine
Ankle-brachial index
17 yo M
Low back pain
- Radiates to the left leg
- Began after fell on his knee during gym class.
- loss of sensation in left foot.
- The pain and sensory loss do not
match any known distribution.
- Insists on requesting a week off from school
because of his injury.
Malingering*

Lumbar muscle strain
Disk herniation
Knee or leg fracture
Ankylosing spondylitis
XR—L-spine/knee
MRI—L-spine
20-day-old M
Fever,
- decreased breast-feeding,
- lethargy
- born at 36 weeks as a result of
premature rupture of membranes.
Neonatal sepsis*

Meningitis
Pneumonia
UTI
Physical exam
CBC, electrolytes
UA
Urine culture
Blood culture
CXR
LP—CSF analysis
3 yo M
Fever & Pulling right ear - 2 days
- Otherwise healthy
- Immunizations UTD
- Attends daycare
- Older sister had a cold
Acute otitis media*

URI
Meningitis
UTI
Physical exam (including
pneumatic otoscopy)
CBC
UA
12-month-old M
Fever - 2 days
- Maculopapular rash on face &body
- Did not receive MMR vaccine
Measles (or other viral exanthem)*

Rubella
Roseola
Fifth disease
Varicella
Scarlet fever
Meningitis
Physical exam
CBC
Viral antibodies/titers
Throat swab for culture
LP
4 yo M
Fever
- Diarrhea & vomiting,
- Lethargy & weaknes
- Attends daycare - multiple kids with similar symptoms
Gastroenteritis (viral, bacterial,
parasitic)*

Food poisoning
UTI
URI
Volvulus
Intussusception
Physical exam
Stool exam and culture
CBC
Electrolytes
UA, urine culture
AXR
9 yo M
Angry Outburst - 2 years
- at home & school
- runs around "as if driven by motor"
- does not sit down in class
- interrupts classmates
- trouble making friends
Attention-deficit hyperactivity disorder (ADHD)*

Oppositional defiant disorder
Manic episode
Conduct disorder
Physical exam
Mental status exam
12 yo F
2 Month history of:
- Fighting in School,
- Truancy
- Breaking curfew

- Recently divorced parents
- recently moved to new school district
- was average student before divorce
Adjustment disorder*

Substance intoxication/abuse/
dependence
Manic episode
Oppositional defi ant disorder
Conduct disorder
Physical exam
Mental status exam
Urine toxicology
15 yo M
1 year history of:
- Failing grades
- School absenteeism
- Legal problems, including shoplifting.

spends most of his time alone in his room
- when he goes out, its with a new group of friends
Substance abuse*

Conduct disorder
Oppositional defi ant disorder
Adjustment disorder
Urine toxicology
Mental status exam
5 yo M
6 Month history:
-Temper tantrums - last 5–10 minutes that follows disappointment or a discipline.
- No problems sleeping
- No change in appetite
- Does not display behavior when at day care
Age-appropriate behavior

ADHD
Oppositional defi ant disorder
Physical exam
Mental status exam