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14 Cards in this Set
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- 3rd side (hint)
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Complications Crohns
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Obstruction & perforation of the Small intestine
Absecesses Fistulae Intestinal Bleeding Massive distention of the colon & rupture of the intestine |
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Diagnostics
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Pts with fever abdominal pain and tenderness diarrhea w/ wo bleeding anal disease
Elevated WBC Elevated Sed Rate Anemia Low blood proteins Video Capsule endoscopy |
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Treatment
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Induce remision Maintain remission minimize side effets of tretmet improve quality of life
anti-inflammatories topical antibiotics corticosteroids immune modulators fluctuate between relapse and remission |
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Azulfidine
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Side effects nauseaheartburn headache anemia skin rashes hepatitis kidney inflammation reduced sperm count
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Rowasa
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Form of 5-ASA rectal enema
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corticosteroids
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Used to treat moderate to severe Crohns side effects moon face acne increased body hair diabetes wt gain HTN cataracts glaucoma, susceptibility to infections muscle weakness depression insomnia mood swings Must wean off drugs slowly
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Budesonide
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corticosteroid for treating crohns that has to have contact with diseased tissue to be effective. Used in terminal patients
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Cipro/Flagyl
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Crohs colitis and anal fistulae
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Immuno Modulators
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Azathiopine (imuran ) Weekens body's immune system side effects include increased vulerability to infection Inflammation of the liver and the pancreas and bone marrow toxicity
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Remicade
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Decreases the inflammatory response by attaching to the tumor necrosing factor released by immune cellls and blocking its inflammatory response in the body
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Infliximab
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Infusions every 8 wks 1-2 yrs maintain remission of Crohns. Healing the ulcerative and fistulae effects of the disease. Aggravate infection, not given to pts with abscesses
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Methotrexate
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An immune modulator and anti infammatory. Given po or sq monitor for liver cirrhosis
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Surgery in Crohns
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Used for removal of diseased segment of small intestine that is obstructed drainage of us from abdominal and peri rectal abscesses, fistulae that do not respond to drugs resection of internal fistulae causing infections.
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Diet
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Low fiber
TPN when the intestine needs to rest supplements of calcium folate vitamin B12 anti diarrheals and anti spasmodics |
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