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177 Cards in this Set
- Front
- Back
Section of the nervous system that is composed of gray and white matter
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CNS, brain and spinal cord
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Composed of nerve cell bodies
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Gray matter
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Composed of myelinated axons
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White matter
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Group of nerve fibers within the CNS with a common origin and an common destination
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Nerve Tract
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Cluster of nerve cell bodies within the CNS
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Nucleus
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Nervous tissue outside the brain and spinal cord
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PNS
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the PNS contains _____ pairs of cranial nerves
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12
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The PNS contains _____ pairs of spinal nerves
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31
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A group of nerve fibers in the PNS with a common origin and common destination
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Nerve
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A cluster of nerve cell bodies in the PNS
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Ganglion
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Junction between neurons
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Synapse
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Two divisions of the autonomic nervous system
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Sympathetic and Parsympathetic
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Glial cells that make the BBB
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astrocytes
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Glial cells that line cavities
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Ependymal
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Glial cells that make phagocytes
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microglia
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Glial cells that form myelin
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oligodendrocytes, schwann cells
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Nervous sytem that is involuntary
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autonomic
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Nervous system that is voluntary
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Somatic
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Pathology of the brain causing paralysis, lack of coordination, and other dysfunctions of motor and sensory mechanisms
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Cerebral Palsy
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Permanent paralysis of both legs due to injury or disease of the spinal cord
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Paraplegia
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Permanent paralysis of arms and legs due to spinal cord injury or certain diseases
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Quadriplegia
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Enlarged portion of the neuron containing the nucleus
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Cell body
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Cytoplasmic extensions which receive stimuli and conduct impulses to the cell body
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Dendrites
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Cylindrical processes that conduct impulses away from the cell body
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Axons
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Myelinate the PNS
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Schwann Cells
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Myelinate the CNS
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Oligodendrocytes
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Segments in the myelin sheath
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Node of Ranvier
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Transmit impulses to the CNS
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Afferent
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Conduct impulses between the sensory and motor neurons
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Interneurons
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Conduct impulses away from the CNS
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Efferent
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Has one axon and two or more dendrites
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Multipolar
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Has one axon and one dendrite
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Bipolar
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Has a single process which branches into an axon and a dendrite
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Unipolar
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A chronic degenerative disorder of the myelin sheath in the CNS
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MS
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Inherited disease in which the myelin sheaths are destroyed by excessive accumulation of lipids within the membrane layers
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Tay-Sachs disease
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During resting membrane potential there are more anions _____ the cell
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Inside
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The sodium-potassium pump transport Na+ _____ and K+ ____
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outside, inside
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The cell membrane is essentially impermeable to ______ which are present inside the neuron
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large proteins
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The _____ of action potentials constitute the code as well as the destination of the impulse
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frequency
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Action potential are similar in all organisms T/F
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T
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Average resting membrane potential
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-70 mV
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Process of action potential
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Stimulus > Open Na+ channels > Na+ moves inside > All or none > Depolarization > Reverse Polarization > Open K+ channels > Repolarization > Resting membrane potential
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During the interval from the onset of an action potential until repolarization is about 1/3 completed, and a 2nd stimulation cannot elicit another response
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Absolute Refractory Period
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The period after the absolute refractory period when the membrane will not respond to normal stimuli, but does to very strong stimulus that can depolarize the membrane
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Relative Refractory Period
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2 chemicals that block the Na+ pores
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TTX and Saxitoxin
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Chemical that keeps the Na+ pores open
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Batrachotoxin
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When impulses move in one direction, the correct direction
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Orthodromic
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When impulses move in the wrong direction
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Antidromic
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Leaping from node to node
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Saltatory conduction
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2nd most common nervous system disease next to epilepsy
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MS
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Most common symptoms of MS
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blurred vision, impeded speech, numbness, fatigue
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Physically block sodium channels
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Local anesthetics
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2 types of synapses
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electrical and chemical
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Small round or oval knobs on the axon
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axon terminal
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Microscopic space between two neurons
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Synaptic cleft
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2 main types of neurotransmitters located in the synaptic vesicles
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ACh, Norepi
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Cell membrane of the postsynaptic neuron which contains receptors for the neurotransmitters
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Postsynaptic membrane
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Process
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Look in Notes
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Breaks down ACh
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cholinesterase
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3 characteristics of a synapse
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Delay, Fatigue, One way conducting
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Lack of neurotransmitter dopamine
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Parkinsons
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Autoimmune disease that blocks the ACh receptors
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Myasthenia
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Disease that inhibits release of ACh
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Botulism
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An anti-cholinesterase that causes the muscles to stay contracted
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Nerve gas
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Several presynaptic neurons simultaneously releasing neurotransmitters to a single postsynaptic neuron
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Spatial Summation
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The EPSP's may summate as the result of the rapid successive discharge of neurotransmitter from the same presynaptic terminal
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Temporal Summation
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When the postsynaptic membrane becomes more permeable to Na and K ions, resulting in hyperpolarization
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IPSP
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An amino acid that is a neurotransmitter involved in IPSP's
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Glycine
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Glutamate, GABA, Glycine, Asparate
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Amino Acids
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Histamine, Dopamine, Serotonin, Norepinephrine, Epinephrine
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Amines
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Substance P, Endorphins, Enkephalins
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Polypeptides
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Nitric Oxide
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Gas
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Connects the two cerebral hemispheres, made up of 300 million neural axons
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Corpus Callosum
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Motor area, elaborate thought, speaking ability
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Frontal Lobe
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Sensory area, somesthetic, proprioception
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Parietal Lobe
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Hearing
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Temporal Lobe
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Visual input
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Occipital Lobe
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Fold or convolutions of the brain
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Gyri
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Grooves or valleys
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Fissures or Sulci
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3 Main sulci in the brain
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Longitudinal, Central, Lateral
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Largest and most prominent part of the brain
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Cerebrum
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Outer portion of the cerebrum, gray matter
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Cerebral Cortex
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Recognition of crude sensations, pain, temperature, touch. Feeling of pleasure and displeasure
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Thalamus
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Water balance, controls the pituitary, body temperature, apetite and food intake
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Hypothalamus
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Controls muscle action, posture, equilibrium
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Cerebellum
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Control HR, BP, respiration, coughing, etc.
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Medulla Oblongata
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Center for 5th, 6th, 7th, and 8th cranial nerves
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Pons
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Center for 3rd and 4th cranial nerves
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Midbrain
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Two main ideas of the BBB
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Astrocytes; help neurons, tight juncionts
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Number of cervical nerves
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8
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Number of thoracic nerves
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12
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Number of Lumbar nerves
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5
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Number of sacral nerves
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5
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Number of coccygeal nerves
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1
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Cranial Nerve 1 and function
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Olfactory; smell
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Cranial nerve 5 and function
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Trigeminal; Sensation of the face, teeth and tongue, movement of jaw and chewing muscles
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Cranial nerve 7 and function
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Facial; taste buds at front of tongue, secretion of saliva and tears
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Cranial nerve 8 and function
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Vestibulocochlear; Hearing, balance, posture
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Cranial nerve 9
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Glossopharyngeal; taste bud in the back, swallowing, secretion of saliva
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Cranial nerve 10 and function
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Vagus; visceral sensation and movement
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Cranial nerve 11
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Accessory; swallowing and head and neck movements
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Cranial nerve 12
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Speech and swallowing
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Forms the letter H at the center of the spinal cord
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Gray matter
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Composed of neuron cell bodies
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Gray matter
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All ascending nerves are _____ and all descending nerves are _____.
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sensory, motor
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Anterior tract conducts
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touch and pressure
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Posterior tract conducts
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pain and temperature
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8-12 waves per second
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Alpha
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12-25 waves per second
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Beta
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5-8 waves per second
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Theta
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1-5 waves per second
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Delta
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Cessation of brain waves
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Brain death
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Unresponsive, flat EEG for 10 minutes, absence of CNS reflexes, absence of non-spontaneous unassisted repiration
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Brain Death
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A slightly alkaline solution containing more Na, Cl, and Mg than blood plasma and less of Ca, K, and COH
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CSF
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Produces CSF
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Chorochoid Plexus
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Pathway of flow of CSF
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Lateral Ventricles > Interventricular Foramen > 3rd Ventricle > Cerebral Aqueduct > 4th Ventricle > Subarachnoid Space > Reabsorption at the Arachnoid villi
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Main function of CSF
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Cushion the brain
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Cause by excessive production of or blocked flow of CSF
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Hydrocephalus
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Withdrawal of CSF from the subarachnoid space
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Lumbar Puncture
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2 reason for a lumbar puncture
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CSF is used to check for infection to identify the organism and determine the correct drug that will fight it and cross the BBB, and to check for clots or RBC rupture in the brain
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Obstruction of CSF flow and aqueduct stenosis
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Noncommunicating
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Increase CSF secretion and secreting tumor
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Communicating
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Waves that occur during rest
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Alpha
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Waves that occur during nonREM
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Delta
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3 types of muscles that are controls by the autonomic nervous system
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Cardiac, Smooth, Visceral
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2 divisions of the autonomic nervous system
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Sympathetic, Parasympathetic
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Main neurotransmitter of the sympathetic nervous system
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NE
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Main neurotransmitter of the parasympathetic nervous system
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ACh
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Has long preganglionic neuron and short postganglionic neuron
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Parasympathetic
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Has short preganglionic neuron and long postganglionic neuron
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Sympathetic
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Origin of the sympathetic nervous system
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Thoracolumbar (T1-T12 and L1 to L3)
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Origination of parasympathetic nervous system
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Craniosacral (3,7,9,10)
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Receptor located at the ganglia of the sympathetic and parasympthetic nervous systems
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Nicotinic
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Receptor located at the effector organ in the parasympathetic nervous system
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Muscarinic
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Receptor located at the effector organ of the sympathetic nervous system
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Alpha 1, Beta 1, Beta 2
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The most common type of muscarinic receptor antagonist
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Atropine
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4 muscarinic receptor stimulants
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ACh, Carbachol, Methacholine, Bethanechol
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Catecholamines releases from the Adrenal gland
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80% Epinephrine, 20% NE
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Located in the smooth muscle, cause vasoconstriction, etc.
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Alpha 1 receptors
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Located in the heart, causes increase rate and force of contraction
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Beta 1 receptors
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Located in the smooth muscle, causes vasodilation of lungs, etc.
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Beta 2 receptors
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Cause vasoconstriction, are used as decongestants
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Alpha receptor stimulators
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Are used to lower blood pressure
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Alpha receptor blockers
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Used to stimulate the heart and cause bronchodilation
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Beta receptor stimulators
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Are used to slow the heart
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Beta blockers
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Sensors dealing with touch, deep pressure, hearing, etc. Detect mechanical deformation or the receptor or cells near the receptor
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Mechanoreceptors
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Detect change in temperature, stimulated by changes in metabolic rate
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Thermoreceptors
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Pain receptors, detect damage to tissue
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Nociceptors
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Detect light on the retina of the eye
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Photoreceptors
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Detect taste in mouth, smell, and O2 and CO2 levels in the blood
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Chemoreceptors
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Sensors that do not adapt at all or very slowly
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Tonic
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Sensors that adapt rapidly, usually no longer responding to a maintained stimulus
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Phasic
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Pain that is localized on the surface of the body
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Cutaneous
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Pain from muscles, tendons, and joints
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Deep
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Pain from organs, poorly localized
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Visceral
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In response to pain, exercise, or stress, the body releases ____ and ______
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Endorphins, Enkaphalins
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Pain that deals with embryonic origin and crossover of 1st and 2nd order neuorons
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Referred Pain
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Uncontrolled discharge of activity my neurons in the brain
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Epilespy
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A single motor neuron and muscle fibers it innervates
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Motor Unit
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The space between the nerve and the muscle membrane
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Myoneural junction
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Muscle cells are elongated, lack striations, are under involuntary control, and have one nucleus which is located at the center of each cell
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Smooth Muscle
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Muscle fibers that have cross-striations and one centrally located nucleus, and are under involuntary control
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Cardiac Muscle
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Muscle cell fibers are elongated, multinucleate, under voluntary control, have well-develope striations
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Skeletal Muscle
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From Z-line to Z-line
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Sarcomere
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Many small, round parallel bundles
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Myofibrils
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Thin filaments
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Actin
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Thick filaments
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Myosin
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Actin that is in clumps
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G-actin
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Actin that is in a double spherical chain
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F-actin
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ATP binds to _____ causing detachment of the Ca++
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HMM
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Binds up to 43 Ca++ within the sarcoplasmic reticulum
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Calsequestrin
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ATP is necessary for the
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cross bridging
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3 phases of the muscle twitch
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Latent period, contraction period, and relaxation period
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Muscle contracts but doesn't lengthen or shorten
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Isometric
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Muscle shortens while the load on the muscle remains constant
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Isotonic
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Causes of muscle fatigue
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ATP depletion, COH depletion, Lactic Acid build up
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Reason why cardiac muscle cells cannot undergo tetanus
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They have long absolute and relative refractory periods.
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