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177 Cards in this Set

  • Front
  • Back
Section of the nervous system that is composed of gray and white matter
CNS, brain and spinal cord
Composed of nerve cell bodies
Gray matter
Composed of myelinated axons
White matter
Group of nerve fibers within the CNS with a common origin and an common destination
Nerve Tract
Cluster of nerve cell bodies within the CNS
Nucleus
Nervous tissue outside the brain and spinal cord
PNS
the PNS contains _____ pairs of cranial nerves
12
The PNS contains _____ pairs of spinal nerves
31
A group of nerve fibers in the PNS with a common origin and common destination
Nerve
A cluster of nerve cell bodies in the PNS
Ganglion
Junction between neurons
Synapse
Two divisions of the autonomic nervous system
Sympathetic and Parsympathetic
Glial cells that make the BBB
astrocytes
Glial cells that line cavities
Ependymal
Glial cells that make phagocytes
microglia
Glial cells that form myelin
oligodendrocytes, schwann cells
Nervous sytem that is involuntary
autonomic
Nervous system that is voluntary
Somatic
Pathology of the brain causing paralysis, lack of coordination, and other dysfunctions of motor and sensory mechanisms
Cerebral Palsy
Permanent paralysis of both legs due to injury or disease of the spinal cord
Paraplegia
Permanent paralysis of arms and legs due to spinal cord injury or certain diseases
Quadriplegia
Enlarged portion of the neuron containing the nucleus
Cell body
Cytoplasmic extensions which receive stimuli and conduct impulses to the cell body
Dendrites
Cylindrical processes that conduct impulses away from the cell body
Axons
Myelinate the PNS
Schwann Cells
Myelinate the CNS
Oligodendrocytes
Segments in the myelin sheath
Node of Ranvier
Transmit impulses to the CNS
Afferent
Conduct impulses between the sensory and motor neurons
Interneurons
Conduct impulses away from the CNS
Efferent
Has one axon and two or more dendrites
Multipolar
Has one axon and one dendrite
Bipolar
Has a single process which branches into an axon and a dendrite
Unipolar
A chronic degenerative disorder of the myelin sheath in the CNS
MS
Inherited disease in which the myelin sheaths are destroyed by excessive accumulation of lipids within the membrane layers
Tay-Sachs disease
During resting membrane potential there are more anions _____ the cell
Inside
The sodium-potassium pump transport Na+ _____ and K+ ____
outside, inside
The cell membrane is essentially impermeable to ______ which are present inside the neuron
large proteins
The _____ of action potentials constitute the code as well as the destination of the impulse
frequency
Action potential are similar in all organisms T/F
T
Average resting membrane potential
-70 mV
Process of action potential
Stimulus > Open Na+ channels > Na+ moves inside > All or none > Depolarization > Reverse Polarization > Open K+ channels > Repolarization > Resting membrane potential
During the interval from the onset of an action potential until repolarization is about 1/3 completed, and a 2nd stimulation cannot elicit another response
Absolute Refractory Period
The period after the absolute refractory period when the membrane will not respond to normal stimuli, but does to very strong stimulus that can depolarize the membrane
Relative Refractory Period
2 chemicals that block the Na+ pores
TTX and Saxitoxin
Chemical that keeps the Na+ pores open
Batrachotoxin
When impulses move in one direction, the correct direction
Orthodromic
When impulses move in the wrong direction
Antidromic
Leaping from node to node
Saltatory conduction
2nd most common nervous system disease next to epilepsy
MS
Most common symptoms of MS
blurred vision, impeded speech, numbness, fatigue
Physically block sodium channels
Local anesthetics
2 types of synapses
electrical and chemical
Small round or oval knobs on the axon
axon terminal
Microscopic space between two neurons
Synaptic cleft
2 main types of neurotransmitters located in the synaptic vesicles
ACh, Norepi
Cell membrane of the postsynaptic neuron which contains receptors for the neurotransmitters
Postsynaptic membrane
Process
Look in Notes
Breaks down ACh
cholinesterase
3 characteristics of a synapse
Delay, Fatigue, One way conducting
Lack of neurotransmitter dopamine
Parkinsons
Autoimmune disease that blocks the ACh receptors
Myasthenia
Disease that inhibits release of ACh
Botulism
An anti-cholinesterase that causes the muscles to stay contracted
Nerve gas
Several presynaptic neurons simultaneously releasing neurotransmitters to a single postsynaptic neuron
Spatial Summation
The EPSP's may summate as the result of the rapid successive discharge of neurotransmitter from the same presynaptic terminal
Temporal Summation
When the postsynaptic membrane becomes more permeable to Na and K ions, resulting in hyperpolarization
IPSP
An amino acid that is a neurotransmitter involved in IPSP's
Glycine
Glutamate, GABA, Glycine, Asparate
Amino Acids
Histamine, Dopamine, Serotonin, Norepinephrine, Epinephrine
Amines
Substance P, Endorphins, Enkephalins
Polypeptides
Nitric Oxide
Gas
Connects the two cerebral hemispheres, made up of 300 million neural axons
Corpus Callosum
Motor area, elaborate thought, speaking ability
Frontal Lobe
Sensory area, somesthetic, proprioception
Parietal Lobe
Hearing
Temporal Lobe
Visual input
Occipital Lobe
Fold or convolutions of the brain
Gyri
Grooves or valleys
Fissures or Sulci
3 Main sulci in the brain
Longitudinal, Central, Lateral
Largest and most prominent part of the brain
Cerebrum
Outer portion of the cerebrum, gray matter
Cerebral Cortex
Recognition of crude sensations, pain, temperature, touch. Feeling of pleasure and displeasure
Thalamus
Water balance, controls the pituitary, body temperature, apetite and food intake
Hypothalamus
Controls muscle action, posture, equilibrium
Cerebellum
Control HR, BP, respiration, coughing, etc.
Medulla Oblongata
Center for 5th, 6th, 7th, and 8th cranial nerves
Pons
Center for 3rd and 4th cranial nerves
Midbrain
Two main ideas of the BBB
Astrocytes; help neurons, tight juncionts
Number of cervical nerves
8
Number of thoracic nerves
12
Number of Lumbar nerves
5
Number of sacral nerves
5
Number of coccygeal nerves
1
Cranial Nerve 1 and function
Olfactory; smell
Cranial nerve 5 and function
Trigeminal; Sensation of the face, teeth and tongue, movement of jaw and chewing muscles
Cranial nerve 7 and function
Facial; taste buds at front of tongue, secretion of saliva and tears
Cranial nerve 8 and function
Vestibulocochlear; Hearing, balance, posture
Cranial nerve 9
Glossopharyngeal; taste bud in the back, swallowing, secretion of saliva
Cranial nerve 10 and function
Vagus; visceral sensation and movement
Cranial nerve 11
Accessory; swallowing and head and neck movements
Cranial nerve 12
Speech and swallowing
Forms the letter H at the center of the spinal cord
Gray matter
Composed of neuron cell bodies
Gray matter
All ascending nerves are _____ and all descending nerves are _____.
sensory, motor
Anterior tract conducts
touch and pressure
Posterior tract conducts
pain and temperature
8-12 waves per second
Alpha
12-25 waves per second
Beta
5-8 waves per second
Theta
1-5 waves per second
Delta
Cessation of brain waves
Brain death
Unresponsive, flat EEG for 10 minutes, absence of CNS reflexes, absence of non-spontaneous unassisted repiration
Brain Death
A slightly alkaline solution containing more Na, Cl, and Mg than blood plasma and less of Ca, K, and COH
CSF
Produces CSF
Chorochoid Plexus
Pathway of flow of CSF
Lateral Ventricles > Interventricular Foramen > 3rd Ventricle > Cerebral Aqueduct > 4th Ventricle > Subarachnoid Space > Reabsorption at the Arachnoid villi
Main function of CSF
Cushion the brain
Cause by excessive production of or blocked flow of CSF
Hydrocephalus
Withdrawal of CSF from the subarachnoid space
Lumbar Puncture
2 reason for a lumbar puncture
CSF is used to check for infection to identify the organism and determine the correct drug that will fight it and cross the BBB, and to check for clots or RBC rupture in the brain
Obstruction of CSF flow and aqueduct stenosis
Noncommunicating
Increase CSF secretion and secreting tumor
Communicating
Waves that occur during rest
Alpha
Waves that occur during nonREM
Delta
3 types of muscles that are controls by the autonomic nervous system
Cardiac, Smooth, Visceral
2 divisions of the autonomic nervous system
Sympathetic, Parasympathetic
Main neurotransmitter of the sympathetic nervous system
NE
Main neurotransmitter of the parasympathetic nervous system
ACh
Has long preganglionic neuron and short postganglionic neuron
Parasympathetic
Has short preganglionic neuron and long postganglionic neuron
Sympathetic
Origin of the sympathetic nervous system
Thoracolumbar (T1-T12 and L1 to L3)
Origination of parasympathetic nervous system
Craniosacral (3,7,9,10)
Receptor located at the ganglia of the sympathetic and parasympthetic nervous systems
Nicotinic
Receptor located at the effector organ in the parasympathetic nervous system
Muscarinic
Receptor located at the effector organ of the sympathetic nervous system
Alpha 1, Beta 1, Beta 2
The most common type of muscarinic receptor antagonist
Atropine
4 muscarinic receptor stimulants
ACh, Carbachol, Methacholine, Bethanechol
Catecholamines releases from the Adrenal gland
80% Epinephrine, 20% NE
Located in the smooth muscle, cause vasoconstriction, etc.
Alpha 1 receptors
Located in the heart, causes increase rate and force of contraction
Beta 1 receptors
Located in the smooth muscle, causes vasodilation of lungs, etc.
Beta 2 receptors
Cause vasoconstriction, are used as decongestants
Alpha receptor stimulators
Are used to lower blood pressure
Alpha receptor blockers
Used to stimulate the heart and cause bronchodilation
Beta receptor stimulators
Are used to slow the heart
Beta blockers
Sensors dealing with touch, deep pressure, hearing, etc. Detect mechanical deformation or the receptor or cells near the receptor
Mechanoreceptors
Detect change in temperature, stimulated by changes in metabolic rate
Thermoreceptors
Pain receptors, detect damage to tissue
Nociceptors
Detect light on the retina of the eye
Photoreceptors
Detect taste in mouth, smell, and O2 and CO2 levels in the blood
Chemoreceptors
Sensors that do not adapt at all or very slowly
Tonic
Sensors that adapt rapidly, usually no longer responding to a maintained stimulus
Phasic
Pain that is localized on the surface of the body
Cutaneous
Pain from muscles, tendons, and joints
Deep
Pain from organs, poorly localized
Visceral
In response to pain, exercise, or stress, the body releases ____ and ______
Endorphins, Enkaphalins
Pain that deals with embryonic origin and crossover of 1st and 2nd order neuorons
Referred Pain
Uncontrolled discharge of activity my neurons in the brain
Epilespy
A single motor neuron and muscle fibers it innervates
Motor Unit
The space between the nerve and the muscle membrane
Myoneural junction
Muscle cells are elongated, lack striations, are under involuntary control, and have one nucleus which is located at the center of each cell
Smooth Muscle
Muscle fibers that have cross-striations and one centrally located nucleus, and are under involuntary control
Cardiac Muscle
Muscle cell fibers are elongated, multinucleate, under voluntary control, have well-develope striations
Skeletal Muscle
From Z-line to Z-line
Sarcomere
Many small, round parallel bundles
Myofibrils
Thin filaments
Actin
Thick filaments
Myosin
Actin that is in clumps
G-actin
Actin that is in a double spherical chain
F-actin
ATP binds to _____ causing detachment of the Ca++
HMM
Binds up to 43 Ca++ within the sarcoplasmic reticulum
Calsequestrin
ATP is necessary for the
cross bridging
3 phases of the muscle twitch
Latent period, contraction period, and relaxation period
Muscle contracts but doesn't lengthen or shorten
Isometric
Muscle shortens while the load on the muscle remains constant
Isotonic
Causes of muscle fatigue
ATP depletion, COH depletion, Lactic Acid build up
Reason why cardiac muscle cells cannot undergo tetanus
They have long absolute and relative refractory periods.