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38 Cards in this Set
- Front
- Back
Most pts with PUD are what sex?
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male
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Duodenal ulcers are how many more times more common than gastric ulcers?
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3x
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For PUD, elimination of what reduces reoccurrence by half?
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H. Pylori
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In pts w/out H.plyori what is the MCC of PUD?
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NSAIDS
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What are involved in 50% of perforated ulcers?
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NSAIDS
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What is Zollenger-Ellison syndrome?
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neuro-endocrine pancreatic tumore that secretes excessive gastrin which stimulates stocmach to produce excessive acid leading to ulcers
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Dx/Dx for PUD
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-GERD
-Pancreatitis -Crohn's -gastritis -cholelithiasis/cystitis -gastric CA -CAD/Angina -hiatal hernia |
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Pts with PUD often get what type of epigastric pain?
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gnawing
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Pain with PUD is often worse when?
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at night or on an empty stomach
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Pain with PUD is often relieved with what?
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food and antacids
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Most pts with PUD are what sex?
|
male
|
|
Duodenal ulcers are how many more times more common than gastric ulcers?
|
3x
|
|
For PUD, elimination of what reduces reoccurrence by half?
|
H. Pylori
|
|
In pts w/out H.plyori what is the MCC of PUD?
|
NSAIDS
|
|
What are involved in 50% of perforated ulcers?
|
NSAIDS
|
|
What is Zollenger-Ellison syndrome?
|
neuro-endocrine pancreatic tumore that secretes excessive gastrin which stimulates stocmach to produce excessive acid leading to ulcers
|
|
Dx/Dx for PUD
|
-GERD
-Pancreatitis -Crohn's -gastritis -cholelithiasis/cystitis -gastric CA -CAD/Angina -hiatal hernia |
|
Pts with PUD often get what type of epigastric pain?
|
gnawing
|
|
Pain with PUD is often worse when?
|
at night or on an empty stomach
|
|
Pain with PUD is often relieved with what?
|
food and antacids
|
|
What are some other S/S for PUD?
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-bloating
-belching -heartburn -decreased appetite or intolerance of provacative foods -epigastric tenderness to palpation |
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What are some things that suggest a bleeding ulcer?
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-coffee ground emesis
-melana -anemia -OH |
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What are some things that suggest acute abdomen disease?
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-intense generalized diffuse abdominal pain
-rigidity -rebound tenderness -worse with movement -fever |
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What are some alarming symptoms when you inspect for PUD?
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-anemia
-weight loss -hematemesis -persistent pain -melena -heme positive stool -peritoneal signs -vomiting of partially digested foods |
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In a younger pt with no alarm symptoms, what labs to you do?
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test for H.pylori and treat
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If a person is >55 with alarm symptoms who fails empiric therapy for PUD, what shoud you do?
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EGD
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What is a qualitative and quantitative test for H.Pylori?
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-finger stick
-ELISA |
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What are some other tests you can do to check for H.pylori?
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-urea breath test
-stool antigen -histological testing with endoscopy biopsy sample |
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For tx of PUD you want to pt to stop what?
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-NSAIDS
-alcohol -coffee -cigarettes |
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If a pts test positive for H.pylori you must you what?
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triple therapy
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What are some triple therapy options for the tx of PUD?
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you need 2 abx plus an acid suppressor for 2 weeks
-Amox 1000mg BID plus clarithromycin 500 mg BID plus Lansoprazole 30 mg BID -Metroniadazole 250mg QID plus Tetracycline 500mg QID plus Bismuth subsalicylate 525mg QID plus Ranitidine 150 mg BID |
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For PUD, the PPI is usally continued for how long?
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4 weeks
|
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What works better, PPI or H2 blocker?
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PPI
|
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What is the tx for PUD if H.pylori is negative?
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-PPI for 4 weeks
-H2 blocer for 4 weeks -sulcralfate for 4 weeks |
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What is the tx for PUD if pts has evidence of GI bleeding and is hemodynamically stable?
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-IV PPI
-test for H.plyori -perform EGD |
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What is the tx for PUD if pt has evidence of GI bleeding and is not hemodynamically stable?
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-O2, IV, monitor
-fluid resuscitation w/NS or PRBC -urgent EGD with ligation -epi or sclerosing agent |
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What are some sequella to PUD?
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-bleeding
-OH -anemia -weight loss -bastric outlet obstruction -perforation leading to peritonitis |
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What are some Pearls/Pitfalls of PUD?
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-most ulcers are caused by H.plyori or NDSAIDS
-spicy food do NOT cause ulcers -acohol, coffee, cigarettes contribute to ulcers -be alert for alarm symptoms -be aware of high risk pts -always test for H.pylori |