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15 Cards in this Set
- Front
- Back
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BB CI
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symptomatice bradycardia
> or + second degree heart block ( in absence of a pacemaker) SBP<85 severe asthma decompensated HF |
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SE of BB
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Fatigue
bradycardia decreased exercise intolerance |
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MOA of BB (HF)
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inhibts the effects of catecholamines on the heart by decreasing the SNS and increases EF
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Advantages BB in HF
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decrease CV mortality
increase EF generic and inexpensive |
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Disadvantages of BB in HF
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doses have to titrated over weeks to target doses to provide CV benefits
patient will feel teriible during the intitataion of BB therapy (3 months) abrupt discontinuation may worsen HF |
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monitoring for BB
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BP
HR S/Sx of HF weight |
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Digoxin CI
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> or = 2nd degree hreat block (inabscence of a pacemaker)
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Dig SE
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bardycardia/heart block
DIg toxicity (visual distribancs, N/V, confusion) |
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Dig advantages in HF
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improves symptoms
decreases hospitalizations improves QOL |
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dig disadvantages in HF
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abrupt discontinuation may worsen HF
must monitor serum levels (0.5-1 ng/mL) no effect on mortality |
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Dig monitoring
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HR
serum concentrations (0.5-1ng/ML) electrolytes (hypo K, Hypo Mg, Hyper Ca) |
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ACE SE
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Hyperkalemia
cough angioedema |
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ARB SE
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hyperkalemia
angioedmea decrease renal function |
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ACE MOA
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blocks the conversion of angiotensin I to angiotensin II causing vasodilation
also inhibits the breakdown of bradykinin |
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Dig MOA
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inhibits the Na/K atpase pump increaseing intracellular CA and therefore increasing contractiliy and it also decreases neurohormanal activation
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