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18 Cards in this Set

  • Front
  • Back
Corticosteriods Overview?
-produce at adrenal cortex
-affects almost all body organs
-plays a major role in maintaining hemeostasis
-Hypothalamus controls secretion (anterior pituritary & adrenal cortex)
Glucocorticoids overview?
-include cortisol, corticosterone, cortisone
-Cortisol 95 % activity
-Secreted cyclically (largest amount in AM, least amount PM
Mineralcorticoids overview?
-Maintain fluid and electrolyte balance
through salt & water metabolism

- Aldosterone major mineralcorticoid

- Adrenal Sex Hormones
Corticosteriods Indications & Usage?

# 1
1. Adrenal insufficiency (Long term Replacement)
a. give am or divide 2/3 in am and 1/3 PM
b. increase during stress (illness,trauma, surgery, etc)
c. wear medical alert bracelet
d. Monitor closely for adverse effects
Corticosteriods Indications & Usage?

# 2,3,4
2. Allergic disorder:
hypersensitivity disorders - allergic reactions to drugs, blood transfusions

3. Collagen disorders
-SLE, Scleroderma

4. Dermatologic disorders
-Acute contact dermatitis, hepers zoster, skin rashes, Erythema multiforme
Corticosteriods Indications & Usage?

# 5,6,7,8
5. Gastrointestinal Disorders
-ulcerative colitis, chohn's disease

6. Hematologic disorders
-ITP, hemolytic anemia

7. Hepatic disorders
-cirrhosis

8 Neoplastic Disease
-ALL, CLL, Hodgkin's, Lymphona, Multiple Myeloma
Corticosteriods Indications & Usage?

# 9,10,11,12
9. Neurologic Conditions
-Cerebral Edema, Brain tumors, Myasthenia gravis, acute spinal cord injury

10. Opthalmic disorders:
-Optic neuritis, Sympathetic opthalmia

11. Renal disorders
-nephrotic syndrome

12. Respiratory disorders?
- Asthma, COPD, Rhinitis, Status asthmaticus
Corticosteriods Indications & Usage?

# 13,14,15
13. Rheumatic disorders
-RA, Osteoarthritis, Bursitis, Gouty arthritis,

14. Addisonian crisis

15. Suppression of immune response to organ & tissue transplants & grafts
Corticosteriods Short term Usage?
1. acute exacerbations & to adjunct other therapies

2. When acute give IV, switch to PO

MUST GRADUALLY WEAN
D/C EARLY
Corticosteriods Contraindications?

3
1. systemic fungal infection

2. hypersensativity of drug

3. Use cautiously with pt with infections, diabetes, peptic ulcer disease, IBD, HTN, CHF & renal insufficiency
Corticosteriods

NURSING INTERVENTIONS

# 1- 4
1. Protect Pt from infection
(aseptic technique, handwashing, dressing changes, limit exposure with sick people, protective isolation if necessary, MONITOR WBC, TEMP)

2. Encourage activity
(ROM, Walking, turn and positioning Q2h)

3. Monitor BS Q6H

4. Monitor Vitals Signs (BP)
Corticosteriods

NURSING INTERVENTIONS

# 5-8
5. Monitor Edema & Weight gain

6. Monitor daily electrolytes (K, NA, cardiac arrythmias)

7. Monitor Dietary Intake
Low Na, High K, high protein diet, calcium & vitamin D supplements

8 Meds to treat/ prevent side effects (PPI, insulin)
Corticosteriods

NURSING INTERVENTIONS

# 9-13
9. Monitor psychological status
10. Monitor eye for cateracts or glucoma
11. Avoid stressful situations
12. Avoid fatigue
14. Patient Education
ADVERSE REACTIONS (I.E)
-insomnia
-increase NA and H20 retention
-Increase K excretion
-Supressed immune and inflammatory response
- osteoporosis
-intestinal perforation
-peptic ulcers
-impaired wound healing
ENDOCRINE SYSTEM REACTIONS (I.E)
- DM
-Hyperlipidemia
-adrenal atrophy
- Cushingoid signs and symptoms (such as buffalo humps, moon face, and elevated blood glucose levels).
NURSING INTERVENTIONS (I.E)
-Baseline BP, Fluid & Electrolytes & weight, Reassess regularly

- Depression (high doses)

- Glucose

- Stress levels
KEY NURSING DX (I.E)
-Risk for infection r/t immunosuppression
-Excess fluid volume
-Disturbed body image
-imbalanced nutrition; more than body requirements
-imbalanced nutrition; less than body requirements

- Risk for injury, impaired skin integrity,

- ineffective coping

- knowledge decifit
ABRUPT WITHDRAWAL (I.E)
-Rebound inflammation
-fatigue, weakness
-fever
-dizziness
-lethargy
-depression
-fainting
-orthostatic hypotension
-dyspnea
-anorexia
-hypoglycemia

-ACUTE ADRENAL INSUFFICIENCY

CAN BE FATAL