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9 Cards in this Set

  • Front
  • Back
List 7 primary risk factors for CAD?
Age
FH of early CAD
Smoking
HTN
Male gender
Elevated LDL
DM
How do you calculate LDL and what do the levels mean?
LDL= Total Chol -HDL -1/5 Triglycerides
>160 = high risk
130-159 = borderline high
101-129 okay
<100 higly desirable
May be falsely low 2 months after and MI or cardiac surgery
What effect to statins have on plaque architecture?
Plaque stabilizaion
Criteria for CABG vs PCI
CABG improves survival and sx in Left Main dz and 3 vessel dz with LV dysfunction (EF <50%) CABG improves sx of angina in 1-2 vessel dz but does NOT affect survival
PCI suitable for multivessel CAD with amenable anatomy, nml LV function without DM
What pt group should definetly get PCI?
multivessel dz
nml LV function
no DM
suitable anatomy
What increses/decreases HDL?
Increase - Exercise, estrogen, small mts of ETOH
Decrease - smokinng, androgens
What are the graft survival rates?
saphenous vein 70% occlusion in 10 yrs
Internal mammary 90% patency at 10 yrs
what is the impact of balloon angioplasty on survival, stenosis patency rates, complication rates
No impact on survival proved
35-55% symptomatic restenosis within 6 months. If still open at 1 yr 65% will remain open at 5 yrs.
1% mortality, 2% MI, 3% emergent CABG (this is decreasing)
Where & how does restenosis occur after balloon angioplasty?
At the plaque fracture site thombosis is initiated leading to intiamal hyperplasia, and media smooth muscle proliferation & finally a fibrotic buldge.