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28 Cards in this Set

  • Front
  • Back

Coronary Artery Disease

occurs with artheroscleorisis


where fatty plaque deposits from in the arterial walls


- not a specific disease but a syndrome

Myocardial Infarction

Occurs with blood flow through the coronary arteries to the myocardium is completely blocked


- irritating one side of the heart leading to stretching, overworking the heart

Ischemia

A blockage in any of the coronary arteries that leads to an area of the heart dying and becoming necrotic



Traditional risk factors for Coronary Heart Disease

Unmodifiable - age, gender, ethnicity, race


Modifiable - lifestyle choices

Non-traditional risk factors for Coronary Heart Disease

C-reactive protein - means that you are at risk for developing blood clots (von Willebrand factor concentration)


Hypehomocysteinemia - genetic disorder with a lack of enzyme that breaks down homocysteine (high levels of homocysteine leads to heart attack)

Artherosclerosis

considered to be an endothelial injury


- fatty streak


- fibrous plaque builds up and narrows the lumen of vessels


- Thrombus formation that breaks apart and causes ischemia/infarction

Types of Angina (3)

1. Stable Angina


2. Unstable Angina


3. Prinzmetal Angina

Stable Angina

Occurs by physical exertion or stress


- Subsides after 15 minutes


- Chronic


- Commonly intense and commonly in men


- Blood goes to the STOMACH and not the HEART

Unstable Angina

Considered to be early stage of progressive CAD


- pain increases in severity and frequency


- may occur even when patient is at rest


- aka crescendo angina

Prinzmetal Angina

- aka vasospatic angina


- smooth muscle spazzes out in the artherosclerotic coronary arteries


- occurs at rest and without a cause


- usually occurs at the same time of day (routine)

Which drugs are good for prinzmetal angina? (vasospatic angina)

Calcium channel blockers!

Acute Coronary Syndrome (ACS)

sudden obstruction of coronary blood flow


O2 demands > O2 supply

What are women symptoms?

Women have back pain, flu-like symptoms, vomiting, shortness of breath

What are men symptoms?

Men have chest pain, angina, flu-like symptoms, vomiting, shortness of breath

Why is time so important for myocardial infarctions?

Once the blood is blocked in the heart for longer than 20 minutes, the effects (cellular death and tissue necrosis) are irreversible


- TIME IS MUSCLE

What are the results of myocardial infarctions?

Scar tissue forms, loss of contractibility, changes in cardiac pressure and volume


- dysrhythmias and congestive heart failure

What drugs do you use for angina?

1. Nitrates and Nitrites


2. Calcium Channel Blockers


3. Beta blockers

Nitrates/Nitrites

Relaxes smooth muscle/dilates coronary arteries


- brings O2 to heart by dilating arteries


- affects PRELOAD by reducing venous return


- used for prevention of angina

Types of nitrates/nitrites

Sublingual, tablets, capsules, IV solutions, transdermal patches, ointments, translingual sprays


- includes rapid-acting and long-lasting

Rapid-acting forms of nitrites/nitrates

are used for acute angina

- sublingual tablets, IVs

Long-acting forms

used for PREVENTING anginal episodes

Nitroglycerin

In oral form, they bypass the first-pass effect


- for symptomatic treatments


- IV for BP control, treatment of CHF, ischemic pain, pulmonary edema

Adverse affects for Nitrates/Nitrites

headaches (most common)


- reflex tachycardia (rebound tachycardia)


- postural hypotension


- Tolerance may develop

Patients should report..

Blurred vision, persistent headaches, dry mouth, edema, fainting episodes, weight gain, dyspnea

Instruct your patients to avoid...

- Alcohol


- Changing positions too quickly


- Hot baths/whirlpools

Why shouldn't you expose Nitrates to light?

Chemical changes in the medication!

What to teach patients using Beta Blockers?

Monitor for pulse less than 60 beats.


- Do not stop medications quickly.


- Long-term prevention

What to teach patients using Calcium Channel Blockers?

Constipation is a common problem!


- Tell them to eat high in fiber foods