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33 Cards in this Set
- Front
- Back
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MoA of acetylcholine
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non-selective muscarinic R agonist
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MoA of adenosine
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non-selective adenosine R agonist
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MoA of albuterol
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selective beta-2 R agonist, inhaled
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MoA of aminophylline (theophylline ethylenediamine)
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adenosine antag, PDE inhibitor, IV
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MoA of beclomethasone dipropionate
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glucocorticoid pro-drug, inhaled
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MoA of disodium cromoglycate (cromolyn sodium)
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mast cell stabilizer, inhaled
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MoA of epinephrine
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non-selective adrenoceptor agonist
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MoA of fluticasone
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glucocorticoid, inhaled
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MoA of histamine
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non-selective histamine R agonist
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MoA of ipratropium
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selective M3 antagonist, inhaled powder
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MoA of isoproterenol
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non-selective beta R agonist
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MoA of leukotrienes (several)
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multiple leukotriene R agonists
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MoA of magnesium sulfate
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cell membrane stabilizer, IV - simple, effective in acute asthma
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MoA of montelukast
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LTD-4 R antagonist
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MoA of nedocromil
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mast cell stabilizer, inhaled
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MoA of omalizumab
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humanized IgE antibody, for chronic severe non-controlled disease
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MoA of prednisone
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glucocorticoid, various routes
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MoA of salmeterol
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long-acting beta-2 R agonist (+), slow onset, not for acute asthma
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MoA of terbutaline
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selective beta-2 R agonist
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MoA of theophylline
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adenosine antag, PDE inhibitor, oral
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MoA of tiotropium
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selective M3 antagonist, long acting, inhaled powder
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MoA of zafirlukast
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LTD-4 R antagonist, once daily dosage
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MoA of zileuton
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5-lipoxygenase inhibitor
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active placebo
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provides an internal cue that active medication has been taken
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nocebo
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a non-specific treatment that produces an adverse effect
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placebo
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the biology of belief, hope, empathic communicationbetween healer and patient, etc.
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What are the limitations of cromolyn?
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less potent than steroids
may produce coughing during inhalation |
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What are the SE of inhaled steroids?
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low doses: candidiasis
high doses: growth retardation & other systemic effects |
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What are the SE of oral steroids?
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high doses: GI problems & CNS disturbances
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What are the SE of leukotriene antagonists?
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rare hepatotoxicity & eosinophilia
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What are the limitations & SE of theophylline?
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narrow therapeutic index
nausea & vomiting seisures cardiac dysrhythmias |
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What are the limitations of beta-adrenergic receptor agonists?
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tachycardia
tremors |
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What are the SE of anti-muscarinic drugs?
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dry mouth
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