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9 Cards in this Set
- Front
- Back
40 year old with a family history of lung disease presents with difficutly breathing. Genetic testing shows a PiZZ phenotype. There are high levels of elastase in the lung and low levels of alpha 1 antitrypsin. His lungs show enlargement and destruction of all structures distal to the terminal bronchi (acinus). Bullae are present. What is the diagnosis?
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Panacinar Emphysema
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50 year old heavy smoker presents with difficuty breathing. There are high levels of elastase in the lung and low levels of alpha 1 antitrypsin. His lungs show enlargement and destruction of respiratory bronchioles (proximal to alveoli) especially in the upper lobes of the lung. What is the diagnosis?
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centriacinar emphysema
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18 year old college freshman was tackled in a football game and suddenly could not breath. . There are high levels of elastase in the lung and low levels of alpha 1 antitrypsin. His lungs show enlargement and destruction of distal alveoli. What is the diagnosis?
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paraseptal emphysema
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50 year old male smoker presents who lives in a Latvia (cold) next to a power plant (pollutants) presents with a 3 year history of coughing up sputum which has been present on most days for the last 3 months. Analasis of his bronchii and small airways shows an increase in size and number of goblet cells and mucus producing glands in the epithelial lining. INFLAMMATION & fibrosis of the bronchii & small airways are also present. Lately he has developed complications of lung congestion & right ventricular hypertrophy. His sputum cultures out bacteria. What is the diagnosis?
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Chronic bronchitis
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Lungs were examined on a 16 year old who was killed in an LA (environmental pollutants) shooting. Examination shows inflammation of the bronchioles.
Besides pollutants what could cause the inflammation. |
CHRONIC BRONCHIOLITIS
Viral infection |
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A 20-year-old female with a history of exzema & allergies and high IgE levels in the blood had sudden onset of wheezing with shortness of breath after exposure to ragweed. She had a history of similar previous episodes and a family history. Despite emergency treatment, she died the same day. On autopsy her lungs show mucus plugs (Curschmanns spirals) with a PREDOMINANCE OF EOSINOPHILS with Charcot Leyden crystals derived from plasma membrane of the eosinophil, CD4+ lymphocytes, aggregates of columnar cells (Creole bodies), and sloughed ciliated cells. There is also a THICKENING of airway BASEMENT MEMBRANE. What is the diagnosis?
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BRONCHIAL ASTHMA
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12 year old developes necrotizing pneumonitis after aspirating a peanut. He has foul smelling sputum & dilation of bronchial tree PROXIMAL to terminal bronchioles. What is the diagnosis? What are possible other causes for this disease
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BRONCHIECTASIS
Tumor or cytic fibrosis |
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What lymphocyte type is associated with asthma
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CD4+
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What lymphocyte type is associated with COPD
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CD8+
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