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115 Cards in this Set

  • Front
  • Back

Hindgut Fermenters

cecum

Foregut fermenters

rumen, cows,goats,sheep,giraffes,buffalo,llamas,elk

rumen sequence

1.Anaerobic cellulose digestion


2. Goes to Omasum and is concentrated by water adsorption


3.goes to abomasum, true stomach. acid kills and digests food and microbes


4. digested food go to small intestine

rumen products

Cellulose into volatile fatty acids, co2, ch4


57.5 glucose->65 acetate, 20 propionate, 15 butyrate

benefits of microorganisms in gut

vitamin synthesis


glycosidase activity


steroid metabolism


simulation of immune system


antagonism of pathogens

Obese people have higher numbers of

Firmicutes

changes in microbial community

dysbiosys


Heritable symbionts that live inside host cells

Bacterioictyes

Buchnera Bacteria

Pea Aphids

Wolbachia Bacteria

parasitic symbiont

Lower termites

acetate

aliivibrio fischeri

bacteria in squid that glows

trophosome

spongy cells in sea worms where bacteria live

Lactoperoxidase

in saliva, kills bacteria by toxic oxygen product



Lysozyme

in saliva, enzyme that cleaves peptidoglycan

Helicobacter pylori

colonizes stomaches, associated with stomach ulcers

Lactobacillus acidophilus

ferment glycogen to acid in pussy to make it acidic

tropism

ability for pathogens to detect specific tissues and sites for binding

Clycocalyx

polymers surrounding bacteria that help in biofilm formation. Slime layers, capsules

phagocytes

cells that detect and eat pathogens

adaptive immunity

1.recognize


2.discriminate


3eliminate

Lymphocytes

responsible for adaptive immunity. activated and programmed

Antigen

molecule or portion of molecule that stimulates immune system response

macrophages

usual phagocyte

present

when a macrophage projects pieces of pathogen

T cells

process presented antigens from macrophages

Tc cytotoxic cells

kill infected cells

Th helper cells

release cytokines that induce inflimation


stimulate antigen reactive b cells to proliferate and produce antibodies

B cells

recognize antigen, present to t cell. b cell produces antibodies.



plasma cells

search and destroy pathogens

memory b cells

cells ready to alert presence of preexisting pathogen

epitopes

sites that are recognized by cells

superantigens

bacterial exotoxins that cause excessive immune response

toxoid

exotoxins that have been chemically deactived but still antigenic

inactivated pathogen

killed virus or bacteria

live attenuated pathogen

mutated variant, doesnt cause disease but stimulates immune system

Urine

bacteriuria

blood

bacteremia,

Purlent discharge

pussy discharge

serology

use of antigen antibody reactions to detect, antigens, or antibodies in patient.

Mantoux skin test

tests for tuberculosis

agglutination

binding of antibodies to large cell to visualize

Protein A

found on the surface of Staphylococcus aureus cells

5 methods of antibiotics

critical biochemical pathway


dna/rna synthesis


cell wall synthesis


inhibtion of translation


altering cell membranes



Sulfanilamide


Isoniazid

blocks creation of nucleic acids

Quinolones

DNA gyrase inhibitors, blocks DNA replication

Penicillin G

beta-lactam, stopping transpeptidase bonding

cephalosporins

inhibit peptidoglycan synthesis

Kanamycin, erythromycin, tetracyclines

bind to ribosomal subunit to stop translation

Daptomycin, ionophore

puts holes in cell wall

Methicillin resistant Staphylococcus aureus

MRSA, skin pathogen,

Vancomycin resistant Enterococcus

VRE, occur in hospitals

Class A

Bacteria, anthrax, botulism, plague, tularemia


Virus, smallpox, viral hemorrhagic fevers

Anthrax

Bacillus anthracis, spores germinate to cause infection, 3 types of infection

Smallpox

Variola major. aerosol transmission.


Pustules, septic shock, toxemia

Cholera

Vibrio cholerae, waterborn bacteria

Carbapenem resistant enterobacteriaceae

Escherichia coli


Klebsiella pneumoniae






new delhi metallo beta lactamase


klebsiella pneumoniea carbapenemase

Methicillin resistant staphylooccus aureus

MRSA. resistant to beta latam methicillin

Streptococcus pyogenes

Group A strep


upper respiratory tract


causes streptococcal pharyngitis


beta hemolysis

Scarlet fever

caused by continuation of group a Strep


erythrogenic exotoxin, beta hemolysis

Rheumatic Fever

Group A strep syndrome,


patients immune system attacks heart, kidney, joints

Necrotizing fasciitis

invasive strep A infection. Exotoxins and mprotein act as superantigens.

Group B strep

newborn babies, old, pregnant,


Streptococcus agalactiae



Streptococcus pneumoniae

Pneumonia, invasive lung infection


Bacterial meningitis (inflamation of spinal coat)



Diptheria

Corynebacterium diptheriae


infects upper respiratory tract


causes lesions called pseudomembrane


some cause diptheria toxins that inhibit protein synthesis

Pertussus

Whooping cough


Bordetella pertussis


filamentous hemagglutinin helps attach to upper respiratory tract


Produces pertussis exotoxin which causes cyclic amp synthesis.

Tuberculosis

Mycobacterium tuberculosis


intracellular paracite that attacks immune cells


hyperimmune response creates tubercules


two antibiotic forms MDR XDR



Leprosy

Hansens Disease


Mycobacterium leprae


bacteria invade macrophages


produces lesions

Bacterial meningitis

Neisseria meningitiidis


several things cause menningitis


bacteremia to septicemia



Measles

Rubeola virus


infects respiratory tract, fever rash



Mumps

mumps virus, inflammation of salivary glands



rubella

german measles, rubella virus



Chickenpox and shingles

varicella zoster virus, highly contageous



common cold

rhinovirus, coronavirus


causes rhinits, inflamation of nasal membrane



influenza

single stranded rna


AB C types


A type is H or N subtype



Neuraminidase

flu subtype related to releasing from host cell

Hemagglutinin

flu subtype involded in attaching to host cells

virus naming order

Virus type/location/strain#/year/subtypes


A/hongkong/1/89/h3n4



asian bird flue

h5n1 influenza virus



Staphylococcus aureus

Abscess


impetigo (outerskin infection)


bacteremia/septicemia


wound infections


otidis media


pyogenic

Staphylococcus aureus virulence factors

hemolysis


coagulase


Leukocidin


toxic shock

Gastric Ulcers

heliobacter pylori



Hepatitis

inflamation of liver, usually caused by a virus


Hep A-E


Hep A is food


rest are diseases

Hepatitis B

HBV serum hepatitis


cirrhosis of liver


vaccine

Hepatitis C

blood body fluid


no vaccine

Gonorrhea

Neisseria gonnorrhoeae

Syphilis

Treponema pallidum


no reinfection


forms chancre


disseminates


gets you good

Chlamydia

Chlamydia trachomatis


obligate intracellular parasite


most prevalent STD


Obligate intracellular parasite


Elementary>cell and works>elementary


Chlamydial non gonococcal urethritis

herpes

herpesvirus


HSV1 Cold sores


HSV2 Genital sores



Human papillomavirus

causes cancers, cervix

AIDS

Human immunodeficiancy virus


targets immune cells with CD4 and CCR5 proteins, gp120 likes them.


C.O.D is opprotunistic pathogens


Pneumonia jiroveci


Candida albicans


Toxoplasma gondii



Rabies virus

attacks central nervous system, grows in brain, can be treated post exposure, produces negri bodies

Hantavirus

Hantavirus is BSL4


Hantavirus pulmonary syndrome causes edema


Hemmorrhagic fever with renal syndrome infection in kidneys

West nile virus

bird disease, kills horses


dead end hosts

Rickettsial diseases

caused by obligate intracellular parasites


Rocky mountain spotted fever


Ehrlichiosis


typhus


Q fever

Rocky mountain spotted fever

Rickettsia rickettsii



Ehrlichiosis and Anaplasomis

dogs and humans, tick transmission, infects white blood cells


Caused by Ehrlichia family

typhus

Rickettsia prowazekii


humans are only host


headlice transmission

Qfever

Coxiella burnetti, tick spread, sheep cattle


contact with urine feces milk from infected animal

Lyme Disease

Borrelia burgdorferi, spread by deer tick



Plague

Yersinia pestis


rat resivoir, flea transmission


Bubonic: lymphs


Pneumonic: lungs


Septicemic: blood

Tetanus

Clostridium tetani bacterium


spores germinate in anoxic deep wounds


results in spastic paralysis

Gas gangrene

Clostridium perfringes


inhabits soils, colonize deep wounds


bloating

Staphylococcus aureus

food poisoning


enterotoxins act as superantigens

Salmonellosis

Salmonella enterica


divided into many serotypes

Enterocolitis

caused by salmonella


colonize in intestine


enterotoxins and endotoxins kill cells



Typhoid Fever

salmonella typhi


waterborn foodborn

E. coli food infections

use diarrhea as advantage

Shiga toxin producing ecoli

Ecoli O157:H7


enterohemorrhagic e coli


bloody diarrhea

Enterotoxogenic E coli

non bloody diarrhea

Campylobacter

Campylobacter jejuni, found in poultry, most common cause of diarrheal illness

Listeriosis

Listeria monocytogenes


can grow in cold


high mortality

Norovirus

common cause of gastroenteritis

18 viral particles cause infection


outbreaks during winter

Cholera

Vibrio cholerae


waterborn, inadequate sanitaion


severe diarrhea

Legionnaires disease

Legionella pneumophila


causes pneumonia


waterborne