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4 Cards in this Set

  • Front
  • Back
What are the normal values for the following blood gas measurements?
PaO2
PaCO2
pH
BE
Bicarb
PaO2. 95-100mmHg
PaCO2. 40mmHg
pH. 7.4
BE. 0
Bicarb. 26Meq/L
How much oxygen is dissolved in the plasma per 100mL of blood compared to that bound to haemoglobin?
0.3mL oxygen per 100mL plasma
20mL oxygen per 100mL red blood cells
Describe the mechanism by which different types of chemoreceptors detect oxygen and carbon dioxide levels. Include their location and the nature of their response.
Central chemoreceptors in the medulla
Detect CO2 (highly soluble, crosses blood-brain barrier into CSF)
Produce a linear response

Peripheral chemoreceptors in the carotid body and aortic arch
Detect O2 and CO2
Produce a linear response
What are the 2 patterns of respiratory failure and how do they differ?
Hypoxic respiratory failure
Low arterial O2 with normal/low CO2. Type A ("pink puffer")

Hypercapnic respiratory failure
Low arterial O2 and high CO2. Type B ("blue bloater").
Worse with sleep: plays key role in disease progression

"Won't" breathe - pump or control problem

"Can't" breathe - lung (gas exchange) problem