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7 Cards in this Set
- Front
- Back
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4 classes of contraceptive steroids |
Estrogens Agonists for nuclear ERalpha and ERbeta Progestogens Agonists for nuclear PRalpha and PRbeta |
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Estrogens drugs |
Physiological Estradiol Estriol Synthetic Ethinylestradiol Diethylstilbestrol (DES) Mestranol |
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Agonists of nuclear ERalpha and ERbeta mode of action |
Suppress GnRH , LH , FSH Acts as mitogen Induce proliferation of breast and endometrial cells |
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Progestogen drugs |
Physiological Hydroxyprogesterone Medroxyprogesterone Dygesterone Synthetic : derivatives of Testosterone 2nd gen: norethisterone, norgestrel, ethnodiol 3rd gen: desogestrel, gestodene |
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Agonist for nuclear PRalpha and PRbeta |
Suppress GnRH , LH , FSH THICKEN cervical mucus cells Stop sperm getting into uterus Endometrial deciduation: thickening of endometrium: blocks implantation |
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Estrogen only contraceptive pills ?? |
Discontinued Caused cancer |
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COCP |
Estrogen + progestogen Ethinylestradiol + synthetic progestogen 21/28 days 7 days withdrawal bleeding |
