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75 Cards in this Set

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What are the 4 tissue classifications? ECMN

Epithelial


Connective


Muscle


Nervous

What is tissue classification based on?

It’s based on structure of cells, composition of non cellular extracellular matrix, and cell functions

What is histology of tissues? What are the 2 histology?

Microscopic study of tissues


1. Biopsy- removal of tissues for diagnostic purposes


2. Autopsy- examination of organs of a dead body to determine cause of death

What are 7 characteristics of epithelial tissue?

Predominantly cells


Creates glands


Covers body surfaces & forms glands


Avascular - means no blood supply - only by diffusion


Outside surface of the body


Lining of digestive, respiratory and urogenital systems & body cavities


Heart & blood vessels

What does the term mean basement membrane?

Extracellular- firmed by secretions of both epithelial & connective tissues


Acellular glue

What functions do the Epithelial tissue have?

Protecting- underlying structures- lining of the mouth


Acting- as barriers - skin


Permitting- the passage of substances- nephrons in kidneys


Secreting- substances- creating - pancreas glands


Absorbing - substances- lining of small intestines

What are the 2 classifications of EPITHELIUM?

1.Number of layers of cells


2. Shape of cells

What are the 3 types of layer of cells? Explain

1. Simple- one layer of cells - each extends from basement membrane to the free surface


2. Stratified- more than one layer- shape of cells of the apical layer


3. Pseudo-stratified- tissue appears to be stratified. But all cells contract basement membrane- simple - transitional

What are the 4 shapes of epithelium cells? SCCG

Squamous- flat- scale like


Cuboidal- equal in height & width


Columnar- taller than wider


Goblet- looks like a cup that is a goblet

What are the functions of the simple cells?

Allows diffusion of gases, filtration of blood. Secretion & absorption


Thin as possible

What are the functions of the stratified cell?

More than one layer


Protection, particularly against abrasions- eg. Skin

What are the functions of the Squamous cells?

Allows diffusion


Acts as filter

What are the functions of the cuboidal & columnar do?

Secretion


Absorption


May include goblet cells

What functions does a goblet cell do?

Produce mucus


Protection

What are the free surfaces of epithelial tissues?

Smooth - reduce friction


Microvilli- increase surface area for absorption or secretion


Stereocilia - elongated microvilli for sensation & absorption


Cilia- move materials across the surface

What are the functions of the simple squamous epithelium?


DFPSA

Diffusion


Filtration


Protection against friction


Secretion


Absorption

What are the locations that simple squamous epithelium is found? 2

Lining of the blood & lymphatic vessels


Alveoli of the lungs

What is the structure of simple squamous epithelium?

Single layer of flat cells

Where is simple cuboidal epithelium found?

It’s transitional


It’s only found in the lining of the urinary bladder


It’s makes & releases substances

Where is the location of the simple cuboidal epithelium?

Kidneys tubules


Glands & their ducts

What is the structure of simple cuboidal epithelium?

Single layer of cube shaped cells - some have microvilli (kidney) or cilia (bronchioles of lungs)

What is the function of the simple cuboidal epithelium?

Secretion! In glands & choroid plexus

Ok now onto simple columnar epithelium . What’s the


1. location


2. Structure


3. Function

1.glands & some ducts


2. Single layer of tall, narrow cells- cilia (bronchioles of lungs) & microvilli (intestine)


3. Secretion by glands of the stomach & the intestines


Absorption by cells of the intestines

Ok now we discuss stratified squamous epithelium. What’s the location of these?

Moist— mouth-larynx -esophagus-anus-vagina- inferior urethra& cornea


Places that are exposed to the outside world


Keratinizated- skin / structure protein & water proof -


In keratinized surface cells are dead


Layers of FAT CELLS- layers & layers

What’s the structure of simple squamous epithelium?

Multiple layers of cells that are cuboidal in the basal layer & progressively flattened towards the surface.

What is the function of the stratified squamous epithelium?

Protection against abrasions


Caustic chemicals


Water loss


Infection

Ok now stratified cuboidal epithelium. What’s the


1. Location


2. Structure


3. Function

1. Sweat gland ducts


2. Multiple layers of somewhat cube shaped cells


3. Secretion


Absorption


Protection against infection

Ok now onto stratified columnar epithelium. What’s the


1. Location


2. Structure


3. Function

1. Mammary gland ducts


2. Multiple layers of cells with tall thin cells resting on layers of more cuboidal cells (ciliated in the larynx)


3. Protection and secretion

Ok onto pseudo stratified columnar epithelium. What’s the 1. Location


2. Structure


3. Function

1. Lining of the nasal cavity. Pharynx. Trachea. Bronchi of lungs


2. All cells reach basement membrane.


Appears to be stratified b/c nuclei are at various levels


Ciliated & associated with goblet (mucus producing) cells


3. Secretes mucus onto the free surface


Move mucus/ fluid that contains foreign particles over the free surface & from passages


Interspersed with goblet cells

Ok now transitional epithelium. What’s the 1. location 2. Structure 3. Function

1. Lining of the urinary bladder


2. Stratified- cells change shape


3. Accommodates fluctuations in the volume of fluid in an organ or tube.


Protection against the caustic effects of urine

What are glands lined with?

Lined with epithelium tissue


Epithelium with supporting network of C.T.

What are glands lined with?

Lined with epithelium tissue


Epithelium with supporting network of C.T.

What are the 2 types of glands that are formed by infolding of epithelium?

1. Endocrine- makes & secretes hormones- no open contact with exterior. No ducts .


Glands in body


Stay in bloodstream


2. Exocrine- outside of ur blood stream - OPEN contact maintained with exterior - ducts


Not going into blood


Secreting something outside the body- sweat / mucus / tears /GI TRACK / mammary glands

What are exocrine glands classified as?

By structure


By the method of secretion

What is the classification of structure?

Unicellular Goblet cells - single cell (mucus)


Multicellular - simple & compound (don’t need to go in-depth)

Explain 5 things about connective tissue. AMDVfOccP?

Abundant- found in every organ


Consists of cells separated by extracellular MATRIX (framework)


Many diverse types


Performs variety of important functions


Tissues that makes organs


Lined with cuboidal & columnar


Parenchyma??

What are the functions of connective tissue ? 7

1. Enclose organs as a capsule


2. Connect tissues to one another (tendons & ligaments)


3. Support & movement (bones)


4. Storage(fat)


5. Cushion & insulation (fat)


6. Transport (blood- red & white -immune system)


7. Protect - cells of the immune system

What specialized cells does the connective tissues produce?

The extracellular MATRIX

What is blasts? In connective tissue..

Creates the matrix, builds it


Eg. Osteoblasts- make bone


Eg. Condroblasts - makes cartilage

What is the term cytes mean with connective tissues?

Maintain the matrix


Eg. Chondrocyte . Keeps the bone the way it is.


Just does the function of the cell

What does the term classy mean in connective tissue?

Break the matrix down for remodeling


Eg. Osteoclasts . Less bone

What are the 5 types of connective tissue cells? Explain each one

1. Adipose/fat cells (adipocytes) common is skin-dermis


2. White blood cells (leukocytes) respond to injury/infection- immune for protection


3. Macrophages- fixed (stay in position in CT) & wandering (move by Amoeboid movement through the CT)


4. Platelets- bone marrow - fragments of hematopoietic cells in clotting


5. Undifferentiated Mesenchyme- stem cells could turn into other specific types of cell- into adult cells

What are the 3 extracellular matrix protein fibres in CT? CRE

1. Collagen- strong, flexible, inelastic


2. Reticular - fills the spaces & doesn’t stretch


3. Elastic -returns to its original shape after distension or compression


Remember like a spring - it stretches than goes back to its shape


Note : most tissues are a mixture of all 3 types!

What is loose(Areolar) CT?

It’s the filler


Superficial fascia


Loose packaging material of most organs & tissues. Aka STROMA

What are the CT with special properties?

Adipocytes - predominant cells

What are the 2 cell types in adipocytes? explain YB

1. Yellow (white) - most abundant type , has a wide distribution. White at birth & yellow with age


2. Brown - found only in specific areas of the body, axillae, neck & near kidneys heat metabolic active


Babies done chill cause of Brown fat

Know: what are the dense regular collagenous CT ? And what are the 2 fibres that resist stretching? TL

Has abundant COLLAGEN fibres that resist stretching !


1. Tendons- connect muscles to bones, fibres are not necessarily parallel


2. Ligaments- connect Bones to bones - densely packed fibres

What are the supporting CT tissue ; Cartilage?

Chondrocytes- located in the matrix surrounded spaces called Lacunae


Type of cartilage determined by components of the matrix


Firm consistency


Avascular & no nerve supply


Heals slowly


Cell cartilage


No blood supply


No nerve supply

Types of supporting CT : cartilage? HFE

Hyaline


Fibrocartilage


Elastic

What is the Dense Irregular ELASTIC CT?

Stretches


In walls of elastic Big arteries


Strong


Bundles and sheets of collagenous & elastic fibres oriented in multiple directions

What are the Dense Irregular Collagenous CT?

Random oriented network


Outside capsule


Forms the innermost layer of the dermis of the skin, scars.


Capsule of the kidneys and spleen

What is hyaline cartilage? Smooth

Large amounts of collagen fibres evenly distributed in PROTEOGYLCAN matrix


Smooth surface in the articulation (joint)


Areas found in - ribs cage- trachea & bronchi


In embryo forms most of skeleton


Increase bone length


Bone to bone

What is fibrocartilage?

Tough


Thick collagen fibres distributed in proteoglycan matrix


Found in knee. Jaw. Between vertebrae.


Found in areas of body where a great deal of pressure is applied to joints

What are Elastic cartilage?

More elastin


Elastic and collagen fibres embeds in proteoglycans


Rigid but elastic properties


Locations: external ear & epiglottis

The supporting CT Bone . Explain

Hard connective tissues composed of living cells (osteocytes) and mineralization matrix


Living CT


GIVES STRENGTH & rigidity


Allows bones to support & protect other tissues& organs

What are the organic bone CT

Collagen fibres

What are the inorganic bone in CT?

Hydroxyapatite (ca plus po4)

What are the 2 types of CT BONE?

Spongy


Compact

Explain spongy bone?

Network


Hallow


Trabeculae of bone with spaces between - looks like sponge-


Found inside the bone

What is compact CT bone?

Arranged in concentric circle layers around a central canal that contains a blood vessel.


Looks like a tree!

What are the characteristics of muscle tissue?

Contracts/ shortens with force


Moves entire body & pumps blood

What are 3 types of muscle tissues? SCS

Skeletal


Cardiac


Smith

Define skeletal in muscle tissue??

Attached to skeleton / bone


Striated & voluntary


Conscious control of it

Define cardiac in muscle tissue..

Muscle of heart


Striated & involuntary

Define smooth in muscle tissue

Associate with tubular structures & with the skin


Lines the blood vessels


Lines the digestive track


Non striated & involuntary

Which one is voluntary?


Skeletal


Cardiac


Smooth

Skeletal

Which ones are involuntary?


Skeletal


Cardiac


Smooth

Cardiac (Striated)


Smooth (non striated)

What does the tissue membranes do?

Line surfaces and cavities


Protective membrane

What are the 3 types of tissue membranes?

Mucous


Serous


Synovial

Explain mucous? In tissue membrane

Lines cavities that open to the outside body


Secretes mucus


In the respiratory- digestive- urinary and reproductive systems

What does the tissue membranes do?

Line surfaces and cavities


Protective membrane

What are the 3 types of tissue membranes?

Mucous


Serous


Synovial

Explain mucous? In tissue membrane

Lines cavities that open to the outside body


Secretes mucus


In the respiratory- digestive- urinary and reproductive systems

Explain serous tissue membrane?

Simple squamous epithelium called mesothelium


Lines cavities not open to exterior


Pericardial - pleural - peritoneal


Thin layer of loose CT

What is the synovial tissue membrane?

Line freely movable joints


Produce fluid rich in hyaluronic acid