Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
24 Cards in this Set
- Front
- Back
|
Functions of CT
|
-structural support
-medium for exchange -defense/protection |
|
|
What's CT made of
|
-extracell matrix:
ground subst.,extracell fibers,tissue fluid -Cells |
|
|
2 types of CT
|
Loose connective/dense connective
|
|
|
LCT
|
-made of fibers=reticular/collagen/elastic
-ground subst=for H2O diffusion,O2,CO2, nutrients -lots of cells: fibroblasts/macrophage/leuko/adipose/mast |
|
|
DCT
|
-made of dense fibers
-has fibrobblasts -makes=tendons/ligaments/aponeuroses (all have coll type 1) |
|
|
Collagen
|
-most abundant
-flexible -stains pink w/ eosin dye -fiber->fibrile->collagen |
|
|
Type 1 collagen
|
in fibriles,fibers,bundles
-dentin -tendons -ligaments -bone |
|
|
Type 2
|
just fibriles
-elastic cartilage -hyaline cartilage |
|
|
Type 3
|
fibriles & reticular fibers
-lymph -spleen -organs |
|
|
Type 4
|
filaments
-BL |
|
|
Type 5
|
-placenta
|
|
|
Coll synth.
|
in RER:
preprocoll->signal cut->procoll->hydroxylation by proline & lysine residues->now its glycosylated & procol forms trip helix-> exported out of golgi->tropocoll 2 alpha,alpha & 1 alpha 2 chain |
|
|
Reticular fibers
|
-support & framework for tissues & organs
-type 3 -in nerves/bv's/muscle/lymph/rd bone marrow/endocrine glnds |
|
|
Elastic fibers
|
-elastisity
-in EC matrix -made of proteoglycans & glycoprots (rich in pro &gly) -in LCT/aorta/ligamentum flavae |
|
|
Ground Substance
|
-allows for diff of nutrients & O2
-inc H2O content made of: proteoglycans that are made from GAG,& glycoprots these form polycacc chains |
|
|
What does GAG do?
|
-sulfation of sugar residues->causes charge->allows basic dye stains->attracts H2O->hydrates gel->allows diff of H2O & sol subts
|
|
|
7 types of GAG's
|
based on degree of sulfation & type of sugar residue
-2 chondrotins -2 heparans -1 hydronic acid -1 keratin -1 dermatin |
|
|
Fibroblast cells
|
-fixed
-makes & destroys collagen,grnd subst.,elastic & retic fibers -2 forms inactive & active active= in cytoplasm,lots of it,lots of RER,irreg branched inactive= small,spindle shape,les RER |
|
|
Macrophage
|
-fixed
-from monocytes -diapedesis -have lysosomes/lots of RER/big golgi/lots of MT's & MF's function: -phago/pino -activate imm sys. -resist inf. |
|
|
Mast cell
|
-from BM
-cyto plasm has lots of granules is metachromatic release: heparin-anticoag histamine-vasodil leukotriene-slow cont of sm. musc. |
|
|
Immediate hypersensitivity rxns
|
after 1st exp. to Ag->IgE binds to its recept. on mast cell=sensitization
-after 2nd exp->same Ag binds to IgE on mast cell->degranulation->releases->histamine,leukotrines |
|
|
Plasma cells
|
make Abs to certain Ags
migrate to CT when infect. |
|
|
Mesenchyme
|
-makes lots of cells
-makes myofibroblasts for wound repair |
|
|
Adipose
|
brown-fetal gone after 10 yoa,multilocular
white-unilocular -provides energy -insulates -lots of retic fibers & bld vessels |
