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4 Cards in this Set
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CMV |
what: HHV type 5 Transmission: only 10% babies get with infected mom. Can get thru placenta, breast milk, respiratory droplets. s/s: Most asymptomatic and occurs with immunocompromised pts. Findings in infant include jaundice, hepatosplenomegaly, thrombocytopenia, perventricular CNS calcifications, mental retardation, motor disability, and purpura and can present later in life. Typical symptoms present like EBV (mono) but NO pharyngitis. dx: antigen detection in blood, urine, or CSF via PCR. Tissue biopsy reveals intracytoplasmic inclusion bodies "Owl Eyes". tx: Ganciclovir, Valganciclovir, or foscarnet. |
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Toxoplasmosis |
cause: T. gondii parasite commonly from cat litter. part of TORCH s/s: congenitally acquired see microcephaly or hydrocephaly, sever chorioretinitis, hearing loss, convulsion,s abnormal CSF, cerebral calcifications, and mental retardation. dx: serologic testing. IgG antibodies persist for life. tx: pyrimethamine for 1 yr + sulfadiazine + Leucovorin. |
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Neonatal Conjunctivitis |
Cause: Chlamydia (C. trachomatis) or Gonorrhea (N. Gonorrhoeae). transmission: vaginal delivery s/s: Neisseria causes copious purulent d/c unilaterally. Chlamydia causes mucopurulent d/c with marked follicular response on inner lids with nontender preauricular adenopathy. dx: Gram stain and Giemsa stain. C. trach- shows no organisms. Gonorrhea shows intracellular gram- negative diplococci. tx: topical sulfonamides, fluroquinolones, and aminoglycosides. |
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HIV |
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