Complete Blood Count And Differential

Front 1

hematopoeisis

Back 1

the method of red blood cell production

Front 2

what hormones control hematopoesis

Back 2

negative feed back with kidney and liver

-erythropoietin

erythropoietic factor - from the liver acting on a specific globulin - stimulates the bone marrow

Front 3

erythropoiesis what is it stimulated by (encouraged)

Back 3

stimulated in response to lowered pO2, blood loss, chronic lung disease and exercise

Front 4

erythropoiesis is decreased in people with? what to treat this with?

Back 4

kidney disease

treat with epogen

Front 5

normal range for white blood cells?

Back 5

4500 to 11,000

Front 6

normal range for red blood cells?

Back 6

man - 4.5 million to 6.1 million

Front 7

what are reticulocytes? percentage should be circulating?

Back 7

0.5 to 1.5%

if higher this means issue

Front 8

erythropoietin

Back 8

hormone that is secreted by the kidneys and liver

when falling O2 levels, then kidneys will secrete erythropoietin to increase RBC production

Front 9

what is rouleaux formation

Back 9

red blood cells are stacked like a roll of coins instead of being spread out

Front 10

what might rouleaux formation indicate

Back 10

inflammation, diabetes, immune dysfunction, infection, cancer, toxicology

Front 11

high blood cell count - why

Back 11

environmental changes

cyanotic heart disease

tumor polycythemia vera

dehydration

hemoglobinopathy - sickle cell and thalassemia

smoking

Front 12

low red blood cell count

Back 12

-pregnancy

-anemia

-hemoglobinopathy

-hemolysis

-hemorrhage

poor diet, bone marrow failure

artificial heart valves, chronic illness, rheumatoid arthritis, blood cell cancers

Front 13

what is hematocrit

Back 13

percent of blood that consists of red blood cells

Front 14

what is thalassemia

Back 14

genetic disorder where hemoglobin is made incorrectly, red blood cells thus decrease in number

Front 15

polycythemia

Back 15

increased concentration of hemoglobin in the blood

due to increased red blood cells or decrease plasma volume

Front 16

what is mean corpuscular volume?

how to calculate

Back 16

average size of the red blood cell

hematocrit x 10/RBC number

Front 17

what is mean corpuscular hemoglobin?

how to calculate

Back 17

mass of hemoglobin inside the red blood cell

hemoglobin x 100 /RBC

Front 18

mean corpuscular hemoglobin concentration

how to calculate

Back 18

percent of the red blood cell that consists of hemoglobin

can thus either be hyperchromic or hypochromic

MCHC = Hemoglobin x 100/ Hematocrit

Front 19

red blood cell distribution

Back 19

amount of variation in red blood cell size, spread out

Front 20

what is platelet count, range

Back 20

number of platelets/mm^3 of blood

150,000 to 400,000

Front 21

what is increase platelet count called

Back 21

thrombocytosis

greater than 475,000

Front 22

what is decreased platelet count called

Back 22

thrombocytopenia

enlarged spleen

Front 23

hat is mean platelet volume

Back 23

volume of platelets

- increased volume means more platelets are being made

-decreased volume means bone marrow malfunction

Front 24

granulocytes

Back 24

neutrophils

eosinophils

basophils

Front 25

agranulocytes

Back 25

lymphocytes

monocytes

Front 26

normal ranges for neutrophils

Back 26

2500 to 8000

Front 27

characteristics of neutrophils

Back 27

-stain pink

-rush to site first when acute inflammation

Front 28

what does polymorpholeukocytes mean

Back 28

multiple shaped nuclei - 2 to 5 lobes in a neutrophil

Front 29

what is neutrophilia

Back 29

elevated neutrophil count

Front 30

what is cushing's disease

Back 30

due to an adenoma in the pituitary gland

causes excess release of ACTH - which causes excess production of stress hormone cortisol