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The 4 stages of disease and their type of response

Pre-risk = disease eradication, elimination


Pre-disease =Health promotion and specific protection


Latent disease = Early pre-sympathetic diagnosis and treatment


Sympathetic disease tertiary prevention = Disability limitation for early symptomatic disease and Rehabilitation for late symptomatic disease

3 tertiary prevention of symptomatic disease are

disability, limitation and rehabilitation

Disability limitations are Disease-Impairment- Disability- Rehabilitation-Handicap

Successful prevention depends on….

-Knowledge of causation


-Dynamic of transmission


-Identification of risk factors &risk groups


-Availability of prophylactic or early detection and treatment measures

Give some reasons why prevention may not be attractive……

- Demonstration of benefits. (eg: ceasing smoking prevents lung cancer)


- Delay of benefits (eg: the effect of a “no smoking” campaign will take 20yrs to manifest)


- Accrual of benefits (eg: who benefits from program= clients, insurance company or government)

In learning the principles of diseas, epidemiology and in disease prevention there are 6 important terms name:

Pathogen


Pathology


Etiology


Infection


Disease


Host

Name the 5 stages of disease development

Incubation Period



Prodormal Period



Illness



Period of decline



Period of convalescence



[imagine the diagram]

In learning the principles of disease, epidemiology and in disease prevention there are 5 important terminology namely:

Control



Elimination of Disease



Elimination of Infection



Eradication


[exp:smallpox]



Extinction


[exp:none]

Microbs that are on or in a host, but do not cause disease. They are free germs that are found anywhere in or out the body after birth.


Some thing we live with normally can become pathogenic is …………….

Normal Flora

Types of relationships and their categorie

Commensalism (harmful)



Mutualism (helpful)



Parasitism (harmful)



Opportunism (potentially harmful )

Classifying diseases based on transmibility and give two examples each.

Communicable


Exp: cold and HIV


(Sneezing, kissing)



Non-Communicable


Exp: Cancer, asthma

Classifying diseases based on frequency of occurrence and give one example each.

Sporadic


Exp: Rabies



Endemic


Exp: Cholera



Epidemic


Exp: CSF


(Cerebrospinal Manigiatis)



Pandemic


Exp: HIV

Classifying diseases based on frequency of occurrence and give one example each.

Sporadic


Exp: Rabies



Endemic


Exp: Cholera



Epidemic


Exp: CSF


(Cerebrospinal Manigiatis)



Pandemic


Exp: HIV

Classifying diseases based on severity and give one example each.

Acute


Exp: strep throat, broken bones, appendicitis, influenza, pneumonia



Chronic


Exp: heart disease, cancer, and diabetes



Subacute


Exp: encephalitis, measles virus



Latent


Exp: Epstein-Barr virus (EBV), Varicella-Zoster virus (VZV), HIV, Herpesviruses, and Cytomegalovirus (CMV).

Classifying diseases based on frequency of occurrence and give one example each.

Sporadic


Exp: Rabies



Endemic


Exp: Cholera



Epidemic


Exp: CSF


(Cerebrospinal Manigiatis)



Pandemic


Exp: HIV

Classifying diseases based on severity and give one example each.

Acute


Exp: strep throat, broken bones, appendicitis, influenza, pneumonia



Chronic


Exp: heart disease, cancer, and diabetes



Subacute


Exp: encephalitis, measles virus



Latent


Exp: Epstein-Barr virus (EBV), Varicella-Zoster virus (VZV), HIV, Herpesviruses, and Cytomegalovirus (CMV).

Give the 3 extent of host involvement.

Primary infection



Secondary infection



Subclinical infection

Classifying diseases based on frequency of occurrence and give one example each.

Sporadic


Exp: Rabies



Endemic


Exp: Cholera



Epidemic


Exp: CSF


(Cerebrospinal Manigiatis)



Pandemic


Exp: HIV

Classifying diseases based on severity and give one example each.

Acute


Exp: strep throat, broken bones, appendicitis, influenza, pneumonia



Chronic


Exp: heart disease, cancer, and diabetes



Subacute


Exp: encephalitis, measles virus



Latent


Exp: Epstein-Barr virus (EBV), Varicella-Zoster virus (VZV), HIV, Herpesviruses, and Cytomegalovirus (CMV).

Give the 3 extent of host involvement.

Primary infection



Secondary infection



Subclinical infection

The 3 types of reservoirs of infections and mode of disease transmission are……

Humans, Animals and Non-living

Classifying diseases based on frequency of occurrence and give one example each.

Sporadic


Exp: Rabies



Endemic


Exp: Cholera



Epidemic


Exp: CSF


(Cerebrospinal Manigiatis)



Pandemic


Exp: HIV

Classifying diseases based on severity and give one example each.

Acute


Exp: strep throat, broken bones, appendicitis, influenza, pneumonia



Chronic


Exp: heart disease, cancer, and diabetes



Subacute


Exp: encephalitis, measles virus



Latent


Exp: Epstein-Barr virus (EBV), Varicella-Zoster virus (VZV), HIV, Herpesviruses, and Cytomegalovirus (CMV).

Give the 3 extent of host involvement.

Primary infection



Secondary infection



Subclinical infection

The 3 types of reservoirs of infections and mode of disease transmission are……

Humans, Animals and Non-living

The 3 main routes of reservoirs of infections and mode of disease transmission are……

Contact: Direct, Indirect, droplets exp:sneezing



Vehicle: Any mode of transmission exp: mosquitoes



Vectors: Transmission from infectious agent to any living organisms exp: flies

Routes of common methods that microbes use to exit host are……

Respiratory tract via cough, sneeze



GI tract via faeces



Urogenital via virginal/penile secretion



Skin via open wood



Blood via open woods, surgery and syringe

Routes of common methods that microbes use to exit host are……

Respiratory tract via cough, sneeze



GI tract via faeces



Urogenital via virginal/penile secretion



Skin via open wood



Blood via open woods, surgery and syringe

An infection acquired during the course of stay in a hospita, nursing home or other health facility. About 5-15%of patients acquire one. What is the name of this infection?

Nosocomial Infection

Routes of common methods that microbes use to exit host are……

Respiratory tract via cough, sneeze



GI tract via faeces



Urogenital via virginal/penile secretion



Skin via open wood



Blood via open woods, surgery and syringe

An infection acquired during the course of stay in a hospita, nursing home or other health facility. About 5-15%of patients acquire one. What is the name of this infection?

Nosocomial Infection

List the 4 preventive measures of disease and give examples.

Primordial prevention eg: eradicating of smallpox, eliminate salt from foods



Primary prevention eg: exercise, immunization, prophylaxis



Secondary prevention eg: screening



Tertiary prevention eg: physiotherapy after a stroke

Routes of common methods that microbes use to exit host are……

Respiratory tract via cough, sneeze



GI tract via faeces



Urogenital via virginal/penile secretion



Skin via open wood



Blood via open woods, surgery and syringe

An infection acquired during the course of stay in a hospita, nursing home or other health facility. About 5-15%of patients acquire one. What is the name of this infection?

Nosocomial Infection

List the 4 preventive measures of disease and give examples.

Primordial prevention eg: eradicating of smallpox, eliminate salt from foods



Primary prevention eg: exercise, immunization, prophylaxis



Secondary prevention eg: screening



Tertiary prevention eg: physiotherapy after a stroke

1. Limiting the physical and social consequences of symptomatic disease is


2. Prevention of disease before the biological onset is


1. Tertiary Prevention


2. Primary Prevention

Routes of common methods that microbes use to exit host are……

Respiratory tract via cough, sneeze



GI tract via faeces



Urogenital via virginal/penile secretion



Skin via open wood



Blood via open woods, surgery and syringe

An infection acquired during the course of stay in a hospita, nursing home or other health facility. About 5-15%of patients acquire one. What is the name of this infection?

Nosocomial Infection

List the 4 preventive measures of disease and give examples.

Primordial prevention eg: eradicating of smallpox, eliminate salt from foods



Primary prevention eg: exercise, immunization, prophylaxis



Secondary prevention eg: screening



Tertiary prevention eg: physiotherapy after a stroke

An example of CVA (cerebrovascular Accident is stroke

1. Limiting the physical and social consequences of symptomatic disease is


2. Prevention of disease before the biological onset is


1. Tertiary Prevention


2. Primary Prevention

Actions and measures that inhibit the emergence of risk factors in the form of environmental, economic, social, behavioral conditions and cultural pattern of living is

Primordial Prevention

Early asymptomatic detection and remediation of certain diseases and conditions that if left undetected would likely become clinically apparent and harmful is

Secondary Prevention


What study in which the prevalence of an exposure and/or an outcome are measured in a given population at a specified point in time?


The data may be analysed to look for an association between the exposure and the outcome.



ner



and the disease.

Cross-Sectional Study

Example: the prevalence of onchocerciasis in a particular community could be determined by a descriptive cross-sectional survey. If data on possible risk factors for onchocerciasis are collected from the same people at the same time then they could be used in an analytic study to look for associations between the risk factors and disease.

What study in which the prevalence of an exposure and/or an outcome are measured in a given population at a specified point in time?


The data may be analysed to look for an association between the exposure and the outcome.

Cross-Sectional Study

Example: the prevalence of onchocerciasis in a particular community could be determined by a descriptive cross-sectional survey. If data on possible risk factors for onchocerciasis are collected from the same people at the same time then they could be used in an analytic study to look for associations between the risk factors and disease.

What is a Case control study?

A study in which individuals with and without the outcome of interest are identified. Their status with respect to exposures of interest is then determined in order to look for associations between these exposures and the outcome of interest.

An example: we could use a case-control study to determine risk factors for diarrhoeal disease among children. We would identify children with and without diarrhoea and obtain information concerning exposures of interest (breast-feeding, water supply etc). We would then analyse the data to see if breast- feeding or water supply was associated with diarrhoea.

Cohort Study is

A study in which one or more individuals are followed up over a period to determine frequency of a particular outcome in group(s).

For example, smoking on fatal diseases was studied determining the smoking habits of large doctors, and then following them determine the causes of death. specific causes of death

A 47 year old Hungarian Physician of German Extraction known as pioneer of antiseptic procedures.


Discovered that the incidence of puerperal fever could be cut by hand disinfection.


He suggested washing with chlorinated lime solution.


He died 14 days after being committed to an asylum after being beaten by guards.


Who is this?

Semelweiss

Historical Figures of Epidemiology

Who is John Snow?

He’s 45 year old English Physician. A historical giant in Epidemiology.


He was a leader in adopting anaesthesia and medical hygiene.


He traced the source of cholera outbreak in London in 1954. He discovered that the public well had been dug only 3 feet from an old cesspit which had begun to leak fecal bacteria.

Historical Figures of Epidemiology

He’s a 76 year old British Epidemiologist.


One of the founders of Medical Statistics and was responsible for the collection of Medical Statistics. He gathered statistical evidence on people supplied with water from two companies.


Who is he?

William Farr

Historical Figures of Epidemiology

What was James Lind’s accomplishment?

Scottish Physician, pioneer of naval hygiene in the Royal navy.


"He conducted the first clinical trial, he developed the theory that citrus fruits cured scurvy.


His work advanced the practice of preventive medicine and improved nutrition. Scurvy is a disease caused by vitamin C deficiency. He recommended the benefits of citrus fruits.

Historical Figures of Epidemiology

Ancient Greek Physician and the outstanding figure in the history of medicine. He is the father of Western Medicine and credited with coining the Hippocratic Oath.


He is being credited with being the first person to believe that diseases were caused naturally and not because of superstition and gods.


He separated the disciple of medicine from religion. Priests believed that illnesses such as epilepsy was caused by gods. He is reported to have said "men believe that it is a divine disease because of ignorance and amazement".


Who is he?

Hippocrates

Historical Figures of Epidemiology