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9 Cards in this Set

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  • Back
  • 3rd side (hint)
Most important points about TDF (tenofovir) (2 answers)
Intxs w/ ddl (incr) and ATV (decr) while TDF (incr)

May cause BMD (supplement w/ Ca + D)
Interaction
SE
FTC
emtricitabine (1 answer)
Major SEs are HA and hyperpigmentation
Major SEs (2)
3TC
lamivudine (2 answers)
Intxs w/ SMX, 3TC (incr)

Major SE is insomnia
Interaction
SE
EFV
efavirenz (6 answers)
Contraind. in pregnancy
Intxs w/ buprenorphine (decr)
May cause false + for marijuana
3A4/2B6 substrate (intxs)
Major SEs (rash, dizziness, vivid dreams, incr LFTs)
Take on an empty stomach
Contraind. in ____
Intxs w/ ______
Test intx
P450 substrate for ___/___
Major SEs
Directions
NVP
nevirapine (4 answers)
Intxs w/ buprenorphine (decr)
Has a "lead-in" period
May cause fatal hepatotox (risk incr w/ CD4 <250 in men, 400 in women; not used for PEP)
Major SE of rash
Intxs w/ ____
has a ___ _____
may cause ____ _______
major SE is ___
AZT
zidovudine (2 answers)
Intxs w/ methadone (AZT decr)
Major SEs are anemia, myopathy and neutropenia
Intxs w _____
Major SEs are ___, ___, ____
ABC
abacavir (4 answers)
Major SE is hypersx
Recommended to gene test 1st
Contraind w/ mod-severe hep impairment
May cause incr LFTs
Major SE is ____
Recommended to test ____
Contraind w/ ________
May cause incr ____
All NRTIs listed on these cards need dose adj in renal insuff EXCEPT ___ which is metabolized _____
ABC
hepatically
EFV and ___ may require dose adj in hepatic insufficiency
ABC
NOT NVP