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17 Cards in this Set
- Front
- Back
What category of polyps are found in FAP - Familial adenomatous polyposis
-adenomatous -hamartomatous |
adenomatous
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What category of polyps are found in Peutz-Jeghers syndrome
-adenomatous -hamartomatous |
hamartomatous
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What category of polyps are found in Juvenile polyposis syndrome
-adenomatous -hamartomatous |
hamartomatous
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What category of polyps are found in MAP MYH-associated polyposis
-adenomatous -hamartomatous |
adenomatous
(this is the only autosomal ressive syndrome of the CRC syndromes) |
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found in Lynch Syndrome
-adenomatous -hamartomatous |
adenomatous
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found in cowden syndrome
-adenomatous -hamartomatous |
hamartomatous
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What gene is associated with Lynch Syndrome (HNPCC)
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MMR
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What gene is associated with FAP (familial adenomatous polyposis)
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APC
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What gene is associated with MAP (MYH-associated polyposis)
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MYH
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What gene is associated with Peutz-Jeghers Syndrome
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STK11
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What genes are associated with JPS (juvenile polyposis syndrome
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SMAD4
BMPR1A |
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What gene is associated with Cowden syndrome?
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PTEN
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Which of the following cancer syndromes has
nearly 100% lifetime risk of colon cancer? -FAP -HNPCC (Lync) -PH -JP -CS |
-FAP
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Shat prophylactic surgery is recommended in Lynch?
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Remove uterus & ovaries after age 30 (when done with family) - do HRT
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What genes is lynch caused by?
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MMR - mismatch repair genes:
-MLH1 & MSH2 -MSH6 PMS2 |
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If you have at least 10 cumulative colonic adenomas what would you test for?
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APC & MYH
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If you have very early onset CRC with just a few adenomas what would you test for?
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Lynch (MSI/IHC)
If normal then -Li-Fraumeni -MAP -AFAP |