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14 Cards in this Set

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caffeine!

caffeine is responsible for the stimulant effect of coffee and tea. related compounds are theophylline (a more potent stimulant, small amount found in tea, given to asthmatics to dilate bronchila tubes) and theobromine (principal alkaloid of cacao beans, a mild stimulant)

structure of caffeine

caffeine is an alkaloid, which is [the general class of compound containing nitrogen, can be both hydrophobic and hydrophilic, so can dissolve in blood and cross the blood/brain barrier, (whihc is hydrophobic), so a lot of psychoactive drugs are alkaloids also morphine is too im p sure

caffeine looks like

a hexagon with Ns in it with a pentagon wih Ns in it on the right. There's things comin off of that.

caffeine content of drinks

1 cup coffee-100-175 mg


1 cup tea=30-60 mg


can of soda 40-50 mg


bar of chocolate 1-15 mg


decaf coffee 2-5mg

caffeine content of drugs

nodox 200 mg


excedrin 130mg


snapple 48 mg


mountain dew 55 mg


dr pepper 31 mg


dannon coffee yogurt 45 mg


starbucks coffee ice cream 60 mg

decaffeniating coffee way 1

1. extract with organic solvent-since coffee is water based, so only compounds that are soluable in both ater and hydrophobic solutions like alkaloids should be extracted.


a. methylene chloride used to be used but its carcinogenic so only used for REALLY FANCY coffee


b. ethyl acetate is advertised as natural

decaffinating coffee way 2

extract with water- soak gree beans in water, tho be careful not to extrant the whole flavors

way 3 super critcal decaffination

OH MAN this is so complicated and its not even on the study guide i cant even read the infographic

halflife of caffeine in the body

adult 3-5 hrs


baby less than 6 months 24 hrs


pregnant 7-8 hrs


smoker 3-4 hrs

effects of caffeine

central nervous system stimulant


diuretic


bronchial tubes dialation


gastric irritation


increase metabolic rate


mechanism of action of caffeine

blocks adenosine receptors, adenosine is a calming nuerotransmitter

normal action of adenosine

a nice diagram. lil adenosine recptor sitting on the cell membrane, outside of the cell it has a open traingle bit, inside theres a half circle bit, then the adenosine recptor binds to the recptor, making the circle bit turn to the left, step 3, a signal protein which is a circle goes in, postiive response and calming effect

action of caffeine

another lil pic. Competitive inhibioty, antagonist of adenosine. it goes under the andenosine and sits under one of the arms of the outside the cell bit, so that its too flat when the adenocine recptor comes along and it doesnt bind, so the lil red circle doesnt go in the bit. No calming effect results


(MAYBE SHOULD COME BACK TO THE STUFF NOT IN THE STUDY GUIDE WHEN I GET TO THIS CARD?)

(MAYBE AT LEAST BRIEFLY?)