Cns Tumors

Front 1

Cerebellum tumor.
Cell origin: undifferentiated embryonal cells. Homer Wright Rosettes, can spread through subarachnoid space/CSF, "frosting on brain," WHO grade IV, common in kids.

Back 1

Medulloblastoma

Front 2

WHO grade II, found in the walls around ventricles, most common spinal cord glioma, spreads through CSF, perivascular pseudorosettes and ependymal rosettes. Common in kids.

Back 2

Ependymoma

Front 3

Either primary or secondary (from astrocytoma). WHO grade IV. Most common primary tumor in adults.

Back 3

Glioblastoma

Front 4

Any tumor from oligodendrocytes or astrocytes

Back 4

Glioma

Front 5

Intermediate to high- grade non-Hodgkin's lymphomas, B cell type. Periventricular and often multiple. EBV associated with some. Found in elderly and immunocompromised.

Back 5

CNS lymphoma

Front 6

Vascular tumor seen with Van Hipple - Lindau disease, foamy stromal cells of unknown origin. Usually middle age patients.

Back 6

Hemangioblastoma

Front 7

Benign epithelial tumor from Rathke's pouch epithelium. Symptoms related to increased ICP: compression of pituitary gland, optic chiasm, 3rd ventricle. Bimodal age distribution: kids ages 5-14, Adults >50.

Back 7

Craniopharyngioma

Front 8

One type of glioma, preference for white matter, fried egg appearance, calcifications common, delicate capillary beds look like chicken wire, median survival 10 years.

Back 8

Oligodendroglioma

Front 9

Usually grade I or II, >60% of primary CNS tumors.

Back 9

Astrocytoma

Front 10

Extra axial, tumor of the schwann cells, usually sensory nerves, can dissect tumor off nerve.

Back 10

Schwannoma

Front 11

Extra axial, proliferation of schwann cells, fibrobladsts, and perineural cells, intrinsic to nerve.

Back 11

Neurofibroblastoma

Front 12

Grade I, circumscribed, mural nodule with a cyst, Rosenthal fibers, seen most in cerebellum (also optic nerve and hypothalamus). Common in kids.

Back 12

Pilocytic astrocytoma

Front 13

Most common CNS cancer in adults. Usually from lung, breast, and melanoma.

Back 13

Metastatic carcinoma

Front 14

Extra-axial, from arachnoid cap cells, tumor recapitulates normal features of these cells. Whorls, psammoma bodies, three grades (benign, atypical, malignant/anaplastic), usually a single tumor, higher grade increases recurrence rate. More common in females. 20% of primary brain tumors. Can cause seizures, can invade bone.

Back 14

Meningioma

Front 15

Three most common adult cancers

Back 15

Metastatic carcinoma
Glioma (astrocytoma, oligodendroglioma)
Meningioma

Front 16

Three most common kid cancers

Back 16

Pilocytic astrocytoma
Ependymoma
Medulloblastoma