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24 Cards in this Set

  • Front
  • Back

Receptors and agonists of ACh

Muscarinic (M1)( excitatory)- muscarine


Muscarinic (M2)( inhibitory)- muscarine and bethanechol


Nicotinic( excitatory)- nicotine

Receptor antagonist of Ach

M1- pirenzepine and atropine


M2- atropine and methoctramine


Nicotinic- Dihydro-Beta-erythroidine and alpha-bungarotoxin


Receptors and agonists of dopamine

D1(inhibitory)- dihydrexidine


D2( inhibitory)- bromocriptine


Receptors and agonists of GABA

GABA A receptors; inhibitory; muscimol


GABA B receptors; inhibitory; baclofen

Antagonists of GABA

GABA A- Bicuculline, picrotoxin


GABA B- 2-OH Saclofen

Glutamate receptors and agonists

NMDA ; excitatory; NMDA


AMPA; excitatory; AMPA


Kainate; excitatory; kainic acid, domoic acid


Metabotropic; inhibitory (presynaptic) ; ACPD, quisqualate

Glutamate antagonists

NMDA - 2-amino-5-phosphonovalerate and dizocilpine


AMPA - NBQX


kainate- ACET


Metabotropic- MPCG

Glycine receptors and agonists

inhibitory; beta-alanine and taurine

Glycine antagonists

Strychnine

Serotonin agonists and receptors

5-HT 1A ; inhibitory; eptapirone


5-HT 2A; excitatory; LSD


5-HT 3; excitatory; 2-methyl-5-HT


5-HT 4; excitatory; cisapride

Antagonists of serotonin

5-HT 1A ; metergoline and spiperone5-HT 2A; ketanserin5-HT 3; ondansteron5-HT 4; piboserod

Norepinephrine receptors and agonists

Alpha1; excitatory; phenylephrine


Alpha2; inhibitory(pre-synaptic); clonidine


Beta 1; excitatory; isoproterenol and dobutamine


Beta 2; inhibitory; albuterol

Norepinephrine antagonists

Alpha1; prazosinAlpha2; yohimbineBeta 1; atenolol and practololBeta 2; butoxamine

Histamine receptors and agonists

H1; excitatory; 2(m-fluorophenyl)-histamine


H2; excitatory; Dimaprit


H3; inhibitory; R-alpha-methyl-histamine

Histamine antagonists

H1- mepyramine


H2- ranitidine


H3- thioperamide


Orexins receptors and agonists

OX1; excitatory (glutamate co-release); orexins A


OX2; orexins A and B

Orexins antagonist

Suvorexant

Opioid receptors and agonists

Mu; inhibitory (pre-synaptic); bendorphin


Delta; inhibitory (post-synaptic); enkephalin


Kappa; inhibitory (pre-synaptic); dynorphin and salvinorin A

Antagonist of opioid

Naloxone

Agonists and receptors of tachykinins

NK-1; excitatory; Substance P, methylester NK-2: excitatory; neurokininA NK-3: excitatory; neurokinin B

Antagonists of tachykinins

NK-1; Aprepitant


NK-2; SaredutantNK-3; Osanetant

Agonists and receptors of endocannabinoid

CB1 ; inhibitory (pre-synaptic); anandamide and2-arachidonyglycerol

Antagonist of endocannabinoid

Rimonabant

Antagonists of dopamine

1) D1- phenothiazones


D2- Phenothiazones and butyrophenones