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39 Cards in this Set
- Front
- Back
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Methylphenidate is...
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a TCA
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3 possible treatments of choice for maintenance in bipolar-affective disorder
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1) lithium
2) atypical antipsychotic 3) lamotrigine |
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clomipramine is...
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TCA
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What do you you to treat OCD?
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1) SSRIs
2) clomipramine 3) exposure & response therapy |
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venlafaxine is...
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SNRI
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You can treat any of the anxiety disorders with...
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SSRIs
Other antidepressants vary across anxiety disorders. |
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Clonidine is...
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alpha2-adrenergic agonist
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Clonidine was initially developed for...
But is now used for... |
(Alpha-2 adrenergic agonist)
Essential hypertension Now: -opioid withdrawal -chronic pain -ADHD -hyperarousal/anxiety of PTSD and others... |
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What do you use for status epilepticus?
What do you need to be careful of / have on hand? |
Benzos, specifically
-Diazepam -Lorazepam -Midalozam (Uptodate says these are first-line; Ferrell disagrees) Decreasing respiration too much. - Keep flumazenil on hand |
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Zolpidem is AKA...
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Ambien
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Thiopental belongs to which class of drugs?
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Barbituates
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Sominex, Benadryl, Unisom all have what compound (and what class) in them?
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Diphenhydramine
H1 antagonist |
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Ramelteon is also known as...
And its mechanism of action is... |
Rozerem
melatonin receptor agonist (MT1, MT2) |
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What would be a reasonable first drug treatment for insomnia?
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Ramelteon: melatonin receptor agonist - little abuse/addiction potential
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Buspirone belongs to which class of drugs
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Sedative-hypnotics
Placebo? Partial agonist at a subset of 5-HT receptors |
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To treat ADHD you want to use a (psychodepressant/psychostimulant)
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Psychostimulant
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What types of psychostimulants can you use for ADHD?
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methylpheniate
d-amphetamine |
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H1 antagonists are associated with what side-effects?
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1) sedation
2) weight gain |
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muscarinic receptors are important in what system?
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parasympathetic
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Anticholinergic side effects include what?
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(opposite of DUMBELSS)
confusion blurry vision dry mouth tachycardia constipation urinary retention dry skin |
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Na-channel blockers lead to what side-effect?
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Arrythmias due to increased conduction times.
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What side-effects are associated with MAOI use?
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Serotonin syndrome
Hypertensive crisis |
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What is serotonin syndrome?
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Hunter Criteria (up to date):
Serotenergic agent + any of the following: 1) spontaneous clonus 2) inducible clonus & agitation or diaphoresis 3) ocular clonus and agitation or diaphoresis 4) tremor & hyperreflexia 5) hypertonia 6) temp above 38 and ocular clonus or inducible clonus Mental status changes include: anxiety agitated delirium restlessness disorientation Typical vital sign changes: tachycardia & hypertension hyperthermia possible |
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marinol is what type of drug?
Indications? |
Medical marijuana,
delta9-THC Antiemetic Glaucoma |
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Marijuana's mechanism of action?
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Agonist at anadamide/cannabinoid receptors
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What is anandamide?
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Natural cannabinoid, formed from arachidonic acid + amide
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Name this drug:
A mainstay in the treatment of bipolar disorder; also used in epilepsy; side effects include GI distress and rare, but potentially fatal, hepatotoxicity. |
Valproate
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What is Leu-enkephalin?
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It is an opioid peptide produced by the action of a peptidase on a larger peptide precursor.
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Loss of position on right body, pain on left body and right body weakness is BEST correlated anatomically with which of the following anatomic regions of the CNS?
A. Left spinal cord B. Left thalamus C. Multifocal cortex D. Right brainstem E. Right spinal cord |
E. right spinal cord
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Drugs for tonic-clonic & partial seizures?
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1) Carbamazepine
2) Phenytoin 3) Valproic acid 4) Lamotrigine |
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Drugs for absence seizures?
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1) Ethosuximide
2) Valproic acid 3) Clonazepam |
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Drugs for myoclonic seizures?
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1) Valproic acid
2) Clonazepam 3) Lamotrigine |
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Which of the following antifungal agents inhibits fungal beta-glucan synthesis?
A. 5-fluorocytosine B. amphotericin B C. caspofungin D. posaconazole |
C. caspofungin
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This drug decreases cerebral flow and is thus useful for patients with cerebral swelling.
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Thiopental
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This drug has a quick anesthesia onset and quick metabolic clearance (including extra hepatic clearance)
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Propofol
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What receptor is found mainly in the spinal cord interneurons and is inhibited by strychnine?
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Glycine receptors
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Best treatment choice for a reserpine-induced Parkinsonism
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Benztropine mesylate
(anti-cholinergic) Reserpine depletes monoamine stores |
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A parkinson's disease drug that is also an anti-viral agent
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Amantadine
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Has side effects that may include dry mouth and urinary retention
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Benztropine mesylate
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