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16 Cards in this Set
- Front
- Back
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MOA of benzos
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bind to GABA (BZ1 and BZ2) receptors to increase affinity and Cl- influx (leading to hyperpolarization)
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DOC for status
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diazepam or lorazepam
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antidote for benzos
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flumanezil
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MOA of buspirone
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partial agonist at 5HT1A receptor
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drug used for generalized anxiety in elderly
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buspirone
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MOS of barbs
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increase GABA induced Cl channel opening
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ultra-short barbs
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thipental
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long acting barbs
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phenobarb and mephenobarb
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ASEs of barbs
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increase porphyrin synthesis leading to AIP, increase hepatic enzyme activity
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barb used as anti-convulsant
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phenobarb
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MOA of conventional anti-psychotics
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antagonists at the post-junctional D2 receptors (increase andeylyl cyclase; inhibitd Gi)
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MOA of atypic anti-psychotics
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antagonize 5HT2, D2 and D4
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conventional antipsychotics with high potency
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haloperidol, fluphenazine
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conventional antipsychotics with low potency
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triflupromazine, chlorpromazine, thioridazine, mesoridazine
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atypical anti-psychotics
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risperidone, olanzipine, clozipine
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major ASEs of chlorpromazine
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cholestatic jaundice, photosensitivity
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